Intracavitary ECG for central venous access device tip location
“Utilizing IC-ECG instead of X-ray guidance (CXR or fluoroscopy) for medium and long term CVAD tip location (PICC and port) has resulted in significant cost reduction. This strategy should strongly be considered for improving the cost-effectiveness of CVADs implantation” Pinelli et al (2025).
Interprofessional CLABSI reduction
“Interprofessional CLABSI reduction efforts can be effective in a cardiac surgical intensive care unit and improve patient safety. Keys to success include teamwork, accountability, acceptance from intensive care unit staff, and support from hospital executive leaders” Mazzeffi et al (2025).
CLABSI prevention in ICU – Full Text
“This review highlights a persistent gap between knowledge and adherence to CLABSI prevention practices among ICU nurses. Strengthening education, institutional support, and diagnostic strategies is essential to reduce infection rates and improve patient safety” Alqaissi (2025).
Home care model for patients with PICC
“This study aimed to develop a mobile care application for peripherally inserted central catheter maintenance, which incorporated five functions: data recording, health education, image uploading, regular reminders, and online consultation” Zheng et al (2025).
Maintaining peripheral cannula patency
“Normal saline infusions have been proposed as an alternative for extending cannula lifespan. This study aims to address the clinical need for data on blood collection techniques in healthy participants” Lubila et al (2025).
Evaluation of NHS injectable medicines guide – Full Text
“To explore intravenous drug compatibility information needs of National Health Service (NHS) Injectable Medicines Guide (‘Medusa’) users. To develop consensus expert recommendations on the intravenous drug compatibility information that Medusa should include” Aguado Lorenzo and Jones (2025).
Managing CRBSI with antimicrobial lock therapy – Full Text
“Antimicrobial lock therapy can be considered a treatment option for managing CRBSIs, particularly in cases where removal of the implantable catheter is not feasible, allowing for salvage” Aksoy et al (2025).
Unplanned early implantable port removal – Full Text
“Implantable port catheters are vital for cancer treatment, but complications such as infections and mechanical failures pose challenges. Lymphoma and leukemia patients’ unique cellular abnormalities may influence these risks. This study aimed to determine whether the underlying disease or varying degrees of cytopenia increase the risk of unplanned early port removal” Lu et al (2025).
International OPAT survey – Full Text
“This study revealed significant variation in OPAT practice. Further study is needed to understand the reasons for these differences and whether better alignment of practice could improve patient outcomes, antimicrobial stewardship practice and resource utilization” Wolie et al (2025).
Needlestick injuries among Estonian nurses – Full Text
“This study aimed to assess the prevalence, contributing factors, and awareness of post-exposure prophylaxis (PEP) among Estonian nurses” Parm et al (2025)
Implantable port removal outcomes pilot study
“The primary end point of any future research on TIVAD maintenance should primarily be focused on the functionality of the TIVAD. The CINAS classification effectively standardizes reporting of TIVAD functionality” Douchy et al (2025).
Ultrasound-guided placement of central venous catheters in neonates
“We describe the insertion technique of an ultrasound-guided non-tunneled centrally inserted central catheter (CICC) placed in an extremely low-weight and extremely preterm neonate, adapting materials used for placing vascular access devices in the superficial veins of neonates” Rodriguez-Pere et al (2025).
Femoral venous access port case study – Full Text
“In an adolescent male with relapsed primary mediastinal lymphoma, complicated by complete SVC obstruction, we report the placement of a port into the right femoral vein by interventional radiology” Lian et al (2025).
AI-driven tool for CLABSI risk prediction
” The developed AI model shows strong potential for early CLABSI prediction using routine blood parameters. Future studies should focus on external validation and broader clinical application to enhance early infection prevention, particularly in resource-limited settings” Lahariya et al (2025).
Contrast injection via implantable port
“To compare the contrast enhancement (CE) value, injection rate and contrast material (CM) volume with and without the implanted port system during dynamic hepatic computed tomography (CT) scan” Moriwake et al (2025).
Patient satisfaction with implantable ports
“Patients expressed high satisfaction with low impact on comfort, psychological state and physical well-being. Maintenance experiences varied, highlighting the need for further investigation and a validated comprehensive questionnaire” Goossens et al (2025).
Repeat CLABSI in the same patient
“Repeat CLABSI in the same patient is not uncommon and can contribute significantly to overall inpatient CLABSI rates. Prior CLABSI should be considered a risk factor for future CLABSI” Sotak et al (2025).
OPAT drug stability data – Full Text
“The use of an elastomeric diffuser is favored to administer outpatient antibiotic therapy. A study published in 2022 highlighted the instability of several antibiotics in elastomeric devices at 37 °C. The objective was to evaluate the stability of nine time-dependent antibiotics that are unstable at 37 °C at lower concentrations and a reduced storage temperature of 32 °C” d’Huart et al (2025).
PICC insertion length prediction formula
“The PICC insertion length prediction formula could reduce excessive deep tip positioning, but further measures are required to enhance tip placement in the superior vena cava” Okuwaki et al (2025).
How to exchange a tunneled central venous catheter
“Patients with intestinal failure (IF) are dependent on tunneled central venous catheters (CVC) to provide parenteral nutrition. A method using a fibrous sheath (FS) was developed to preserve the central venous routes while exchanging CVC. We focused on the reduction of punctured catheter insertions for the FS method” Hashizume et al (2025).
Current landscape of OPAT practice across the United Kingdom – Full Text
“In this review, we examine the current landscape of OPAT practice across the United Kingdom (UK), assessing its clinical, economic, and operational impact” Durojaiye et al (2025).
CLABSI rates in patients with major burns – Full Text
“This study aimed to investigate the effects of catheter types used in patients with major burns on bloodstream infections and to predict sepsis status and manage its prognosis using a procalcitonin biomarker” Çinar et al (2025).
Vascular Access and IV Therapy Resource

Needle-free connector evaluation
“This study examined the performance of various NFC technologies with PICC and Midline. While no device eliminates BV, positive displacement NFCs showed lower flow reflux compared to the others when used with PICC. No difference between clamping sequences was observed for neutral and anti-reflux NFCs” Privitera et al (2025).
Peripheral intravenous cannula removal in children
“To determine the effects of using an alcohol-free, silicone-based adhesive remover spray and squeezing a stress ball on pain and fear of pain during the removal of peripheral intravenous cannulas and fixation materials (acrylate-based hypoallergenic adhesives) in children aged 6-9 years” Guzel Polat et al (2025).
Blood culture diagnostic stewardship model – Full Text
“The medical community recently experienced a severe shortage of blood culture media bottles. Rates of blood stream infection (BSI) among critically ill children are low. We sought to design a machine learning (ML) model able to identify children at low risk for BSI to improve blood culture diagnostic stewardship” Martin et al (2025).
Tunneling of centrally inserted central venous catheters
“The purpose of this article is to present a tunneling technique that allows the repositioning of the catheter exit site to the infraclavicular fossa using only the materials included in standard CICC kits” Benvenuti et al (2025).
Intravenous smart pump review
“The first programmable infusion pumps were invented over 50 years ago, but their adoption in hospitals was slow, and their initial functions were limited to basic programming in milliliters per hour” Blake et al (2025).
Safety-engineered port access needles – Full Text
“We have shown significant differences regarding product characteristics of safety mechanisms of port access needles. Our evaluation approach provides specific data for both, technical (e.g., single-handed activation) and personal device selection criteria (e.g., preference of the safety mechanism)” Gabler et al (2025).
Centrally inserted central catheter infection control practices – Full Text
“To enhance overall infection control performance among ICU nurses, it is crucial to raise the perception of the importance of patient safety management and implement systematic strategies targeting both the direct and indirect performance of CICC infection control” Park et al (2025).
Vascular access during out-of-hospital cardiac arrest – Full Text
“This study aimed to apply a Bayesian probabilistic framework to the Intravenous vs. Intraosseous Vascular Access for Out-of-Hospital Cardiac Arrest (IVIO) trial data to evaluate the likelihood of benefit for each vascular access method while incorporating various prior beliefs” Vallentin et al (2025).
Vascular access devices for patients with hematological cancer – Full Text
“Therefore, we aimed to compare the chemoport and Hickman central venous catheters (CVCs) as representative devices used in patients with hematological cancer” Han et al (2025).
Near-infrared guided vascular access in dogs – Full Text
“Use of NIR imaging for identification of superficial, peripheral veins is feasible in healthy beagles and hounds, regardless of shaving and administration of dexmedetomidine. This technology could be useful in other clinical scenarios” Bowden et al (2025).
Defining needle journey in ultrasound guided vascular access – Full Text
“This protocol offers a practical educational method for an ultrasound mastery learning program, enhancing needle identification, guidance, safety, and procedural success in venous and arterial cannulation” Ostroff and Moureau (2025).
Exit site definition for central venous access procedures – Full Text
“Despite widespread adoption of these innovations, current guidelines often confuse puncture and exit sites, leading to outdated recommendations. For example, guidelines labeling femoral or jugular access as high-risk often fail to differentiate between venipuncture and exit locations” Annetta et al (2025).
Impact of virtual visits for adult patients receiving home parenteral nutrition – Full Text
“Virtual visits demonstrate noninferiority to in-person visits based on the incidence of catheter complications and readmission rates. New evaluation techniques need to be developed for this high-risk populations in virtual visits to establish effective and safe patient management” Munroe et al (2025).
Anti-biofilm activity of central venous catheter lock solution – Full Text
“Genta-EDTA-Na2 used as intra-catheter locks may be a promising anti-biofilm candidate to be studied in a randomized controlled trial” Lebeaux et al (2025).
Tigecycline stability in elastomeric infusion devices – Full Text
“Tigecycline meets the UK YCD criteria of ≤5% degradation limit, indicating its suitability for both intermittent and continuous 24-h infusion in OPAT programs” Wolie et al (2025).
Self-administered outpatient parenteral antimicrobial treatment review – Full Text
“We conclude that S-OPAT is a viable model of care, demonstrating favourable clinical outcomes, although some safety concerns have been reported. The growing care demand now and in the future urges further development of S-OPAT care” Maaskant et al (2025).
Impact of noradrenaline administration on infusion phlebitis rates – Full Text
“We aimed to investigate the relationship between the total noradrenaline dose administered via PIVCs and the development of phlebitis by considering the influence of noradrenaline as a time-dependent covariate” Yasuda et al (2025).
Misplaced temporary dialysis catheter into the axillary vein – Full Text
“Post-procedure chest X-ray to confirm this access indicated that this central venous catheter (CVC) was misplaced, with its tip placed into the right axillary vein” Arif et al (2025).
Infective endocarditis treatment with OPAT – Full Text
“OPAT appears to be safe and effective for IE patients, with low mortality and relapse rates. However, increased readmission rates and IV-line complications warrant careful patient selection and monitoring. Further prospective trials are needed to refine OPAT protocols” Ashraf et al (2025).
How to locate femoral vein by anatomic landmarks – Full Text
“These datasets might be useful as additional support while performing femoral vein cannulation in complicated and challenging cases where the facility of radiological monitoring is not available” Ghosh et al (2025).
CLABSI reduction using tissue adhesive
“To investigate whether tissue adhesive (TA, 2-octyl blended with n-butyl cyanoacrylate) application to centrally/femorally inserted central catheters (CICCs/FICCs) exit sites could reduce the occurrence of central line-associated bloodstream infection (CLABSI)” Kwon et al (2025).
VIP score quality improvement project
“This QIP has successfully reduced early phlebitis rate in this patient population to 2.1%, which is now in-keeping with CDC guidance of <5%. In addition, there was a 65.5% improvement in documentation of VIP score demonstrating increased application of the tool in clinical practice” O’Donnell et al (2024).
AccuVein research protocol – Full Text
“To verify the effectiveness of AccuVeinAV300® in the success of peripheral intravenous catheterization in adults with difficult intravenous access, compared to the traditional clinical method” Bittencourt et al (2025).
Reducing peripheral intravenous catheter related blood stream infections
“A taskforce was convened to plan, develop and implement hospital-wide, evidence-based practice approaches, aligned with clinical care standards, to reduce the incidence of PIVC related infection” Sammut et al (2025).
Using a vein imaging device to assist peripheral intravenous catheterization in children
“This study was aimed at investigating the effect of the vein-imaging device used in peripheral intravenous catheterization on the success of the procedure in patients who presented to the children’s emergency department” Karaarslan et al (2025).
Ultrasound guided central venous catheter insertion
“oint-of-care ultrasonography bundle for CVC insertion is considered superior to, safer, and more cost-effective than the blind technique” Beniamen et al (2025).
Safe injection practices in healthcare
“This position paper provides healthcare professionals (HCP) updated guidance with corresponding evidence and rationale to support safe injection, infusion, medication vial, and point-of-care testing practices in healthcare settings” Ormsby et al (2025).
Accudrip gravity-based automatic infusion system – Full Text
“The gravity-based automatic infusion system showed high accuracy consistent with the theoretical rate of administration even under multiple infusion conditions of cancer patients with chemoport. This system (Accudrip) will greatly contribute to accurate drug administration and minimization of adverse events in real-world hospital settings” Park et al (2025).
3D virtual simulation game for teaching intravenous fluid therapy
“To describe the gamification process of peripheral intravenous catheterization (PIVC) and intravenous fluid therapy (IFT) in nursing education and conduct usability testing of the 3D virtual simulation game” Kuruca Ozdemir et al (2025).
Central venous catheter maintenance for cancer patients
“In the maintenance of central venous indwelling catheters for cancer patients, the implementation of a precise management model can significantly reduce the incidence of central venous indwelling catheter-associated complications, improve treatment compliance of patients, positively modulate patients’ psychological state, and harmonize the nurse-patient relationship” Xu et al (2025).