Study protocol for the evaluation of Malaysian OPAT services – Full Text
“This study aims to describe the safety, clinical indications and treatment outcomes of the OPAT service in Malaysia, assess patients’ satisfaction and experiences and determine the facilitators and barriers associated with the provision of the OPAT service in Malaysia” Lim et al (2025).
Plasma volume response to crystalloid fluid administration – Full Text
“Attenuation of the plasma volume response to bolus infusions of crystalloid fluid occurs. The second and third bolus might not increase cardiac preload enough to allow a correct diagnosis of fluid responsiveness. This problem is not shared by colloid fluid” Hahn and O’Brien (2025).
Epinephrine administration in pediatric out-of-hospital cardiac arrest – Full Text
“In this retrospective cohort study of pediatric patients with OHCA in the US and Canada, the route of epinephrine administration was not associated with survival to hospital discharge or prehospital ROSC. This may support the practice of administering epinephrine via IO or IV route” Okubo et al (2025).
Monoclonal antibody drug management – Full Text
“Monoclonal antibodies (mAbs) constitute a new form of immunotherapy that has shown great success in long-term tumour control. These injectable drugs are managed and compounded by the Pharmacy Intravenous Admixture Services (PIVAS) staff in a specified sterile environment” Cai et al (2025).
Village doctor availability to administer intravenous fluids for diarrheal illness – Full Text
“We found that village doctors located closer to main roads were more likely to be government trained but just as likely to administer intravenous fluids” Amin et al (2025).
Pathogenic bacteria features of central line-associated bloodstream infections – Full Text
“The early prediction of CLABSI in ICU patients by means of PCT, NLR, and PLR is of remarkable significance. It can provide a precious reference for clinical diagnostic and treatment strategies” Li et al (2025).
Impact of skilled nursing facilities on OPAT outcomes – Full Text
“In this study, 101 patients discharged to a SNF on OPAT required considerable post-hospital care coordination and experienced high readmission and mortality rates within 90 days, contributing to literature characterizing OPAT patients in other settings” Langenstroer et al (2025).
Organization of out-of-hospital emergency kits – Full Text
“While guidelines on contents and packing strategies of emergency kits for specific tasks and specialized situations exist, data for the design of out-of-hospital emergency kits in a general urban population is lacking. It may be possible to transfer the promising results of modern in-hospital packing strategies such as task-based package organization (TPO) to an Emergency Medical Service setting” Laxar et al (2025).
Student nurse support for infection-control practices – Full Text
“Pandemic incidences of hospital-acquired infections, central line-associated bloodstream infections (CLABSIs), and catheter-associated urinary tract infections (CAUTIs) increased, underscoring the importance of increasing workforce-ready nurses” Ashburn et al (2025).
Vascular access for puppies and kittens under 12 weeks – Full Text
“Catheters in the jugular vein may be preferred for puppies and kittens under 1.2 kg and 0.3 kg, respectively. Utilizing the cephalic vein for venous access may facilitate rapid and less technically challenging intravenous catheter placement in patients under 12 weeks old” Zilberfarb et al (2025).
Catheter dwell time and CLABSI risk – Full Text
“The aim of the study was to evaluate the relationship between catheter dwell time and the risk of CLABSIs caused by multidrug-resistant and common pathogens in patients with central venous catheters (CVCs) and peripherally inserted central catheters (PICCs)” Pitiriga et al (2025).
Hickman catheter associated infective endocarditis – Full Text
“We report a case of a 71-year-old female patient on a chronic hemodialysis (HD) program who had developed IE. Her first symptoms were fever and malaise. Transthoracic echocardiography (TTE) and transesophageal echocardiography (TEE) examinations were performed, revealing vegetations on the tip of HC and the anterior and posterior leaflets of the tricuspid valve (TV)” Šačić et al (2025).
Outcomes for patients receiving multi-chamber bags for the delivery of parenteral nutrition – Full Text
“This systematic review aimed to examine the evidence base for clinical outcomes and/or quality of life (QoL) in adults receiving PN as MCBs compared to COMs in hospital and community settings” Jones et al (2024).
Prevention of PICC associated UEDVT – Full Text
“Upper limb functional exercise combined with an intelligent grip ball can reduce the incidence of catheter-related thrombosis, improve coagulation function, increase compliance with functional exercise, and improve nursing satisfaction in patients with PICCs” Bu and Wu (2025).
Neonatal venipuncture analgesia – Full Text
“Neonatal exposure to pain can lead to altered pain perception in later years of life. Despite the availability of measures to alleviate pain, routine use is lacking. We decided to conduct a quality improvement (QI) study to increase the use of analgesia during venipuncture, a common procedure in neonatal intensive care units, from a baseline of 0% to 50% over 8 weeks” Shah et al (2025).
Taurolidine IV lock reduces recurrent CRBSI – Full Text
“This study demonstrates that the use of 1.35% taurolidine significantly reduces the rate of recurrent CRBSIs and CVC removals due to CRBSIs compared to 0.9% saline in adult patients with CIF reliant on HPS” Nerstrøm et al (2025).
Digitalised measures for CLABSI prevention compliance – Full Text
“Digitalised interventions for CLABSI prevention seem to be effective in reducing infection rates, likely because of increasing compliance to established guidelines for CLABSI prevention” Obama et al (2025).
Peripheral venous blood gas analysis Cochrane review – Full Text
“The primary objective of this review is to evaluate the performance of PVBGA by comparing it with the reference standard ABGA, which is assumed to be error-free for the diagnosis of (1) respiratory failure, (2) hypercarbia, and (3) metabolic disturbance (the three target conditions) in adults” Byrne et al (2025).
Blood culture contamination creep – Full Text
“In a low-COVID-19-burden secondary care teaching hospital setting, blood culture contamination rates have progressively increased over the past decade, irrespective of the pandemic. These findings underscore the importance of sustained vigilance in infection prevention and control practices, strict adherence to blood culture collection protocols, and the ongoing need for staff training” Jeverica et al (2025).
OPAT for patients with substance use disorder – Full Text
“Outpatient parenteral antimicrobial therapy (OPAT) is often withheld from individuals with substance use disorder (SUD), despite evidence suggesting similar outcomes. We investigated this using a large, nationwide claims database” Rogers et al (2025).
Prevention of central line infection among ICU nurses
“The educational intervention effectively improved ICU nurses’ knowledge regarding CLABSI prevention but did not significantly change their attitudes. Tailoring interventions to demographic characteristics may further enhance their effectiveness and contribute to better patient outcomes and healthcare quality” Alzoubi et al (2025).
Patient empowerment and CLABSI reduction
“To evaluate the impact of patient empowerment in reducing the incidence density (ID) of CLABSI” Reghini et al (2025).
Vascular Access and IV Therapy Resource
Study protocol for the evaluation of Malaysian OPAT services – Full Text
“This study aims to describe the safety, clinical indications and treatment outcomes of the OPAT service in Malaysia, assess patients’ satisfaction and experiences and determine the facilitators and barriers associated with the provision of the OPAT service in Malaysia” Lim et al (2025).
Plasma volume response to crystalloid fluid administration – Full Text
“Attenuation of the plasma volume response to bolus infusions of crystalloid fluid occurs. The second and third bolus might not increase cardiac preload enough to allow a correct diagnosis of fluid responsiveness. This problem is not shared by colloid fluid” Hahn and O’Brien (2025).
Epinephrine administration in pediatric out-of-hospital cardiac arrest – Full Text
“In this retrospective cohort study of pediatric patients with OHCA in the US and Canada, the route of epinephrine administration was not associated with survival to hospital discharge or prehospital ROSC. This may support the practice of administering epinephrine via IO or IV route” Okubo et al (2025).
Monoclonal antibody drug management – Full Text
“Monoclonal antibodies (mAbs) constitute a new form of immunotherapy that has shown great success in long-term tumour control. These injectable drugs are managed and compounded by the Pharmacy Intravenous Admixture Services (PIVAS) staff in a specified sterile environment” Cai et al (2025).
Village doctor availability to administer intravenous fluids for diarrheal illness – Full Text
“We found that village doctors located closer to main roads were more likely to be government trained but just as likely to administer intravenous fluids” Amin et al (2025).
Pathogenic bacteria features of central line-associated bloodstream infections – Full Text
“The early prediction of CLABSI in ICU patients by means of PCT, NLR, and PLR is of remarkable significance. It can provide a precious reference for clinical diagnostic and treatment strategies” Li et al (2025).
Impact of skilled nursing facilities on OPAT outcomes – Full Text
“In this study, 101 patients discharged to a SNF on OPAT required considerable post-hospital care coordination and experienced high readmission and mortality rates within 90 days, contributing to literature characterizing OPAT patients in other settings” Langenstroer et al (2025).
Organization of out-of-hospital emergency kits – Full Text
“While guidelines on contents and packing strategies of emergency kits for specific tasks and specialized situations exist, data for the design of out-of-hospital emergency kits in a general urban population is lacking. It may be possible to transfer the promising results of modern in-hospital packing strategies such as task-based package organization (TPO) to an Emergency Medical Service setting” Laxar et al (2025).
Student nurse support for infection-control practices – Full Text
“Pandemic incidences of hospital-acquired infections, central line-associated bloodstream infections (CLABSIs), and catheter-associated urinary tract infections (CAUTIs) increased, underscoring the importance of increasing workforce-ready nurses” Ashburn et al (2025).
Vascular access for puppies and kittens under 12 weeks – Full Text
“Catheters in the jugular vein may be preferred for puppies and kittens under 1.2 kg and 0.3 kg, respectively. Utilizing the cephalic vein for venous access may facilitate rapid and less technically challenging intravenous catheter placement in patients under 12 weeks old” Zilberfarb et al (2025).
Catheter dwell time and CLABSI risk – Full Text
“The aim of the study was to evaluate the relationship between catheter dwell time and the risk of CLABSIs caused by multidrug-resistant and common pathogens in patients with central venous catheters (CVCs) and peripherally inserted central catheters (PICCs)” Pitiriga et al (2025).
Hickman catheter associated infective endocarditis – Full Text
“We report a case of a 71-year-old female patient on a chronic hemodialysis (HD) program who had developed IE. Her first symptoms were fever and malaise. Transthoracic echocardiography (TTE) and transesophageal echocardiography (TEE) examinations were performed, revealing vegetations on the tip of HC and the anterior and posterior leaflets of the tricuspid valve (TV)” Šačić et al (2025).
Outcomes for patients receiving multi-chamber bags for the delivery of parenteral nutrition – Full Text
“This systematic review aimed to examine the evidence base for clinical outcomes and/or quality of life (QoL) in adults receiving PN as MCBs compared to COMs in hospital and community settings” Jones et al (2024).
Prevention of PICC associated UEDVT – Full Text
“Upper limb functional exercise combined with an intelligent grip ball can reduce the incidence of catheter-related thrombosis, improve coagulation function, increase compliance with functional exercise, and improve nursing satisfaction in patients with PICCs” Bu and Wu (2025).
Neonatal venipuncture analgesia – Full Text
“Neonatal exposure to pain can lead to altered pain perception in later years of life. Despite the availability of measures to alleviate pain, routine use is lacking. We decided to conduct a quality improvement (QI) study to increase the use of analgesia during venipuncture, a common procedure in neonatal intensive care units, from a baseline of 0% to 50% over 8 weeks” Shah et al (2025).
Taurolidine IV lock reduces recurrent CRBSI – Full Text
“This study demonstrates that the use of 1.35% taurolidine significantly reduces the rate of recurrent CRBSIs and CVC removals due to CRBSIs compared to 0.9% saline in adult patients with CIF reliant on HPS” Nerstrøm et al (2025).
Digitalised measures for CLABSI prevention compliance – Full Text
“Digitalised interventions for CLABSI prevention seem to be effective in reducing infection rates, likely because of increasing compliance to established guidelines for CLABSI prevention” Obama et al (2025).
Peripheral venous blood gas analysis Cochrane review – Full Text
“The primary objective of this review is to evaluate the performance of PVBGA by comparing it with the reference standard ABGA, which is assumed to be error-free for the diagnosis of (1) respiratory failure, (2) hypercarbia, and (3) metabolic disturbance (the three target conditions) in adults” Byrne et al (2025).
Blood culture contamination creep – Full Text
“In a low-COVID-19-burden secondary care teaching hospital setting, blood culture contamination rates have progressively increased over the past decade, irrespective of the pandemic. These findings underscore the importance of sustained vigilance in infection prevention and control practices, strict adherence to blood culture collection protocols, and the ongoing need for staff training” Jeverica et al (2025).
OPAT for patients with substance use disorder – Full Text
“Outpatient parenteral antimicrobial therapy (OPAT) is often withheld from individuals with substance use disorder (SUD), despite evidence suggesting similar outcomes. We investigated this using a large, nationwide claims database” Rogers et al (2025).
Prevention of central line infection among ICU nurses
“The educational intervention effectively improved ICU nurses’ knowledge regarding CLABSI prevention but did not significantly change their attitudes. Tailoring interventions to demographic characteristics may further enhance their effectiveness and contribute to better patient outcomes and healthcare quality” Alzoubi et al (2025).
Patient empowerment and CLABSI reduction
“To evaluate the impact of patient empowerment in reducing the incidence density (ID) of CLABSI” Reghini et al (2025).
Review of blood culture single-sampling strategy and initial specimen diversion – Full Text
“After combined implementation of SSS and initial specimen diversion (ISDT) in our region, we evaluated the proportion of sampling events with at least four bottles, with growth of relevant pathogens and with growth of coagulase-negative staphylococci (CoNS) before and after the intervention” Oldberg et al (2025).
Simulation for central venous catheterization training
“We hypothesized that resident physicians would prefer a simulation model with high functional task alignment over a model with higher superficial resemblance and lower functional task alignment in central venous catheter placement training” Gomaa et al (2025).
Management of a positive blood cultures
“There is considerable practice variation among ED physicians for the management of positive blood cultures in children across Canada. Incongruencies in the perceived impact of clinical factors on the likelihood of a true bacteremia, such as time-to-positivity, highlight the need for a standardized decision-making tool” Gouin et al (2025).
Technique for TIVAD implantation for chemotherapy
“This bicentric, retrospective study aims to compare the surgical vein cut-down approach with ultrasound-guided percutaneous vein puncture in terms of procedural success, complication rates, and operative efficiency” Fassari et al (2025).
The Irish national OPAT programme
“The study underscores the importance of national registries in monitoring and improving OPAT services and calls for integration of microbiological data to enhance stewardship” Reidy et al (2025).
Implantable port catheter detachment – Full Text
“The chest port was placed 10 months prior without complication. An initial fluoroscopic image of the chest revealed detachment and migration of the catheter towards the right atrium. The catheter was successfully retrieved with a gooseneck snare using an inferior approach through the femoral vein” Van Vorst et al (2025).
Central line placement in newborns
“Based on this initial experience, we conclude that ultrasound-guided innominate vein cannulation is feasible and safe for infants under 4.5 kg” D’ Alessandro et al (2025).
Venous blood collection guidelines
“The guideline includes practical tools, such as checklists and detailed information on sampling devices, to facilitate implementation. This initiative would help standardize blood collection practices, improve specimen quality, and enhance patient care by ensuring accurate laboratory results in clinical settings” Chang et al (2025).