IVUPDATE from IVTEAM
Adverse events frequency associated with daptomycin treatment during OPAT – Full Text
“The optimal laboratory monitoring frequency for outpatient parenteral antimicrobial therapy-related adverse events (OPAT-AEs) during daptomycin therapy is not well defined” Sunagawa et al (2026).
Hypodermoclysis utilization in long-term care
“Findings reveal heterogeneous use of hypodermoclysis in LTC, often at low volumes and over prolonged periods. Given the association between staffing levels and hypodermoclysis use, strengthened interprofessional engagement and collaboration may be needed to optimize hydration practices” Deniau et al (2026).
Bedside placement of tunneled dialysis catheters without fluoroscopy
“Ultrasound-guided, nonfluoroscopic bedside placement of right internal jugular vein tunneled catheters by nephrologists is feasible, safe, and cost-effective” Ganesh Srinivasa Prasad P et al (2026).
Paediatric drug product information review
“This study aims to improve the quality and completeness of the information provided by the SmPC for products with paediatric authorisation and to create greater awareness from both regulatory authority and market authorisation holders” Higi et al (2026).
Catheter-related bloodstream infections in hemodialysis – Full Text
“This study aims to identify and systematically assess the prevalence of Catheter-related bloodstream infections (CRBSI) and identify risk factors of CRBSI in hemodialysis (HD) patients” Aftab et al (2026).
Interventional radiology for human spaceflight
“These findings support the feasibility of image-guided drainage, decompression, and vascular access as candidate strategies for managing acute conditions encountered during exploration missions” Schutt et al (2026).
Impact of catheter design on hemodialysis catheter lock therapy
“This review argues that the biological effect ultimately achieved within the catheter may also be shaped by catheter architecture and lock-handling variables, including tip design, side-hole geometry, true luminal volume, fill ratio, lock density, interdialytic dwell, and aspiration practice” Corrêa et al (2026).
CLABSI prediction in children with acute leukemia
“These findings highlight the potential of machine learning models as effective decision-support tools for CLABSI risk stratification and underscore the need for further validation to facilitate broader clinical application” Zhang et al (2026).
Review of vasoactive agent infusion via peripheral routes – Full Text
“Implementing a standardized protocol to ensure the appropriate size and placement of PVC, optimizing the dosage and duration of vasopressors, and establishing vigilant nursing monitoring can facilitate the safe administration of vasopressors via PVC, with substantial implications for the early management of shock, particularly in resource-constrained settings” Singh et al (2026).
Impact of t-EDTA lock solution on central venous access device-associated complications
“Compared with control locking solution, use of 4% t-EDTA locking solution for CVADs reduced the incidence of a composite outcome of CVAD-associated bloodstream infection, catheter occlusion requiring alteplase use, and catheter removal due to occlusion among adult patients in the ICU” Ornowska et al (2026).
Reducing blood culture contamination in emergency departments
“Although national benchmarks recommend contamination rates of less than 3%, the Department of Veterans Affairs sets a more stringent goal of less than 1%. Many emergency departments face challenges in consistently meeting this standard. This project aimed to reduce blood culture contamination through a series of evidence-based interventions” Mikovich et al (2026).
Infections associated with peripheral venous catheters
“Although less frequent than central venous catheter infections, PVC-related bloodstream infections represent an important public health concern due to their widespread use. Incidence is likely underestimated because of limited reporting and variable diagnostic criteria” Piuco Preve et al (2026).
Decision-making during IV dressing application and removal – Full Text
“Our findings stress the need for targeted nursing education, structured support for reflective practice, and fostering a ward culture where nurses consistently apply evidence-based practices for PICC dressing and securement” Larsen et al (2026).
PICC placement in severely thrombocytopenic patients – Full Text
“PICCs represent a feasible and minimally invasive option for central venous access in patients with acute leukemia undergoing chemotherapy induction, with a favorable safety profile in terms of CR-bleeding, sDVT, and BSI in our real-world experience” Picardi et al (2026).
OPAT service gate keeping – Full Text
“These data highlight the central role of antimicrobial stewardship in OPAT gate keeping and the importance of measuring the unseen and wider healthcare service impact of OPAT” Rimbi et al (2026).
Taurolidine lock for recurrent catheter-related bloodstream infections – Full Text
“In patients with CIF and prior CRBSI, 1.35% taurolidine is a clinically superior and cost-saving secondary prevention strategy that reduces recurrent CRBSIs, CVC removals, and hospital resource use” Nerstrøm et al (2026).
Catheter-related superficial UEDVT – Full Text
“Catheter-related superficial venous thrombosis (SVT) of the upper extremity is a frequent complication of peripheral venous cannulation and longer peripheral devices such as midline catheters and peripherally inserted central catheters (PICCs)” Siniscalchi et al (2026).
Acute complications of nuclear medicine – Full Text
“Maladministration events occurred infrequently and were predominantly associated with diagnostic procedures, with minimal patient harm in most cases. In contrast, extravasation and toxicity related to therapeutic radiopharmaceuticals, particularly high-energy beta emitters, carried greater clinical significance” Sutaşır et al (2026).
Risk prediction models for CRBSI – Full Text
“Existing CRBSI prediction models demonstrate good discriminatory ability and clinical applicability. Identified risk factors can inform clinical early warning systems. However, methodological limitations and lack of external validation constrain current evidence” Liu et al (2026).
Epic OPAT order set review – Full Text
“We evaluated an Epic-based outpatient parenteral antimicrobial therapy (OPAT) order set to assess its impact on clinical workflows and analytics” Alsafadi et al (2026).
HAI prevention bundled management strategy – Full Text
“To systematically evaluate the application value and implementation effectiveness of a Failure Mode and Effects Analysis (FMEA)-based bundled management strategy in the precise prevention and control of hospital-acquired infections (HAIs) in the Intensive Care Unit (ICU) of a specialized oncology hospital” Zhang et al (2026).
Vancomycin dosing in CRBSI for hemodialysis patients
“The current vancomycin dosing protocol at HPSF does not consistently achieve therapeutic SVC in HD patients with CRBSI” Abd Majid et al (2026).