Targeted single-dose antibiotics to reduce CLABSI – Full Text
“Alteplase use has been associated with CLABSIs. Providing a single dose of post-alteplase antibiotics targeting the most likely site-specific pathogens may reduce the incidence of CLABSIs” Watchorn et al (2024).
The role of education to improve safer injection practices – Full Text
“Education is thought to be the most important factor in good injection practices that could reduce infections. Relevant knowledge through timely training is expected to have a positive impact on performance and compliance related to safe injections” Park et al (2024).
Drug delivery during syringe pump change over
“In a simulated environment with a cardiac output of 5 L/min, the CVP level and vertical position of the syringe pump generated bolus or backflow events during the syringe pump changeover” Lucchini et al (2024).
Intravenous line labels for high-alert drugs
“The label can be used as a technology to prevent misidentification of high-alert medications administered to critically ill patients through intravenous lines, thereby enhancing medication safety in healthcare institutions” de Kassio Nunes et al (2024).
Vein visualisation technology for peripheral IV access in paediatric patients – Full text
“Vein visualisation technology allows for a rapid, thorough assessment of patients’ vasculature to determine an optimal site for PIVC placement beyond what is visible to the naked eye or achievable using traditional methods” Weathers et al (2024).
CLABSI reduction in preterm neonates
“To compare the incidence of central line associated blood stream infections (CLABSI) with the use of umbilical venous catheters (UVC) as primary vascular access in preterm neonates with peripherally inserted central catheters (PICC)” Arun et al (2024).
Safety of peripherally infused vasopressors
“Peripherally infused sympathomimetic vasopressors are safe to administer up to 24 hours with a low incidence of extravasation events while avoiding CVC placement in the majority of patients” Zichichi et al (2024).
Ultrasound-guided CVC placement-related complications in neonates
“No significant difference was detected in the incidence of hematoma or venous thrombosis between the control and ultrasound groups. Other complications, such as pneumothorax, hemothorax, phlebitis, and cardiac tamponade, rarely occurred” Cui et al (2024).
IV and subcutaneous modes of administration in oncology patients
“Compared with IV administration, SC oncology treatment is a preferred option by patients and HCPs, increasing optionality and reducing treatment time while simultaneously increasing capacity and reducing the financial burden on healthcare systems” Aguiar-Ibáñez et al (2024).
OPAT continuous infusions – Norwegian experience – Full Text
“While OPAT in Norwegian healthcare has been rare, a new continuous ambulatory delivery device (CADD) allowing multiple daily dosing treatments has been innovated making OPAT more accessible” Skogen et al (2024).
Detection of infusion-related microplastics
“This work examined the content, type, shape, and size of M/NPs released directly into the bloodstream from medical devices via saline solution during intravenous (IV) injection” Mou et al (2024).
Ultrasound-guided cannulation training in therapeutic apheresis units
“USGC is a useful tool to reduce the need for CVAD. Training across multiple apheresis units is a lengthy procedure, but it can be successfully implemented” Putensen et al (2024).
Blood collection from central venous access devices
“To explore the facilitators of and barriers factors of evidence-based decision-making in CVAD blood collection in clinical practice” Qian et al (2024).
Pediatric emergency department based OPAT
“Our results affirm that pediatric emergency-based OPAT is a safe yet effective practice in children with good clinical outcome. We believe that a reduction in admissions translates to better hospital resource utilization” Bin Salleeh et al (2024).
Comparing midline catheter and PICC in cancer patients – Full Text
“This study aims to investigate the outcomes of PICC, and MC devices in patients undergoing chemotherapy” Beatrice et al (2024).
Central catheter-associated bloodstream infection surveillance
“Prospective CLABSI surveillance indicated stable incidence densities per 1000 catheter-days, but there were significant shifts of causative microorganisms over time” Obenhuber et al (2024).
Factors associated with failure of intraosseous access in prehospital trauma
“These findings suggest that intraosseous devices are a viable alternative for establishing vascular access in prehospital military settings. However, success rates were slightly lower than previous reports, potentially due to the severity of injuries in the study cohort” Rittblat et al (2024).
Intracavitary ECG-guided PICC in pediatric patients systematic review – Full Text
“IC-ECG-guided PICC placement is a highly effective and safe method for pediatric patients, including neonates, offering significant advantages over traditional techniques” Zhang et al (2024).
Risk factors for CLABSI in pediatric intensive care – Full Text
“Pediatric intensive care patients with chronic CVCs receiving parenteral nutrition, those on non-opioid sedative infusions, and those with more central line days are at increased risk for CLABSI despite current prevention measures” Marks et al (2024).
CLABSI outbreak following contaminated saline incident – Full Text
“The characteristics of R. pickettii-related central line-associated bloodstream infection (CLABSI) outbreak in pediatric hematopoietic stem cell transplant (HSCT) recipients are presented in this study” Çelen et al (2024).
CLABSI rates in Colombia 2015-2018 – Full Text
“Central line-associated bloodstream infections (CLABSIs) are a significant healthcare challenge globally, increasing mortality risk and complicating central vascular catheter use. In Colombia, few studies have assessed the impact of CLABSIs on hospital stay and mortality” Mosquera et al (2024).
Daptomycin use in pediatric patients – Full Text
“Despite substantial reports evaluating the clinical outcomes of DAP within the adult population, real-world data are lacking in children. The primary goal of this evaluation was to describe the clinical characteristics and outcomes of DAP use in pediatric patients across a wide range of infections” Persha et al (2024).
Tunnelled cuffed centrally inserted central catheter removal – Full Text
“There is little information available to guide best practice when removing this type of CVAD. At our institution, TC-CICCs are removed by using either the traction or dissection methods. This study will describe the outcomes associated with each technique” Borello et al (2024).
Novel implantable port insertion technique – Full Text
“The implantation of this CV-port device demonstrated comparable success and complication rates to conventional devices, with the added potential benefit of eliminating complications associated with the use of a peel-away sheath” Iguchi et al (2024).
Effectiveness of taurolidine antimicrobial catheter locks – Full Text
“Taurolidine lock treatment for children with central-line PN resulted in a substantial decrease in CRBSI episodes and related hospitalizations” Ling et al (2024).
Successful peripheral intravenous catheter placement – Full Text
“The primary objective of the present study was to examine the effect on venous dilation, procedure duration and pain severity of local heat, cold and vibration applications performed on the intervention area before peripheral intravenous catheterization in adults” Yılmaz and Yılmaz (2024).
Impact of sterile gloving during central line hub manipulation – Full Text
“To our knowledge, no study has reported compliance with wearing sterile gloves during these manipulations, nor the impact of not wearing sterile gloves on the cleanliness of the fingers of healthcare workers (HCWs) just before manipulating the connectors” Dos Santos et al (2024).
Vessel misidentification during CVC placement – Full Text
“Anesthesiologists should be aware of anatomical variations during IJV catheterization. Ultrasound with Doppler is crucial for accurate artery identification” Choi and Oh (2024).
Central line-associated bloodstream infection rates in children – Full Text
“Failure to adjust for patient factors, particularly acuity and complexity of disease, may miss clinically significant differences in CLABSI rates, and may lead to inaccurate interpretation of the impact of quality improvement efforts” Srinivasan et al (2024).
Review of OPAT with carbapenems – Full Text
“Parenteral carbapenems are effective, and well-tolerated OPAT treatment options; nonetheless, further studies are warranted to optimize the stability and/or dosing regimens of meropenem and enable its wider use” Wolie et al (2024).
CRBSI in hemodialysis patients – Full Text
“The incidence of CRBSI was found to be 0.78 episodes per 1,000 catheter-days. Acute hemodialysis catheter type and anemia were associated with increased risk for CRBSI, with a P-value less than 0.05” Bitunguramye et al (2024).
Manual administration of subcutaneous immunoglobulin – Full Text
“For infusion of Ig20Gly by manual administration, a syringe and butterfly needle are used; patients are advised to start infusion at 1-2 mL/min to prevent discomfort. Overall, manual administration of Ig20Gly offers an effective and well-tolerated alternative to administration by infusion pump” Grosse-Kreul et al (2024).
Use of tissue adhesive for neonatal intravenous access devices – Full Text
“There is a gap in the literature on the use of TA for securing vascular access devices in neonates, particularly regarding its safety and effectiveness in preventing failures and complications” Souza et al (2024).
Reducing PICC-related complications – Full Text
“Daily PICC assessment, particularly in patients with prolonged catheter use, PICC insertion into the brachial vein, or in postoperative care after cardiac surgery may significantly reduce CLABSI and CRT cases” Oviedo-Torres et al (2024).
Laboratory abnormalities found during OPAT – Full Text
“While laboratory abnormalities are frequently observed during OPAT, they rarely lead to discontinuation of OPAT. Specific patient, treatment and laboratory characteristics were associated with the occurrence of laboratory abnormalities” Stoorvogel et al (2024).
Reducing CVC duration in very low-birth-weight infants – Full Text
“The change from slow to fast enteral feeding progression for very low-birth-weight infants significantly decreased the central venous catheter duration with no adverse outcomes” Benguigui et al (2024).
Identifying work-related injuries among healthcare workers – Full Text
“HCWs face numerous daily hazards including needlestick injuries, chemical exposures, ergonomic strains, and psychological stressors crucial for their health and healthcare system functionality” Alqithami et al (2024).
Epinephrine route of administration in out-of-hospital cardiac arrest
“This retrospective analysis of a national EMS database revealed that IO epinephrine was negatively associated with ROSC. Additionally, there appears to be a finite time window during which intravenous epinephrine remains superior to the intraosseous route even if there are brief initial delays in IV drug delivery” Hubble et al (2024).
Neonatal vascular access complications
“In this study, the prolonged dwell time and smaller sized catheter was found to be independent predictors of total complications and CLABSI, respectively. The independent predictive effects of postconceptional age and body weight should be addressed in larger studies as potential risk factors” Simsek et al (2024).
Central line bundle implementation study – Full Text
“The study emphasized the significance of training in enhancing understanding and adherence to central line bundling protocols in ICUs. Participants exhibited a high level of knowledge and commitment to recommended practices, indicating that this training can have a favorable effect on CLABSI rates” Singh et al (2024).
Technique for tunneled hemodialysis catheter exchange
“The halfway technique may be recommended over the standard technique of tunneled catheter insertion due to shorter operative time, lower rate of hematoma formation, with non-inferior 1-year patency rates and comparable technical success and infection rates” Kamhawy et al (2024).
Association between necrotizing enterocolitis and CVC type
“Umbilical venous catheters (UVC) have been associated with an increased risk of necrotizing enterocolitis (NEC). We aimed to assess the relationship between the type of initial central venous access in preterm infants and NEC” Abda et al (2024).
OPAT adverse event prediction
“This study aimed to conduct a scoping review of machine learning (ML) techniques in outpatient parenteral antimicrobial therapy (OPAT) for predicting adverse outcomes and to evaluate their validation, implementation and potential barriers to adoption” Challener et al (2024).
Catheter-related thrombosis in neonates
“he incidence of central venous catheter-related thrombosis and the long-term effects of thrombosis on catheterized veins in neonates is unknown. We therefore determined the incidence of central venous thrombosis, identified associated risk factors, and evaluated outcomes at 6 months” Xiong et al (2024).
Vascular access training in the emergency department – Full Text
“Education and training in vascular access is a critical component to delivering quality vascular access care. Given that organizations must invest resources to implement and sustain high-quality vascular access programming, we aimed to demonstrate the cost effectiveness of a program (Operation STICK (OSTICK)) in the emergency department (ED)” Bahl et al (2024).
BSI in children and role of repeat blood cultures
“Repeat blood cultures are common in children after an initial positive culture. However, in contrast to adults, there are little data to help guide clinicians when a repeat culture is necessary to assess for persistent bacteremia. This study identifies factors associated with persistent bloodstream infections (BSI) in children to inform diagnostic stewardship” Puthawala et al (2024).
Predicting catheter-related thrombosis risk associated with central venous access devices
“Our study aims to construct and validate a predictive model for CRT risk in patients with cancer. It offers the possibility to identify independent risk factors for CRT and prevent CRT in patients with cancer” Ma et al (2024).
CRBSI reduction following use of taurolidine-citrate-heparin IV locking solution
“The aim of this study was to analyze the effect of systematic sealing of hemodialysis catheters in the ICUs of the Hospital Clínic de Barcelona on the incidence of hemodialysis catheter-related blood stream infections (CRBSI)” Del Risco Zevallos et al (2024).
Review of topical skin antisepsis in neonates
“Our findings indicate that both extremely preterm and very low birth weight infants are particularly susceptible to skin toxicities from pre-procedural antiseptic preparations” Mulinda et al (2024).
CLABSI differences according to catheter type – Full Text
“CABSI in catheters other than short-term non-tunnelled CVC are more commonly caused by virulent organisms including S. aureus and Gram-negative bacteria. Catheter type should be considered when selecting empirical antimicrobial therapies” MacPhail et al (2024).
Medication errors in obstetric anesthesia
“Implementation of various types of best practice cost effective mitigation strategies include recommendations to improve drug labeling, optimize storage, determine correct medication prior to administration, use non-Luer epidural and intravenous connection ports, follow patient monitoring guidelines, use smart pumps and protocols for all infusions, disseminate medication safety educational material, and optimize staffing models” Sharpe et al (2024).
How to design a cancer infusion center
“The current study performed a post-occupancy evaluation on a new cancer infusion center with pod-like layout and compared results to a pre-occupancy evaluation to investigate the impact of different cancer infusion center designs on staff efficiency and patient and staff satisfaction” Jalalianhosseini et al (2024).