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OPAT antimicrobial stability testing guidance – Full Text

“In conclusion, harmonization of antimicrobial stability testing to form a global OPAT-specific regulatory framework, particularly considering ‘areas of variation’ amongst current guidance, is required. We call for the development of a global OPAT antimicrobial stability testing framework with consensus from accepted antimicrobial stability criteria, expert opinion and pharmacopoeial best practice” Naicker et al (2024).

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Contaminated blood culture case study – Full Text

“This case highlights the risks associated with empiric antibiotic treatment of patients with suspected bacteremia, the implications associated with improper blood culture collection technique leading to false positive results, and the importance of interpreting a laboratory result within the context of the patient’s clinical status rather than relying solely on Systemic Inflammatory Response Syndrome (SIRS) criteria” Ordookhanian et al (2024).

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Occupational exposure to blood and body fluids – Full Text

“Primary care workplaces where occupational exposure to blood and body fluids may occur should have policies and procedures in place to manage such incidents. All healthcare workers should be immunised against hepatitis B and ideally should have documentation of their antibody response to vaccination” Pierce (2024).

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ChatGPT role in understanding radiopharmaceutical extravasation – Full Text

“Based on these results we concluded that ChatGPT may be a reliable resource for patients interested in radiopharmaceutical extravasations. However, these validated and verified ChatGPT responses differed significantly from official positions and public comments regarding radiopharmaceutical extravasations made by the SNMMI and nuclear medicine staff” Alvarez et al (2024).

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Value of time to positivity in blood cultures – Full Text

“Time to positivity (TTP) refers to the duration required for a microbiological culture test to indicate a positive result, marking the onset of detectable bacterial or fungal growth in the sample. Numerous variables, including patient characteristics, infection source, former antimicrobial therapy, blood sample volume, and sample transportation time can influence the value of TTP” Maffezzoli et al (2024).

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Management of residual volumes in intermittent medication infusions

“This review will improve understanding of current practices by examining flushing procedures used in the management of residual volume, identifying instances when residual volume is discarded, documenting effects on dosing, examining the impact on patient outcomes, and examining possible environmental harm from waste disposal of undelivered medication” Rout et al (2024).

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Peripheral intravenous catheter standard of care

“Our aim is to provide concise guidance that will enhance and standardize practices related to PIVC. By consolidating current standards of practice into a comprehensive document, our framework seeks to advance the quality of care and improve patient safety” Thompson et al (2024).

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Reducing blood culture contamination – Full Text

“The study demonstrated a substantial reduction in blood culture contamination rates through targeted interventions, highlighting the efficacy of combining evidence-based strategies with interdisciplinary teamwork to improve patient care outcomes” Eisenberg et al (2024).

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Occupational exposure to blood and body fluids – Full Text

“Primary care workplaces where occupational exposure to blood and body fluids may occur should have policies and procedures in place to manage such incidents. All healthcare workers should be immunised against hepatitis B and ideally should have documentation of their antibody response to vaccination” Pierce (2024).

Read More »

ChatGPT role in understanding radiopharmaceutical extravasation – Full Text

“Based on these results we concluded that ChatGPT may be a reliable resource for patients interested in radiopharmaceutical extravasations. However, these validated and verified ChatGPT responses differed significantly from official positions and public comments regarding radiopharmaceutical extravasations made by the SNMMI and nuclear medicine staff” Alvarez et al (2024).

Read More »

Value of time to positivity in blood cultures – Full Text

“Time to positivity (TTP) refers to the duration required for a microbiological culture test to indicate a positive result, marking the onset of detectable bacterial or fungal growth in the sample. Numerous variables, including patient characteristics, infection source, former antimicrobial therapy, blood sample volume, and sample transportation time can influence the value of TTP” Maffezzoli et al (2024).

Read More »

Management of residual volumes in intermittent medication infusions

“This review will improve understanding of current practices by examining flushing procedures used in the management of residual volume, identifying instances when residual volume is discarded, documenting effects on dosing, examining the impact on patient outcomes, and examining possible environmental harm from waste disposal of undelivered medication” Rout et al (2024).

Read More »

Peripheral intravenous catheter standard of care

“Our aim is to provide concise guidance that will enhance and standardize practices related to PIVC. By consolidating current standards of practice into a comprehensive document, our framework seeks to advance the quality of care and improve patient safety” Thompson et al (2024).

Read More »

Reducing blood culture contamination – Full Text

“The study demonstrated a substantial reduction in blood culture contamination rates through targeted interventions, highlighting the efficacy of combining evidence-based strategies with interdisciplinary teamwork to improve patient care outcomes” Eisenberg et al (2024).

Read More »

Review of antiseptics for neonatal skin disinfection

“All three antiseptics [2% chlorhexidine gluconate in 70% isopropyl alcohol(CHG + IPA), 10% Povidone Iodine(PI), and 70% isopropyl alcohol(AL)] cause significant reduction in bacterial colony counts. CHG + IPA has the maximum efficacy as assessed by log reduction of bacterial colony counts with optimal residual effect favouring its usage in term neonates” Jagalasar et al (2024).

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