CLABSI criteria in pediatric oncology patients – Full Text
“The aim of this study was to investigate the applicability of the central line-associated bloodstream infection (CLABSI) criteria of the Centers for Disease Control and Prevention in pediatric oncology patients” van den Bosch et al (2024).
ClearGuard HD caps in pediatric hemodialysis patients
“Routine use of ClearGuard caps in pediatric dialysis centers was associated with a reduction of HD CA-BSI rates in pediatric HD patients” Nau et al (2024).
Post CVC removal blood stream infection in neonates – Full Text
“Antibiotic administration upon CVCs removal does not significantly reduce the incidence of PCRS but offers less post-catheter removal blood stream infection” Ji et al (2024).
CLABSI bundle efficiency in ICU – Full Text
“Standardized ratios proved helpful in identify increasing trends of CLABSI in the ICU and monitoring the impact of a simple effective tool, i.e., training on and implementation of a bundle for CVC management” Boni et al (2024).
CLABSI rates associated with private equity hospital acquisition
“This increase in hospital-acquired conditions was driven by a 27.3% increase in falls (P = .02) and a 37.7% increase in central line-associated bloodstream infections (P = .04) at private equity hospitals, despite placing 16.2% fewer central lines” Kannan et al (2023).
Extent of device-associated healthcare infections in ICU – Full Text
“The study sheds light on the proportion, types of device-associated healthcare infections, and underlying etiological agents associated with these infections in our institute’s ICUs, thereby facilitating a better understanding of the healthcare-associated infection landscape within our facility” Gade et al (2023).
Suggested CLABSI benchmark rate in Saudi Arabia – Full Text
“An overall CLABSI rate of 4.29 per 1000 central line days was reported during the study period” AlSaleh et al (2023).
CLABSI misclassification outcomes
“We present examples of misclassification of bloodstream infections into CLABSI by the CDC’s definition and present the financial implications of such misclassification and potential long-term implications” Sopirala et al (2024).
Blood stream Infections in chronic hemodialysis patients – Full Text
“We noted an increased prevalence of gram-negative pathogens in the etiology of BSI in HD patients. Based on our findings, additional empirical antibiotics addressing gram negative bacteria have been added to our empirical treatment protocol” Schamroth Pravda et al (2024).
Antimicrobial potential of haemostatic disc – Full Text
“To evaluate the antimicrobial potential of the potassium ferrate haemostatic disc on Gram-positive (Staphylococcus aureus) and Gram-negative (Klebsiella pneumoniae, Pseudomonas aeruginosa) bacteria and on Candida albicans” Gough et al (2023).
INICC report of healthcare associated infections
“Reporting on the INICC study results from 2015 to 2020, conducted in 630 ICUs across 123 cities in 45 countries spanning Africa, Asia, Eastern Europe, Latin America, and the Middle East” Rosenthal et al (2024).
CLABSI prevention care bundle implementation
“Thanks to the implementation of the care bundle, the rate of infections and the number of accesses to the central line decreased, while the critical care nurses’ knowledge of evidence-based guidelines, compliance with the guideline recommendations in central line-related nursing interventions, and attitudes towards evidence-based nursing improved” Şanlı et al (2023).
CLABSI rates in low-middle income countries
“We implemented a multidimensional approach, incorporating an 11-element bundle, education, surveillance of CLABSI rates and clinical outcomes, monitoring compliance with bundle components, feedback of CLABSI rates and clinical outcomes, and performance feedback in 316 ICUs across 30 low- and middle-income countries (LMICs)” Rosenthal et al (2023).
Ethanol lock for CLABSI prevention in pediatric patients – Full Text
“Ethanol lock therapy is effective in preventing infection related to central venous catheter use in pediatric patients. Further study is warranted to determine the optimal protocol for, and incidence of, adverse events related to use of ELT” Sierra et al (2023).
PICC associated infection treatment case study – Full Text
“We report a novel case of T. bernardiae bacteremia in a paraplegic patient due to a peripherally inserted central catheter- (PICC-) associated infection that was treated successfully with piperacillin/tazobactam” Chapman and Nichols (2023).
CLABSI biofilm growth dynamics – Full Text
“Our findings could explain why early dissemination of cells in C. albicans and S. aureus prevents us from confirming or ruling out the catheter as the source of the bloodstream infection using the cut-off of 120 minutes in the DTTP technique” Díaz-Navarro et al (2023).
CLABSI rates in Dutch neonatal intensive care units – Full Text
“Being the largest collection of data on the burden of neonatal CLABSI in The Netherlands, this epidemiological overview provides a solid foundation for the development of a collaborative platform for continuous surveillance, ideally leading to refinement of national evidence-based guidelines” Jansen et al (2023).
CLABSI surveillance data validation – Full Text
“The CLABSI data reported to the THAS system are generally reliable. This study showed the need for ongoing validation processes and quality improvement to maintain the accuracy and validity of the surveillance data” Wu et al (2023).
Central catheter CLABSI salvage
“The incidence rate of CLABSIs in an expert HPN centre remains low. In case of CLABSIs, according to specific protocol, approximately 50% of CVC were removed immediately (essentially due to bacteriological characteristics). In case of CLABSIs and without initial complication, 80% of CVCs can be maintained at 3 months. These results justify a conservative attitude according to standardized protocol” Cohen et al (2023).
CVC replacement after candidemia – Full Text
“Deferred central venous catheter (CVC) replacement places children with intestinal failure (IF) at risk of complications. We hypothesized that early CVC replacement after uncomplicated candidemia is safe and beneficial” Katz et al (2023).
CLABSI most commonly reported type of nosocomial infection in PICU – Full Text
“A total of 51 patients developed 145 nosocomial infections. Central line-associated bloodstream infections (CLABSIs) were the most commonly reported type of nosocomial infections (28.3%). The majority of the isolated organisms (58.7%) were gram-negative, followed by fungal infections (35.1%) and gram-positive organisms (6.2%)” Almazeedi et al (2023).
CLABSI surveillance criteria – Full Text
“Modified criteria were not superior to CDC/NHSN criteria for surveillance. Thus, there is a scope of improving the modified criteria for the purpose of surveillance. CLBSI load was higher; CLABSI bundle for prevention is thus highly recommended” Rai et al (2023).
CLABSI education linked to total parenteral nutrition administration
“There is a major need to improve the knowledge and practice of critical care nurses in India regarding central line-associated bloodstream infection (CLABSI), which is a serious potential complication of total parenteral nutrition (TPN)” Gaur and Natha (2023).
Organizational factors and CLABSI prevention
“Organizational culture is the most significant factor affecting nurses’ practice of CLABSI prevention” Kim and Choi (2023).
Did COVID-19 increase CLABSI rates – Full Text
Did COVID-19 increase CLABSI rates Abstract: This study investigated how the Coronavirus Disease 2019 (COVID-19) pandemic has affected the rate of healthcare-associated infections (HAIs). PubMed, Scopus and Google Scholar were searched to identify potentially eligible studies published from December 2019 to September 2022. A random effect model was used to determine the changes in the […]
IV lock salvage strategy for implantable port infections
“Little is known about efficacy and safety of ethanol lock therapy (ELT) to treat totally implantable venous access device (TIVAD) infections. The objective of this trial was to evaluate the effectiveness and safety profile of a local treatment with ELT without removal for TIVAD infection due to coagulase-negative staphylococci” Lesens et al (2023).
CLABSI diagnosis – CVC salvage or removal – Full Text
“The aim was to determine whether salvage treatment with systemic antibiotics is a safe and effective strategy for Enterobacterales bloodstream infections (BSI) in pediatric oncology patients with a central venous catheter (CVC)” van den Bosch et al (2023).
CLABSI mortality risk factors – Full Text
“The microbiological trends of the study population demonstrated a steady increase of CLABSI caused by Candida spp. with a predominance of Gram-negative pathogens” Alwazzeh et al (2023).
Correlation between biochemistry results and CLABSI
“Clinical studies have not fully assessed the potential impact of patients’ biochemical indicators on the rate of positive for central venous catheter tip microorganism culture (PCMC)” Zhan et al (2023).
Ultrasonographic findings of CRBSI
“Ultrasound findings are useful for diagnosing CRBSI. However, the sensitivity of sonographic findings is low and abnormal sonographic findings are sometimes absent in children with CRBSI; therefore, physicians should not rule out CRBSI based on normal sonographic findings, especially in patients a CVC and a positive blood culture” Hosokawa et al (2023).