Complication rates in patients receiving continuous renal replacement therapy
To analyze the practice pattern of vascular access use and complication rates in patients receiving continuous renal replacement therapy from a large Chinese urban medical center” Ten et al (2019). Abstract: OBJECTIVE: To analyze the practice pattern of vascular access use and complication rates in patients receiving continuous renal replacement therapy from a large Chinese […]
Pharmacokinetics of continuous-infusion ceftazidime in febrile neutropenic children
To conduct a population pharmacokinetic analysis of continuous-infusion ceftazidime in a retrospective cohort of paediatric HSCT patients” Cojutti et al (2019). Abstract: OBJECTIVES: To conduct a population pharmacokinetic analysis of continuous-infusion ceftazidime in a retrospective cohort of paediatric HSCT patients who were empirically treated for febrile neutropenia (FN) and who underwent therapeutic drug monitoring of […]
Complications of totally implantable central venous port system insertion
The aim of the present study was to describe the procedure of totally implantable central venous port system (TICVPS) insertion performed at our center and investigate associated complications” Kim et al (2019). Abstract: The aim of the present study was to describe the procedure of totally implantable central venous port system (TICVPS) insertion performed at […]
Surveillance system for decreasing neonatal nosocomial infections
Surveillance systems are useful to reduce nosocomial infection in VLBW infants. Reduction in antibiotic and CVC use requires longer intervention time” Estañ-Capell et al (2019). Abstract: BACKGROUND: Nosocomial infection in very low birthweight (VLBW) infants is a common complication with high morbimortality. New strategies to reduce its occurrence have recently led to the development of […]
Effect of prehospital blood draws on length of stay for chest pain patients
This article provides research of cardiac biomarkers being drawn in the prehospital setting compared with the emergency department (ED) on intervals critical to the diagnosis of acute myocardial infarction” DuCharme et al (2019). Abstract: This article provides research of cardiac biomarkers being drawn in the prehospital setting compared with the emergency department (ED) on intervals […]
Information on the stability of ampicillin in total parenteral nutrition
Ampicillin (AMP) is frequently administered parenterally in critically ill patients with meningitis or endocarditis. Many of them require parallel infusion of total parenteral nutrition (TPN) admixtures. The aim of the study was to determine the physicochemical stability of AMP in TPN admixtures” Stawny et al (2019). Abstract: BACKGROUND: Ampicillin (AMP) is frequently administered parenterally in […]
Reduction of neonatal hospital-acquired infections
Central line associated blood stream infection episodes decreased from 15.2 to 2.29 episodes per 1000 catheter days (P = .004)” Flidel-Rimon et al (2019). Abstract: We instituted quality improvement program. We compare the infection rate before (2011-2012) and after (2013-2015). Central line associated blood stream infection episodes decreased from 15.2 to 2.29 episodes per 1000 catheter days […]
Prevalence and predictors of PICC-associated bloodstream infections
To evaluate the prevalence and predictors of peripherally inserted central catheter-associated bloodstream infection (PBSI) and PBSI-related death in hospitalized adult patients” Lee et al (2019). Abstract: OBJECTIVE: To evaluate the prevalence and predictors of peripherally inserted central catheter-associated bloodstream infection (PBSI) and PBSI-related death in hospitalized adult patients. MATERIALS AND METHODS: A retrospective multicenter cohort […]
Study demonstrates significant decrease in neonatal CLABSI
Although there was a significant decrease in CLABSIs and non-CLABSIs, hospital-acquired infections in preterm neonates remained high” Zipursky et al (2019). Abstract: OBJECTIVE: To determine if the reported reduction in hospital-acquired infections is due to reduced central line-associated blood stream infections (CLABSI) or non-CLABSIs. STUDY DESIGN: A retrospective cohort study design was used to describe […]
The prehospital trauma registry experience with intraosseous access
Within the registry, IO placement was relatively low (<10%) and used in casualties who received several other life-saving interventions at a higher rate than casualties who had IV access” Schauer et al (2019). Abstract: BACKGROUND: Peripheral intravenous (IV) cannulation is often difficult to obtain in a patient with hemorrhagic shock, delaying the appropriate resuscitation of […]
Prevention of venous thrombosis in paediatric acute lymphoblastic leukaemia
Secondary outcomes are central line-associated infections, patency and line replacement, superficial thrombosis, arterial events and death” O’Brien et al (2019). Abstract: Venous thromboembolic (VTE) complications in children and adolescents with acute lymphoblastic leukaemia (ALL) and T or B cell lymphoblastic lymphoma (T/B cell LL) can result not only in life-threatening acute complications but also contribute […]
Use of lidocaine on vascular pain induced by hypertonic saline infusion
To determine the analgesic efficacy and analgesic duration of lidocaine 20 mg and 40 mg on eliminating the vascular pain associated with hypertonic saline infusion” Song et al (2019). Abstract: PURPOSE: To determine the analgesic efficacy and analgesic duration of lidocaine 20 mg and 40 mg on eliminating the vascular pain associated with hypertonic saline […]
Implanted vascular access device related deep vein thrombosis in oncology patients
We sought to assess the incidence of IVAD-related upper extremity deep vein thrombosis (IVAD-related UEDVT) associated with BioFlo® IVADs (Angiodynamics, Inc.)” Suleman et al (2019). Abstract: BACKGROUND: Implanted vascular access devices (IVADs) have significantly improved the management of cancer patients. These patients are at an increased risk of venous thromboembolism and IVADs are a known […]
Spinal infections among patients with long-term central venous catheters
Spinal infections are a rare yet serious metastatic complication of bacteremia among patients with long-term central venous catheters (CVCs) for which clinicians must remain vigilant” Topan et al (2017). Abstract: Spinal infections are a rare yet serious metastatic complication of bacteremia among patients with long-term central venous catheters (CVCs) for which clinicians must remain vigilant. […]
OPAT for avoidance of hospitalisation in children
One area of increased focus for antimicrobial stewardship is outpatient parenteral antimicrobial therapy (OPAT)” Krah and Hersh (2019). Abstract: In an effort to combat antimicrobial overuse and resistance and improve patient outcomes, many paediatric hospitals have implemented antimicrobial stewardship programmes. The primary goal of these programmes is to ensure delivery of the appropriate antimicrobial at […]
Study determines the safety of IV magnesium sulfate infusion
The administration of IV infusion of MgSO4 (4 g/100 mL) in 5% dextrose over a 4-hour treatment period poses no significant deleterious effects on cardiovascular, liver, kidney, or metabolic function” Karhu et al (2018). Abstract: BACKGROUND: Magnesium (Mg) deficiency contributes to the pathophysiology of numerous diseases. The therapeutic use of Mg has steadily increased over […]
Errors in postoperative administration of intravenous patient-controlled analgesia
The findings provide valuable information that can aid in the development of policy and procedures for safer, more effective postoperative administration of IV PCA” Lee et al (2019). Abstract: BACKGROUND: Intravenous patient-controlled analgesia (IV PCA), which typically involves opioids, has become widely used in clinical settings as an effective method of pain management. Identifying errors […]
Anaphylaxis to chlorhexidine-impregnated central venous catheters
We report a case series of anaphylaxis to chlorhexidine-coated central venous catheters (CVCs) when used in cardiac surgical patients in our institution” Baird and Cokis (2019). Abstract: We report a case series of anaphylaxis to chlorhexidine-coated central venous catheters (CVCs) when used in cardiac surgical patients in our institution. Our experience, together with increasing reports […]
Impact on life cycle carbon footprint of converting from disposable to reusable sharps containers
A previous study found that converting from disposable to reusable sharps containers (DSC, RSC) reduced sharps waste stream GHG by 84% but found transport distances impacted significantly on GHG outcomes and recommended further studies where transport distances are large” McPherson et al (2019). Abstract: BACKGROUND: Sustainable purchasing can reduce greenhouse gas (GHG) emissions at healthcare […]
Haemodynamic effects of crystalloid and colloid volume resuscitation
We argue that primary as well as derived and efficiency measures should be reported and discussed when haemodynamic studies are reported involving fluid administrations” Sondergaard et al (2019). Abstract: BACKGROUND: Recent studies in haemodynamic management have focused on fluid management and assessed its effects in terms of increase in cardiac output based on fluid challenges […]
Management of hyperkalemia in the acutely ill patient
To review the mechanisms of action, expected efficacy and side effects of strategies to control hyperkalemia in acutely ill patients” Dépret et al 92019). Abstract: PURPOSE: To review the mechanisms of action, expected efficacy and side effects of strategies to control hyperkalemia in acutely ill patients. METHODS: We searched MEDLINE and EMBASE for relevant papers […]
Stability of the Infliximab following extended storage of the diluted preparation
Physicochemical and biological analyses demonstrated that the infliximab biosimilar PF-SZ-IFX was not affected by extended storage of the diluted preparations used for intravenous infusion” Vimpolsek et al (2019). Abstract: OBJECTIVE: PF-06438179/GP1111 (PF-SZ-IFX) is an infliximab biosimilar. We evaluated the extended in-use physicochemical and biological stability of PF-SZ-IFX upon preparation for intravenous infusion. METHODS: Two batches […]
Scrubbing the hub decontamination for peripheral intravenous catheter care
“This observational study (n = 108) found high compliance with “scrubbing the hub,” although scrub time was shorter than the recommended duration (average 6.1 seconds)” Slater et al (2019).
Procedure for drawing blood cultures through IV catheters
Local guidelines regarding sites for blood culture collection should reflect institution-level blood culture contamination rates for percutaneously-drawn and catheter-drawn cultures using currently available technologies that reduce contamination at both sites” Mermel (2019). Abstract: Studies published between 1999 and 2011 demonstrated increased blood culture contamination with catheter-drawn cultures compared with percutaneously-drawn cultures. Studies published between 2012 […]
Unusual mechanical complications of central venous catheterization
The use of CVC is associated with potential major complications occurring particularly during emergency situations” Katrancioglu (2019). Abstract: To present an unusual major mechanical complication of central venous catheterization (CVC). Methods: Between January 2016 and January 2017, data of the patients who underwent CVC in Cumhuriyet University in Sivas, Turkey, were retrospectively reviewed. The patients […]
Clinical impact of noble metal coated central venous catheters
There was no efficacy of BG-thin noble metal coated CVCs in reducing infectious and non-infectious complications (thrombosis) in our study” Iftikhar et al (2019). Abstract: BACKGROUND: Patients with haematological malignancies and stem cell transplant recipients are at high risk of opportunistic infections. Little international and no national data is available comparing noble metal coated versus […]
Vascular access-related blood-stream infections among Irish haemodialysis patients
Rates of access-related bloodstream infections (AR-BSI) are influenced by patient characteristics and local protocols. We explored factors associated with AR-BSI in a contemporary cohort of HD patients at a tertiary nephrology centre” Mohamed et al (2019). Abstract: BACKGROUND: Infections are the second leading cause of death and hospitalisation among haemodialysis (HD) patients. Rates of access-related […]
Meta-analysis of intracavitary electrocardiogram guidance for PICC placement
The intracavitary electrocardiogram method had a more favorable positioning accuracy versus traditional X-ray method for peripherally inserted central catheter placement in adult patients” Liu et al (2019). Abstract: BACKGROUND: Recently, intracavitary electrocardiogram technology has been applied to peripherally inserted central catheter placement and demonstrates many potential advantages. However, the tip positioning accuracy of intracavitary electrocardiogram […]
Association between intraoperative magnesium sulfate infusion and postoperative AKI
We investigated the association between intraoperative magnesium sulfate infusion and incidence of AKI after major laparoscopic abdominal surgery” Oh et al (2019). Abstract: Magnesium sulfate can be used as a co-adjuvant drug during the perioperative period and has multiple benefits. Recent evidence suggested that perioperative magnesium sulfate infusion may lower the risk of postoperative acute […]
Impact of antibacterial and antibiofilm polyurethane IV catheter coating
In this study, a novel auranofin releasing antibacterial and antibiofilm polyurethane (PU) catheter coating was developed and investigated for future use in preventing CRBSIs” Liu et al (2019). Abstract: Intravascular catheter related bloodstream infections (CRBSIs) are a leading cause of hospital-acquired infections worldwide, resulting not only in the burden of cost and morbidity for patients […]