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Novel electroosmotic pump and infusion device design

"The device was fabricated and its applicability has been demonstrated by delivering ∼1.8 mL of water at a 10 ± 2 μLmin-1 flow rate at 2 V constant applied voltage over a period of 3 h" Sreenath et al (2021).

Abstract:

A low-voltage nongassing electroosmotic pump was assembled by sandwiching a silica frit between two carbon paper electrodes that were dip-coated with a paste consisting of phosphomolybdic acid/phosphotungstic acid (PMA/PTA)-encapsulated multiwalled carbon nanotubes (MWCNTs) and Nafion. The PMA/PTA encapsulation was a combined effect of their thermomigration and nanocapillary action in MWCNTs. The encapsulated MWCNTs retained desirable redox and charge transfer characteristics of PMA/PTA. The stable voltammogram in 1 M H2SO4 solution exhibited 77% charge retention. A total of three different possible pump configurations, namely, PUMP-I = PMA//SiO2//PMA, PUMP-II = PTA//SiO2//PTA, and PUMP-III = PMA//SiO2//PTA were put together. They are in the sequence of the anode, silica frit, and cathode. All pumps showed a linear dependence on the flow rate with a minimum operating voltage of 1 V, which is well below the thermodynamic potential of water splitting. PUMP-I provided an electroosmotic flux of 43.57 μLmin-1 V-1 cm-2 that matched the requirement of an infusion device like an insulin pump. The device was fabricated and its applicability has been demonstrated by delivering ∼1.8 mL of water at a 10 ± 2 μLmin-1 flow rate at 2 V constant applied voltage over a period of 3 h. Such a wearable device can be programed to deliver model insulin or pain medication drugs for chronic diseases.

Reference:

Sreenath S, Suman R, Sayana KV, Nayanthara PS, Borle NG, Verma V, Nagarale RK. Low-Voltage Nongassing Electroosmotic Pump and Infusion Device with Polyoxometalate-Encapsulated Carbon Nanotubes. Langmuir. 2021 Jan 24. doi: 10.1021/acs.langmuir.0c03196. Epub ahead of print. PMID: 33486948.