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"Findings from this study suggest that DLT blood loss contributes to anemia in the SICU, and that the presence and duration of CVC leads to increased testing, anemia, and RBC transfusion" Adkins et al (2022).

CVC insertion predicts transfusion requirements

Abstract:

Background: Most patients in the surgical intensive care unit (SICU) have anemia and undergo extensive diagnostic laboratory testing (DLT). Consequently, patients undergo RBC transfusion, and many are discharged with anemia, both of which are associated with poorer outcomes.

Objective: To characterize DLT blood loss in the SICU.

Materials and methods: We performed a 1-year retrospective study of 291 patients admitted to a SICU. The number of draws, average volume, and estimated discard volume were recorded, along with clinical and laboratory findings.

Results: Patients who underwent greater amounts of DLT had lower hemoglobin levels at discharge (P ≤ .001). Admissions requiring central venous catheter (CVC) access (49.8%) demonstrated significantly higher DLT draws and rates of transfusion.

Conclusion: Findings from this study suggest that DLT blood loss contributes to anemia in the SICU, and that the presence and duration of CVC leads to increased testing, anemia, and RBC transfusion.


Reference:

Adkins BD, DeAnda A, Trieu JA, Polineni S, Okorodudu A, Yates SG. Central Line Access Is Predictive of Diagnostic Blood Loss and Transfusion in the Surgical Intensive Care Unit. Lab Med. 2022 Sep 2:lmac071. doi: 10.1093/labmed/lmac071. Epub ahead of print. PMID: 36053232.