Abstract:
Chronic thromboembolic pulmonary hypertension is a rare but life-threatening complication of long-term central venous catheters (CVC) in children. However, evidence in terms of potential treatment strategies and outcome data remains scarce. We describe two cases of CVC-related thrombosis (Hickman-catheter) complicated by recurrent pulmonary emboli. One patient experienced a complete thromboembolic obstruction of the right pulmonary artery with normal pulmonary pressures and the second patient suffered from a central thromboembolic obstruction of both pulmonary arteries associated with severe pulmonary hypertension. Both patients successfully underwent surgical thromboendarterectomy with deep hypothermic circulatory arrest.
Reference:Hanuna M, Pattathu J, Buech J, Kamla C, Kneidinger N, Behr J, Milger K, Veit T, Nagel M, Abicht J, Dalla-Pozza R, Fischer M, Jakob A, Hermann M, Schramm R, Rosenthal LL, Haas N, Hörer J, Hagl C, Michel SG. Case report: Central venous catheter thrombosis complicated by chronic thromboembolic disease/pulmonary hypertension in two children requiring parenteral nutrition. Front Cardiovasc Med. 2023 Jun 8;10:1198204. doi: 10.3389/fcvm.2023.1198204. PMID: 37363098; PMCID: PMC10285210.