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"However, in some cases, the results of extravasation may be evident years after NICU treatment. In this case report, we describe a rare case of physeal arrest of the distal tibia in a preterm and discuss the possible causes" Samelis et al (2022).
Rare neonatal extravasation outcome

Abstract:

Extravasation injuries are frequent complications, especially in extremely preterm neonates treated in neonate intensive care units (NICU). Depending on the type of the extravasated substance, the duration, and the amount of the leak, extravasation may result in necrosis of the soft tissues adjacent to the leak, compartment syndrome, and limb amputation. However, in some cases, the results of extravasation may be evident years after NICU treatment. In this case report, we describe a rare case of physeal arrest of the distal tibia in a preterm and discuss the possible causes.

Reference:

Samelis PV, Kolovos P, Loukas C, Sameli E, Georgiou F. Distal Tibia Epiphysiodesis After Saphenous Vein Catheterization During Treatment for Prematurity. Cureus. 2022 Jan 25;14(1):e21596. doi: 10.7759/cureus.21596. PMID: 35228954; PMCID: PMC8868030.