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"The development of novel, intense antibiotic regimes, also known as 'antibiotic eradication therapy' (AET), have contributed to increased life expectancy of CF patients" Lee and Brasher (2021).

PICC in cystic fibrosis patients

Abstract:

Cystic fibrosis (CF) is an autosomal recessive disorder causing multi-organ dysfunction. The major reason for the limited life expectancy in most patients with CF is chronic, progressive lung inflammation caused by bacterial overgrowth. The development of novel, intense antibiotic regimes, also known as ‘antibiotic eradication therapy’ (AET), have contributed to increased life expectancy of CF patients.


Reference:

Lee S, Brasher C. Peripherally Inserted Central Catheters: 100% success providing 13 day antibiotic therapy in cystic fibrosis patients aged 2 to 18 years. Paediatr Anaesth. 2021 Oct 12. doi: 10.1111/pan.14312. Epub ahead of print. PMID: 34637575.