Peripheral inotropes in critically ill children
Abstract:
Many children needing pediatric intensive care units care require inotropes, which are started peripherally prior to securing a central venous access. However, many hospitals in low- and middle-income countries (LMIC) may not have access to central lines and the vasoactive medications are frequently given through a peripheral venous access.
Aim: The aim of our study was to describe the role of peripheral vasoactive inotropes in children.
Methods: Children requiring peripheral vasoactive medications were included in this study. We retrospectively collected data at 2 time points on use and complications of peripheral vasoactive medications.
Results: Eighty-four children (51 pre-COVID era and 33 COVID pandemic) received peripheral vasoactive medications. Only 3% of children (3/84) developed extravasation injury, all of whom recovered completely.
Conclusions: Results from our study suggest that extravasation injury due to peripheral inotrope infusion is very low (3%) and it may be safely administered in children at a diluted concentration.
Reference:
Mooli RK, Sadasivam K. Peripheral Inotropes in Critically Ill Children: Is It Safe? Glob Pediatr Health. 2021 May 31;8:2333794X211022250. doi: 10.1177/2333794X211022250. PMID: 34104702; PMCID: PMC8170275.