Pediatric CVC placement and bleeding risk
Tunneled central venous catheters (CVCs) are frequently required in pediatric patients with cancer, but data on platelet transfusion thresholds in this population are limited. The commonly used threshold of 50 × 103/μL (to convert platelet count to ×109/L, multiply by 1) is based on expert opinion.1,2 This study compared bleeding complications in pediatric patients with a platelet count of 50 × 103/μL or above vs below 50 × 103/μL.
Stokes SC, Yamashiro KJ, Brown EG. Association of Thrombocytopenia With Bleeding Risk During Central Venous Catheter Placement in Pediatric Patients With Cancer. JAMA Surg. 2021 Jun 30. doi: 10.1001/jamasurg.2021.2080. Epub ahead of print. PMID: 34191023.