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"This study compared bleeding complications in pediatric patients with a platelet count of 50 × 103/μL or above vs below 50 × 103/μL" Stokes et al (2021).

Pediatric CVC placement and bleeding risk

Abstract:

Tunneled central venous catheters (CVCs) are frequently required in pediatric patients with cancer, but data on platelet transfusion thresholds in this population are limited. The commonly used threshold of 50 × 103/μL (to convert platelet count to ×109/L, multiply by 1) is based on expert opinion.1,2 This study compared bleeding complications in pediatric patients with a platelet count of 50 × 103/μL or above vs below 50 × 103/μL.

Reference:

Stokes SC, Yamashiro KJ, Brown EG. Association of Thrombocytopenia With Bleeding Risk During Central Venous Catheter Placement in Pediatric Patients With Cancer. JAMA Surg. 2021 Jun 30. doi: 10.1001/jamasurg.2021.2080. Epub ahead of print. PMID: 34191023.