Candida catheter-related bloodstream infection in patients on home PN
This review clarifies Candida CRBSI rates by species, risk factors, outcomes, and management to improve effectiveness of HPN programs” Phua et al (2019). Abstract: BACKGROUND: Catheter-related bloodstream infections (CRBSIs) are life-threatening complications for home parenteral nutrition (HPN) patients. This review clarifies Candida CRBSI rates by species, risk factors, outcomes, and management to improve effectiveness of […]
Hydrochloric acid prolongs the lifetime of central venous catheters in patients with bacteraemia
This study investigated if the additional use of hydrochloric acid (HCl) as an intraluminal lock solution may prolong the lifetime of the CVC” Ahmad et al (2019). Abstract: INTRODUCTION: Bacteraemia in adult patients undergoing treatment for leukaemia is common and associated with profound morbidity and mortality. Infections related to the use of a central venous […]
Impact of prophylactic use of taurolidine-citrate lock on CLABSI in children
The aim of the study was to evaluate prophylactic use of taurolidine-citrate (T-C) solution on the number of CRIs” Małgorzata et al (2019). Abstract: Central venous access poses a risk of developing CRIs. The aim of the study was to evaluate prophylactic use of taurolidine-citrate (T-C) solution on the number of CRIs. 97 catheters, used […]
Presence of invasive devices and risk of healthcare-associated infections
The present study evaluated the daily risk of healthcare-associated infections and sepsis (HAIS) events in pediatric intensive care unit patients with invasive devices” Bennett et al (2018). Abstract: The present study evaluated the daily risk of healthcare-associated infections and sepsis (HAIS) events in pediatric intensive care unit patients with invasive devices. This was a retrospective […]
Review of paediatricians who diagnose and manage cellulitis
There is a lack of evidence-based guidance for management of cellulitis and use of outpatient parenteral antimicrobial therapy (OPAT) in children” Ibrahim et al (2019). Abstract: There is a lack of evidence-based guidance for management of cellulitis and use of outpatient parenteral antimicrobial therapy (OPAT) in children. The only published guidelines for skin infections are […]
Investigation of complications following implantable port insertion in cancer patients
This retrospective single-institutional review was performed to identify rates of complications from port placement and potential factors associated with these events” Skelton et al (2019). Abstract: Central venous access devices, specifically implantable ports, play an essential role in the care of oncology patients; however, complications are prevalent. This retrospective single-institutional review was performed to identify […]
Clinical characteristics and outcomes of patients receiving OPAT
In our study, OPAT is found to be efficacious in saving hospitalization’s days, with a low rate of readmissions and complications and a high patients’ level of satisfaction. We therefore conclude that OPAT is feasible and safe” Briquet et al (2019). Abstract: BACKGROUND: Outpatient parenteral antibiotic therapy (OPAT) was not used in Belgium before 2013, […]
Analysis of clinical blood use in emergency blood loss patients
To explore the blood transfusion data of emergency hemorrhage patients, so as to provide the basis for improving the quality of emergency blood transfusion and guiding clinic rational blood transfusion” Jiang et al (2019). Abstract: OBJECTIVE: To explore the blood transfusion data of emergency hemorrhage patients, so as to provide the basis for improving the […]
Antibiotic-impregnated central venous catheters in the neonatal intensive care unit
It is often unclear what proportion of an improvement is attributable to each element of these care bundles and, as such, a single intervention such as antibiotic impregnation of CVCs might have too small an effect to be demonstrable” Khatami and Isaacs (2019). Extract: As Gilbert and colleagues point out,5 other infection prevention strategies in […]
Antimicrobial-impregnated central venous catheters for prevention of neonatal bloodstream infection
We found no evidence of benefit or harm associated with miconazole and rifampicin-impregnated PICCs compared with standard PICCs for newborn babies” Gilbert et al (2019). Abstract: BACKGROUND: Bloodstream infection is associated with high mortality and serious morbidity in preterm babies. Evidence from clinical trials shows that antimicrobial-impregnated central venous catheters (CVCs) reduce catheter-related bloodstream infection […]
Predicting failure of intravenous access in adults
Our aim was to validate prior need for an advanced technique to establish intravenous access as a predictor of failure to achieve access via traditional methods and to estimate the risk difference associated with this finding” Witting et al (2019). Abstract: BACKGROUND: When intravenous access cannot be established using traditional methods of inspection/palpation, advanced methods […]
IV flush volume required for peripheral intravenous catheters
“To test the feasibility of an efficacy trial comparing different flushing frequencies and volumes to reduce peripheral intravenous cannula (PIVC) failure in paediatric inpatients” Kleidon et al (2019).
CLABSI in pediatric hematology-oncology inpatients
This cross-sectional study was a retrospective review of CLABSI in inpatient pediatric hematology-oncology cases with long-term central venous catheter at the Pediatric Hematology Department from January 2013 to June 2014″ Özalp Gerçeker et al (2019). Abstract: Central line-associated bloodstream infections (CLABSIs) are still a major cause of morbidity and mortality in pediatric hematology-oncology patients in […]
Development of a unit-based safety program to prevent CLABSI
Interventions included the Comprehensive Unit-based Safety Program to improve safety culture and evidence-based bundles to prevent central line-associated bloodstream infection (CLABSI), surgical site infection (SSI), and ventilator-associated pneumonia (VAP)” Chang et al (2019). Abstract: Using a pre-post design, this study examined the impact of a multifaceted program to simultaneously improve 3 health care-associated infections and […]
Systematic review examines risk of bloodstream infection associated with implantable ports
This systematic review and meta-analysis aimed to provide evidence-based guidance to better understand the risk of central line-associated bloodstream infection (CLABSI) in cancer patients who received totally implantable venous access ports (TIVAPs) compared with those who received external central venous catheters (CVCs)” Jiang et al (2019). Abstract: OBJECTIVE: This systematic review and meta-analysis aimed to […]
Infection free midline catheter implementation reviewed
Adoption of a vascular access nurse led midline catheter program, coupled with device selection algorithms expanded the ability to select the right device for the patient, while decreasing excess central line usage without additional increased risks to the patient” DeVries et al (2019). Abstract: BACKGROUND: To reduce excess central line use and provide an option […]
Infection risk of small-bore tunneled central venous catheters
The purpose of this study is to evaluate the association of common clinical variables with small-bore tunneled central venous catheter (CVC) infection” Black et al 92019). Abstract: OBJECTIVE: The purpose of this study is to evaluate the association of common clinical variables with small-bore tunneled central venous catheter (CVC) infection. MATERIALS AND METHODS: Retrospective data […]
Effectiveness of synthetic polymer-coated peripherally inserted central catheter
Patients with advanced cancers who had indwelling PICCs were reviewed using their medical records. Three types of PICCs were compared in terms of complications and catheter failure” Takezawa et al (2019). Abstract: BACKGROUND/AIM: A peripherally inserted central catheter (PICC) is recommended for the safe administration of anticancer agents. The effectiveness of synthetic polymer-coated and non-coated […]
Article describes controlled infusion of intravenous cardiac drugs
The objective of the study is to develop an automatic drug infusion control system during cardiovascular surgery” Sowparnika et al (2019). Abstract: OBJECTIVES: The objective of the study is to develop an automatic drug infusion control system during cardiovascular surgery. MATERIALS AND METHODS: Based on the clinical drug dosage analysis, the modeling of cardiovascular system […]
Scoping review examines practices related with tourniquet use during peripheral venipuncture
This scoping review aims to map the available evidence on health professionals’ practices related with tourniquet use during peripheral venipuncture and associated microbiological contamination” Salgueiro-Oliveira et al (2019). Abstract: OBJECTIVES: During peripheral venipuncture, health professionals are recommended to use a tourniquet above the puncture site in order to potentiate venous distension. Given its characteristics and […]
Prevention of infusion phlebitis with topical heparin versus diclofenac
The association of superficial thrombophlebitis (ST) with deep-venous thrombosis varies between 6% and 44%. Thus, prevention of ST is important. The aim of this study was to compare the efficacy of topical quick penetrating solution (QPS) of heparin 1000 IU/mL versus diclofenac QPS for prevention of postinfusion ST” khileshwar and Singh (2019). Abstract: BACKGROUND AND […]
Nitroglycerin-Citrate-Ethanol catheter lock solution eradicates Candida auris biofilm
Candida auris poses emerging risks for causing severe central line associated bloodstream infections (CLABSIs). We tested in vitro, the ability of antifungal lock solutions to rapidly eradicate C. auris biofilms” Vargas-Cruz et al (2019). Abstract: Candida auris poses emerging risks for causing severe central line associated bloodstream infections (CLABSIs). We tested in vitro, the ability […]
Psychometric testing of a checklist for procedural training of peripheral IV cannulation
This checklist can be used for teaching IV placement in healthcare students in the simulation procedural training lab” Buckley et al (2019). Abstract: BACKGROUND: Nurses, medical technologists, nuclear medicine technologists, pre-hospital providers, and medical students are a few groups of healthcare learners asked to learn intravenous (IV) cannulation in their training (J Surg Educ. 69:536-43, […]
Validity of mini-fluid challenge for predicting fluid responsiveness
However, mini-fluid challenge has never been tested in patients with end-stage liver disease. This study investigated whether infusion of 150 ml albumin 5% can predict fluid responsiveness in cirrhotic patients following liver transplant” Mukhtar et al (2019). Abstract: BACKGROUND: Mini-fluid challenge is a well tested and effective tool to predict fluid responsiveness under various clinical conditions. […]
Oral versus intravenous antibiotics for bone and joint infection
The OVIVA (oral versus intravenous antibiotics for bone and joint infection) randomized study has challenged the practice of prolonged intravenous therapy” Seaton et al (2019). Abstract: Bone and joint infection contributes significantly to clinical activity within outpatient parenteral antimicrobial therapy (OPAT) services. The OVIVA (oral versus intravenous antibiotics for bone and joint infection) randomized study […]
Factors influencing the success of peripheral venous access in neonates
The aim of the study was to determine the optimal location and instruments to reduce the number of catheter insertion attempts and to increase time without complications” Monasor-Ortolá et al (2019). Abstract: PURPOSE: In neonatal units, the use of peripheral venous catheters is a commonly used technique involving risks and local complications. Catheter duration and […]
Central venous catheter-related deep vein thrombosis in pediatrics
In this study, we aim to identify the incidence of and risk factors for CVC-related DVT in this high-risk population, as its complications are highly morbid” Steen et al (2019). Abstract: BACKGROUND: Central venous catheter (CVC) use is common in the management of critically ill children, especially those with congenital heart disease. CVCs are known […]
Post mortem investigates chylothorax or leakage of total parenteral nutrition?
This case study focuses on a postmortem examination of an 84-year-old woman, hospitalized due to malnutrition and dysphagia. The left internal jugular vein was cannulated, with no post-procedural x-ray check-up of the catheter tip position. An autopsy revealed 800 ml of milky-white fluid in the left pleural cavity, raising the issue of whether the pleural […]
Researcher offers personal reflections on the development of propofol
The prominent position that propofol occupies as an anaesthetic and sedative agent is very gratifying. It is a personal honour that my involvement for many years in the discovery, development, and introduction of propofol has been recognised with my selection to receive the prestigious 2018 Lasker-DeBakey Clinical Medical Research Award” Glen (2019). Abstract: The prominent […]
Case of septic pulmonary embolism from catheter-related infection
We report a similar case but in a young adult who developed septic emboli due to DA that was caused by an infected peripherally inserted central catheter (PICC) line. Since the organism is highly susceptible to recurrent embolization, the PICC line was removed and the patient was treated successfully with an appropriate antibiotic regime” Patel […]