Abstract:
Good practice recommendations (GPRs) for outpatient parenteral antimicrobial therapy (OPAT) in the UK were first published in 2012 and 2015 for adult and paediatric OPAT, respectively, and then updated in 2019 as a combined set of recommendations for OPAT in all age groups. Since then, there has been ongoing expansion in national and global experience of OPAT. Here, we provide updated 2026 GPRs developed through a further review of the literature, expert consensus, and extensive consultation. As previously, these updated GPRs for OPAT in adults and children will support delivery of safe and effective OPAT by providing a set of quality indicators for OPAT in the UK regardless of the setting or service model.
Reference:Noble AL, Patel S, Birnie E, Dorgan E, Durojaiye OC, Emilie C, Guleri A, Green H, Hedderwick S, Hinds L, Mahoney MV, McIntyre K, Sime FB, Seddon O, Statham J, Woodley M, Gilchrist M, Seaton RA. 2026 Updated good practice recommendations for outpatient parenteral antimicrobial therapy (OPAT) in adults and children in the UK. JAC Antimicrob Resist. 2026 Apr 22;8(2):dlag044. doi: 10.1093/jacamr/dlag044. PMID: 42028542; PMCID: PMC13100498.