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"This study presents a self-administration OPAT program integrated within the pediatric antibiotic stewardship program (ASP) in a pediatric tertiary care center" Fernández-Polo et al (2022).

Pediatric self-administration OPAT program

Abstract:

Introduction: Outpatient parenteral antimicrobial treatment (OPAT) is an alternative to in-patient care in carefully selected patients. This study presents a self-administration OPAT program integrated within the pediatric antibiotic stewardship program (ASP) in a pediatric tertiary care center.

Material and methods: Descriptive, retrospective and unicentric study. Data from all patients under 20 years of age who were prescribed treatment by a pediatric unit during 2019 and 2020 were included. Data regarding number of saved beds and estimating the opportunity cost of the OPAT program for the hospital were analyzed.

Results: Fifty-seven patients received 106 episodes of treatment. Favorable clinical outcome occurred in 74.5% of the episodes. The main cause of premature interruption was unfavorable clinical outcome of the infection (37.1%). A total of 2.62 beds/day were saved, resulting in an economic benefit of 1,069,963 €.

Conclusion: A self-administration OPAT program integrated within the pediatric ASP has proven to be safe and effective and provides economic benefits.


Reference:

Fernández-Polo A, Ramon-Cortes S, Plaja-Dorca J, Bartolomé-Comas R, Vidal-Valdivia L, Soler-Palacín P; Grupo TADE-PEDIATRÍA. Impact of an outpatient parenteral antimicrobial treatment (OPAT) as part of a paediatric-specific PROA program. Enferm Infecc Microbiol Clin (Engl Ed). 2022 Aug 9:S2529-993X(22)00172-1. doi: 10.1016/j.eimce.2022.08.004. Epub ahead of print. PMID: 35961853.