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"Outpatient parenteral antimicrobial therapy (OPAT) has been shown to be feasible for people who inject drugs (PWID) in some settings" Solomon et al (2023).
OPAT for people who inject drugs in the United States

Abstract:

Injection-related infections require prolonged antibiotic therapy. Outpatient parenteral antimicrobial therapy (OPAT) has been shown to be feasible for people who inject drugs (PWID) in some settings. We report a national survey on practice patterns and attitudes of infectious diseases clinicians in the United States regarding use of OPAT for PWID.

Reference:

Solomon DA, Beieler AM, Levy S, Eaton EF, Sikka MK, Thornton A, Dhanireddy S. Perspectives on the Use of Outpatient Parenteral Antibiotic Therapy for People who Inject Drugs: Results From an Online Survey of Infectious Diseases Clinicians. Open Forum Infect Dis. 2023 Jul 15;10(7):ofad372. doi: 10.1093/ofid/ofad372. PMID: 37520410; PMCID: PMC10372854.