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Adsorption of insulin onto neonatal infusion sets – Full Text

"Within this brief report, a review of the existing literature is conducted to determine if intravenous administration of insulin should be proceeded by priming of the intravenous system, adding of albumin, or non-priming to get a stable insulin dose" Mian et al (2022).

"Within this brief report, a review of the existing literature is conducted to determine if intravenous administration of insulin should be proceeded by priming of the intravenous system, adding of albumin, or non-priming to get a stable insulin dose" Mian et al (2022).

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Adsorption of insulin onto neonatal infusion sets

Abstract:

Insulin is used to treat neonatal hyperglycaemia when blood glucose concentrations are consistently high, and to treat neonatal diabetes. Within this brief report, a review of the existing literature is conducted to determine if intravenous administration of insulin should be proceeded by priming of the intravenous system, adding of albumin, or non-priming to get a stable insulin dose. Within this literature search, we focused on experimental insulin adsorption data (in vitro studies).

Reference:

Mian P, Bolhuis MS, Maurer JM, van Stuijvenberg M. Adsorption of insulin onto neonatal infusion sets: should intravenous administration of insulin to treat hyperglycemia in preterm babies on the NICU be proceeded by priming of the intravenous system, adding of albumin, or non-priming to get to a stable insulin dose? Mol Cell Pediatr. 2022 Dec 21;9(1):20. doi: 10.1186/s40348-022-00154-y. PMID: 36542240.

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