Vascular Access Conversation - IVUPDATE Podcast from IVTEAM

"Unfortunately, during an infusion of an anthracycline chemotherapy drug, the chemotherapy drug inadvertently leaked subcutaneously. However, the patient was not treated with timely and effective drainage at the early stage of leakage, and only local hot compresses were applied" Guo and Huo (2023).
Chemotherapy drug extravasation treatment

Extract:

“A 52-year-old woman was diagnosed with invasive breast cancer at another hospital in December 2019 and had an infusion port placed on the right side of her neck for neoadjuvant chemotherapy. Unfortunately, during an infusion of an anthracycline chemotherapy drug, the chemotherapy drug inadvertently leaked subcutaneously. However, the patient was not treated with timely and effective drainage at the early stage of leakage, and only local hot compresses were applied. After two months, the local inflammatory reaction was more severe and the swelling on the right side of the face was obvious, so the local physicians performed an incision and drainage and changed the dressing for several months. This treatment process is very painful for the patient, both physically and psychologically.”

Reference:

Guo Y, Huo J. Salvage treatment after chemotherapy drug extravasation: A rare case report. Asian J Surg. 2023 Jan 17:S1015-9584(23)00076-3. doi: 10.1016/j.asjsur.2023.01.022. Epub ahead of print. PMID: 36658002.