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The aim of this study was to design, test, and validate a dual wavelength, diode laser-based, single optical fiber instrument that would accurately confirm PICC tip location at the cavoatrial junction of an animal heart, in vivo” Stringer et al (2017).

Abstract:

There are a limited number of methods to guide and confirm the placement of a peripherally-inserted central catheter (PICC) at the cavoatrial junction. The aim of this study was to design, test, and validate a dual wavelength, diode laser-based, single optical fiber instrument that would accurately confirm PICC tip location at the cavoatrial junction of an animal heart, in vivo.

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This was accomplished by inserting the optical fiber into a PICC and ratiometrically comparing simultaneous visible and near-infrared reflection intensities of venous and atrial tissues found near the cavoatrial junction. The system was successful in placing the PICC line tip within 5 mm of the cavoatrial junction.

Reference:

Stringer, B.J., Shumway, S.B., Holbrook, M.D., Copeland, C.G., Gosch, A.A. and Kück, K. (2017) Dual-wavelength Reflectance Spectroscopy of the Superior Vena Cava: A Method for Placing Central Venous Catheters at the Cavoatrial Junction. Journal of Biophotonics. August 3rd. [Epub ahead of print].

doi: 10.1002/jbio.201700018.

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