Corynebacterium species are associated with healthcare-associated infections, specifically in device implantation. Here, we report a rare case of a 44-year-old man with a totally implantable central venous access port-related Corynebacterium infection. When he developed a fever on day four of admission, vancomycin treatment was initiated. On the 11th day, the totally implantable central venous access port was removed. Corynebacterium provencense was identified from two sets of blood cultures. Vancomycin treatment was continued for 14 days after port removal, and the patient was discharged home on the 47th day. Although C. provencense infection had not been previously reported in humans, it could be treated by port removal and vancomycin administration, as demonstrated in other reports on Corynebacterium infections.

Nishigaki T, Tanaka K, Kawasaki R, Hashiguchi S, Kato H. Totally Implantable Central Venous Access Port-Associated Bloodstream Infection Caused by Corynebacterium provencense: The First Case Report. Cureus. 2024 Oct 11;16(10):e71250. doi: 10.7759/cureus.71250. PMID: 39525094; PMCID: PMC11550510.