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The healthcare-associated infection classification system is complex. Primary bloodstream infections (BSI) in patients with a central venous catheter (CVC) are defined as a laboratory-confirmed bloodstream infection (i.e., CLABSI) with or without the MBI-LCBI subcategory classification” Dandoy and Alonso (2019).

Extract:

“The healthcare-associated infection classification system is complex. Primary bloodstream infections (BSI) in patients with a central venous catheter (CVC) are defined as a laboratory-confirmed bloodstream infection (i.e., CLABSI) with or without the MBI-LCBI subcategory classification [18, 19]. Bacteria found in the bloodstream that can be directly correlated to a site-specific infection (e.g., bacteremia and urinary tract infection with Escherichia coli) are defined as secondary BSI. Over the past few years, the NHSN has required additional validation steps to categorize a BSI as a secondary infection to decrease the amount of subjectivity in primary and secondary BSI determination [18, 19]. Finally, BSI in patients that have only one positive culture from an organism considered to be a common commensal (e.g., Staphylococcus epidermidis) are classified as a contaminant, whatever the patient’s clinical course [19].”

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Reference:

Dandoy, C.E. and Alonso, P.B. (2019) MBI-LCBI and CLABSI: more than scrubbing the line. Bone Marrow Transplantation. February 26th. [epub ahead of print].

doi: 10.1038/s41409-019-0489-1.