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"The use of antibiotic therapy in the treatment of infections resulted in a low prevalence of salvage of the central venous catheter" Secco et al (2021).
Central catheter salvage in newborn

Abstract:

Objectives: to establish the prevalence of salvage of central venous catheters in newborns with bloodstream infection caused by coagulase-negative staphylococci.

Methods: retrospective cross-sectional study with 136 newborns admitted to the Neonatal Intensive Care Unit between 2011 and 2017. The total of 143 infection events undergoing antibiotic therapy were evaluated.

Results: among the 143 infection events, 39 catheters in which antibiotic therapy was used were saved and in 69 cases, the device was removed. Positive central blood culture and single lumen catheter were factors associated with salvage failure. The probability of salvage decreased with infections diagnosed from 15 days of using the catheter. Negative blood culture raised the chance of salvage by fourfold.

Conclusions: the use of antibiotic therapy in the treatment of infections resulted in a low prevalence of salvage of the central venous catheter. The probability of salvage was associated with variables of the device.

Reference:

Secco IL, Reichembach MT, Pereira HP, Silva RPGVCD. Prevalence of central venous catheter salvage in newborn with staphylococcal bloodstream infection. Rev Bras Enferm. 2021 Aug 20;74(6):e20201073. English, Portuguese. doi: 10.1590/0034-7167-2020-1073. PMID: 34431937.