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Intravenous history: First of three full text articles. This article from 1940 describes the safe preparation of intravenous solutions.


Widespread demand for an inexpensive source of safe parenteral fluids has resulted from the recognition of the importance of maintaining a positive water balance as an adjuvant in hastening convalescence. Many hospitals prepare their own solutions in an endeavor to make adequate parenteral therapy economically feasible for all their patients. Other hospitals would like to reduce the cost of providing such solutions, but are loath to undertake the preparation of parenteral solutions because they fear the occurrence of untoward allergic or febrile reactions.

Full Text


Walter, C.W. (1940) The relation of proper preparation of solutions for intravenous therapy to febrile reactions. Annals of Surgery. 112(4), p.603-625.

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