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Permanent central venous catheters (CVC), such as Port-a-Cath®, Hickmann® or PICC®, are widely used in oncology patients for cancer treatment. Thrombosis is a frequent complication that should be ruled out, as it is associated with potentially severe infection and hemodynamic consequences.

This is the case report of a male patient who was undergoing chemotherapy for colon cancer. The patient presented with an atrial mass secondary to a CVC-related organized thrombus located inside the atrial cavity. The mass was inducing a massive right-to-left intracardial shunt due to a persistent foramen ovale and signs of respiratory failure that required surgical intervention to remove the intracardial mass.


Sereno, M., Montoro, F.J., Casanova, C., Gutiérrez-Gutiérrez, G., Ojeda, J. and Casado, E.S. (2015) An unusual cause of respiratory failure in a colon cancer patient. Molecular and Clinical Oncology. 3(5), p.1152-1154.

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