Umbilical venous catheter securement using cyanoacrylate glue
Abstract:
Objective: To evaluate the role of cyanoacrylate glue in reducing dislodgement of umbilical venous catheters (UVCs).
Study design: This was a single-center, randomized, controlled, non-blinded trial. All infants requiring an UVC according to our local policy were included in the study. Infants with a UVC with a centrally located tip as verified by real-time ultrasound were eligible for the study. Primary outcome was the safety and efficacy of securement by cyanoacrylate glue plus cord-anchored suture (SG-group) vs. securement by suture alone (S-group), as measured by reduction in dislodgment of the external tract of the catheter. Secondary outcomes were tip migration, catheter-related bloodstream infection, and catheter-related thrombosis.
Results: In the first 48 hours after UVC insertion, dislodgement was significantly higher in the S-group than in the SG-group (23.1% vs. 1.5%, P<0.001). The overall dislodgement rate was 24.6% in the S-group vs 7.7% in the SG-group (P=0.016). No differences were found in catheter-related bloodstream infection and catheter-related thrombosis. The incidence of tip migration was similar in both groups (S-group 12.2% vs. SG-group 11.7%).
Conclusion: In our single-center study, cyanoacrylate glue was safe and effective for securement of UVCs, and particularly effective in reducing early catheter dislodgments.
Reference:
D’Andrea V, Prontera G, Pinna G, Cota F, Fattore S, Costa S, Migliorato M, Barone G, Pittiruti M, Vento G. Securement of Umbilical Venous Catheter Using Cyanoacrylate Glue: A Randomized Controlled Trial. J Pediatr. 2023 May 25:113517. doi: 10.1016/j.jpeds.2023.113517. Epub ahead of print. PMID: 37244573.