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"In our single-center study, cyanoacrylate glue was safe and effective for securement of UVCs, and particularly effective in reducing early catheter dislodgments" D'Andrea et al (2023).

Umbilical venous catheter securement using cyanoacrylate glue

Abstract:

Objective: To evaluate the role of cyanoacrylate glue in reducing dislodgement of umbilical venous catheters (UVCs).

Study design: This was a single-center, randomized, controlled, non-blinded trial. All infants requiring an UVC according to our local policy were included in the study. Infants with a UVC with a centrally located tip as verified by real-time ultrasound were eligible for the study. Primary outcome was the safety and efficacy of securement by cyanoacrylate glue plus cord-anchored suture (SG-group) vs. securement by suture alone (S-group), as measured by reduction in dislodgment of the external tract of the catheter. Secondary outcomes were tip migration, catheter-related bloodstream infection, and catheter-related thrombosis.

Results: In the first 48 hours after UVC insertion, dislodgement was significantly higher in the S-group than in the SG-group (23.1% vs. 1.5%, P<0.001). The overall dislodgement rate was 24.6% in the S-group vs 7.7% in the SG-group (P=0.016). No differences were found in catheter-related bloodstream infection and catheter-related thrombosis. The incidence of tip migration was similar in both groups (S-group 12.2% vs. SG-group 11.7%).

Conclusion: In our single-center study, cyanoacrylate glue was safe and effective for securement of UVCs, and particularly effective in reducing early catheter dislodgments.


Reference:

D’Andrea V, Prontera G, Pinna G, Cota F, Fattore S, Costa S, Migliorato M, Barone G, Pittiruti M, Vento G. Securement of Umbilical Venous Catheter Using Cyanoacrylate Glue: A Randomized Controlled Trial. J Pediatr. 2023 May 25:113517. doi: 10.1016/j.jpeds.2023.113517. Epub ahead of print. PMID: 37244573.