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Review of emerging CLABSI prevention perspectives

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“This article, authored by infection prevention, infectious disease, and vascular access professionals, provides emerging perspectives and technical aspects associated with the complete lifecycle of a vascular access device” Garcia et al (2024).

CLABSI prevention teaching programs for cancer patients

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“To evaluate the effectiveness of teaching-learning programs for cancer patients and/or their caregivers or family in preventing and controlling infections associated with long-term central venous access devices” Vieira et al (2024).

CLABSI rate decreased by over 40%

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“We decreased our CLABSI rate by over 40% from 2021 (1.6 per 1,000 line days) to the fourth quarter of 2022 (0.91) and kept the rate below or around the national rate (0.86) for the last three quarters of 2022” Bohan et al (2024).

Post CLABSI antimicrobial de-escalation

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“An institutional protocol was developed for the evaluation and empirical antibiotic treatment of possible CLABSIs. The potential impact of de-escalating antimicrobial therapy based on initial Gram stain and molecular identification was assessed” Beckman et al (2024).

Mycobacterium senegalense CLABSI diagnosis and management

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“Blood cultures from a permanent catheter and peripheral taken concurrently yielded Mycobacterium senegalense, identified by matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry, which established the diagnosis of CRBSI atypically presented with concurrent acute intracranial bleeding and cerebrovascular infarction at initial presentation” Badarol Hisham et al (2024).

Central venous catheter for dialysis CLABSI rates

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“Procalcitonin and erythrocyte sedimentation rate could predict the CRBSIs in this study. This study also revealed that the gram-positive bacteria were primadonna in dialysis of CRBSIs, and most of them were sensitive to aminoglycosides” Chandra et al (2024).

CLABSI rates in Swedish Covid-19 patients – Full Text

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“This study revealed a low incidence of catheter-related bloodstream infection in the coronavirus disease 2019-intensive care unit, thus suggesting that coronavirus disease 2019 is not a risk factor for catheter-related bloodstream infection and indicating the high resilience of well-established routines aimed at catheter-related bloodstream infection prevention” Lunnemar et al (2024).

CRBSI central catheter salvage – Full Text

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“Catheter salvage in S aureus CRBSIs in children receiving HPN can be attempted after careful consideration by a multidisciplinary team in an HPN expertise center” Demirok et al (2024).

11-component CLABSI reduction bundle

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“We implemented the INICC multidimensional approach, incorporating an 11-component bundle, in 122 ICUs spanning nine Asian countries. We computed the CLABSI rate using the CDC/NSHN definition and criteria” Rosenthal et al (2024).

PICC related CLABSI in neonates – Full Text

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“Low birth weight, premature delivery, off-site nutrition, long catheterization time, and 5-minute APGAR score ≤7 are independent risk factors for catheter-related bloodstream infection in neonates with peripherally inserted central venous catheters. The pathogenic bacteria are fungi and multidrug-resistant bacteria” Zhang et al (2024).

CLABSI burden outside acute care hospitals

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“Surveillance is required to understand the burden of CLABSI in the community to identify targets for CLABSI prevention initiatives outside acute care settings” Oladapo-Shittu et al (2024).

CLABSI diagnosis and central line salvage

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“Central line salvage can be safely attempted for many infections in patients with intestinal failure, leading to vascular access preservation” Larson-Nath et al (2024).

Bacterial isolates from positive paired blood cultures – Full Text

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“This case report indicates consideration should be given to reporting whether bacteria have been identified at either species or strain level if differential time to positivity or differential quantitative blood cultures are used to define catheter or cannula bloodstream infection” Austin et al (2024).

The Canadian Nosocomial Infection Surveillance Program – Full Text

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“Significant rate increases were observed in adult mixed intensive care unit CLABSIs (1.08-2.11 infections per 1,000 line days, p=0.014) while decreases were observed in SSIs following knee arthroplasty (0.34-0.27 infections per 100 surgeries, p=0.05)” Canadian Nosocomial Infection Surveillance Program (2023).

CLABSI rates during the COVID-19 period – Full Text

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“Pooled data for central line-associated bloodstream infections (CLABSIs) indicated a significant increase during the COVID-19 period, but one study reported an increase in CLABSI incidence” Teus et al (2024).

Knowledge and skills in CLABSI prevention – Full Text

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“ur validated and clinically tested tool could facilitate the transfer of ICU nurses’ knowledge and skills learning in VAP and CRB prevention to critically ill patients, decreasing infection rates and, therefore, improving patient safety” Raurell-Torredà et al (2024).

Infection risk in neonates with intestinal failure

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“Neonates with intestinal failure (IF) are at risk for infection due to central venous access, and intestinal surgery. Infection can cause systemic inflammation and sepsis, potentially affecting growth” Wu et al (2024).

CVC colonization rate in patients with severe burns

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“The CVC colonization rate in patients with severe burns and routine CVC changing was not high. Lengthening the CVC duration might be attempted in patients at a lower risk of catheter-related BSI although further prospective studies are necessary” Jeon et al (2024).

CLABSI reduction in a low middle-income country – Full Text

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“Our multi-faceted approach using the CUSP model was associated with reduced CLABSI-associated morbidity and mortality in resource limited settings. Our findings suggest that higher attendance rate (>80%) at meetings may be necessary to achieve sustained effects post-intervention” Latif et al (2024).

CLABSI related complications – Full Text

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“This 2-year retrospective single-center study of patients with CRBIs from a tertiary care hospital examined the hematogenous complications associated with CRBIs according to patient characteristics, central venous catheter (CVC) types, and causative bacteria” Carolle Ngo Bell et al (2024).

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