Nurse coordinated OPAT outcomes – Full Text
“A structured, nurse-driven outpatient parenteral antimicrobial therapy (OPAT) program within an academic healthcare system was associated with reduced odds of 60-day unplanned OPAT readmissions and costs after hospital discharge” Deng et al (2024).
Adverse events associated with peripherally administered norepinephrine
“Extravasation of peripherally administrated norepinephrine in the perioperative period occurred at similar rates as in previous studies in critically ill patients. In our setting, where we regularly inspected the infusion site and shifted site in case of swelling or paleness of skin, we observed no case of severe adverse events. Given that severe adverse events were absent, the potential benefit of this preventive approach requires confirmation in a larger population” Christensen et al (2024).
Fatal superior vena cava rupture during catheter exchange
“In this report, we describe a case of a 25-year-old woman who presented with an extensive history of multiple dialysis access failure for left internal jugular vein central venous tunneled catheter exchange. The procedure was complicated by a fatal superior vena cava rupture likely related to the dislodgment of the guidewire causing perforation into the pericardium space with subsequent cardiopulmonary collapse” Ali et al (2024).
Intracavitary ECG for PICC placement in patient with PLSVC – Full Text
“Intracavitary electrocardiogram (IC-ECG) guidance is widely used for peripherally inserted central catheter (PICC) placement. The P wave variation has rarely been reported in persistent left superior vena cava (PLSVC)” Zhang and Zhao (2024).
Integrated short peripheral intravenous cannula failure rates – Full Text
“This systematic review and meta-analysis aimed to analyze randomized controlled trials (RCTs) and quasi-randomized studies in hospitalized patients, analyzing the risk of overall catheter failure as well as the risk of each type of complication (occlusion, infiltration, thrombophlebitis, and dislodgement) for ISPCs compared to non-integrated SPCs” Gidaro et al (2024).
OPAT experience with dalbavancin – Full Text
“This report adds to clinical experience with dalbavancin for off-label indications whilst further validating its role in ABSSSI. Dalbavancin as primary therapy in deep-seated infections merits investigation in formal clinical trials” McSorley et al (2024).
Interventions for UEDVT in cancer patients – Full Text
“Therapeutic anticoagulation was not associated with a reduction in the incidence of recurrent VTE or increase the incidence of bleeding in adult cancer patients following a CVC-associated DVT diagnosis” Ngo et al (2024).
Home care of PICC – Full Text
“Adults living with a PICC at home report a broad range of supportive care needs. In addition to practical and information needs, health consumers may also require support to accept living with a device inside their body and to assume responsibility for the PICC” Sharp et al (2024).
Tunneled central venous access in children – Full Text
“Ultrasound-guided percutaneous insertion was considered to be a safe and effective technique for the insertion of central venous catheters. Our study also demonstrated a decrease in operating times when performed by operators with increasing expertise, increased preservation of the diameter of the venous lumen, and no increase in complication rates when the ultrasound-guided technique was selected” Kouna et al (2023).
Dalbavancin use in cardiovascular prosthetic infections – Full Text
“Because of pharmacokinetic individual variability, dalbavancin TDM-guided administration could improve clinical outcomes by individualizing dosing and selecting dosing intervals. This case series seems to suggest a promising role of long-term suppressive dalbavancin treatment for difficult-to-treat cardiovascular prosthesis infection, also with limited surgical indications” Gallerani et al (2023).
Misplaced CVC results in emphysematous thrombophlebitis – Full Text
“Emphysematous thrombophlebitis is a fulminant and life-threatening CVC-BSI associated with thrombosis and gas formation in the vein. A misplaced CVC may facilitate the development of emphysematous thrombophlebitis. POCUS can easily identify the artifacts produced by gas and thrombosis, facilitating rapid diagnosis at the bedside” Chen et al (2023).
Infusion phlebitis published studies review – Full Text
“Phlebitis secondary to vascular access is one of the most frequent complications in hospital care. This study aims to evaluate the scientific activity related to this complication through a bibliometric analysis” Torné-Ruiz et al (2023).
CVC blood sampling in the presence of AV fistula – Full Text
“It seems most likely in our case that the distal CVC lumen was situated sufficiently close to the fistula to allow aspiration from an arterial, well-oxygenated stream of blood” Evans and Hall (2023).
Defaulting to single lumen PICC orders – Full Text
“Defaulting the order for peripherally inserted central catheters (PICCs) placement to single lumen increased proportion of single-lumen insertions over total insertions from 42/126 (33%) to 57/104 (51)%” Trautman et al (2023).
Preventing healthcare-associated MRSA bacteremia – Full Text
“Overall, HA-MRSA-B incidence decreased from 1.72 cases/10000BD in 2008 to 0.18/10000BD in 2019; a reduction of almost 90%. Intravenous device interventions were also associated with a reduction of methicillin-sensitive Staphylococcus aureus (MSSA) bacteremia rates” Borg et al (2023).
IV fluid administration rate and acute kidney injury – Full Text
“The foundation of early septic shock management includes early fluid resuscitation, but the association between fluid resuscitation rates and kidney outcomes remains unclear. This investigation examines the association between fluid resuscitation rate and AKI recovery” Reddy et al (2023).
Microplastics released from disposable PVC infusion sets – Full Text
“Our findings indicate PVC MNPs can enter the blood vessel directly with the infusion fluids during intravenous infusion and the PVC MNPs exposure risk towards patients deserves more attention” Zheng et al (2023).
Effectiveness of ceftaroline-F and ceftobiprole-M – Full Text
“The fifth-generation cephalosporins, ceftaroline-F and ceftobiprole-M, are safe and effective in real life, with no difference between them in health outcomes” Arnés García et al (2023).
CLABSI rates in low-middle income countries
“We implemented a multidimensional approach, incorporating an 11-element bundle, education, surveillance of CLABSI rates and clinical outcomes, monitoring compliance with bundle components, feedback of CLABSI rates and clinical outcomes, and performance feedback in 316 ICUs across 30 low- and middle-income countries (LMICs)” Rosenthal et al (2023).
Electronic chemotherapy order verification checklist
“This study demonstrates the effectiveness of implementing the ECOV checklist in increasing the rate of pharmacy reported medication errors” Wat et al (2023).
Chemotherapy infusion site induration – Full Text
“Selecting the vein with 3.7 times higher diameter than the catheter diameter for the catheterization site may help prevent induration on the next treatment day” Abe-Doi et al (2023).
Removal of stuck tunnelled dialysis catheter
“Tunnelled central venous dialysis catheters can usually be removed easily. However, their removal can become rarely complicated requiring more invasive techniques. We report a case in which cardiopulmonary bypass and repair of great veins was required for safe removal” Bakr and Ali (2023).
Vascular Access and IV Therapy Resource
PICC CLABSI risk single center research study
“This study was carried out to understand PICC-related complications, specifically infections and causal pathogens, in a tertiary care hospital in Kerala, South India” Arjun et al (2023).
Relieving pain associated with IV port needle insertion
“EMLA cream is a safe and effective way to alleviate pain during non-coring needle insertion in TIAP and enhance the overall comfort of patients. We recommend applying EMLA cream 1 h before needle insertion of TIAP, especially in patients having needle phobia or high pain scores from previous non-coring needle insertion” Shi et al (2023).
Impact of lock solutions on polyurethane central venous catheters
“The impact of ethanol locks on the mechanical performances of central venous catheters was compared to that of aqueous-based locks. Several mechanical tests were performed to evaluate catheter behavior: kinking radius measurements, burst pressure, and tensile tests” Khzam et al (2023).
OPAT adverse safety events review – Full Text
“Adverse safety events and OPAT-related unscheduled care occurred often in our cohort. A structured OPAT program that includes ID pharmacist antibiotic reconciliation may reduce rates of ADEs” Billmeyer et al (2023).
Impact of long-term CVC use on silicone catheter strength
“In vivo long-term used silicone catheters showed significantly lower ultimate strength than unused ones. It is likely that in situ altering changes the mechanical properties of catheters and may potentially lead to failure” Guerreiro et al (2023).
Safety of OPAT for infective endocarditis treatment
“OPAT can be used safely in patients with IE, even in selected cases with complicated or difficult-to-treat infections” Campbell et al (2023).
Top 10 OPAT publications in 2022 – Full Text
“The top 20 OPAT articles published in 2022 were reviewed by a group of multidisciplinary OPAT clinicians. This article provides a summary of the “top 10″ OPAT publications of 2022” Childs-Kean et al (2023).
Reducing blood sample hemolysis in the emergency department – Full Text
“The burden of hemolysis in blood samples taken from IV cannulae can be effectively reduced with the use of manual aspiration using the S-Monovette® blood collection system as compared to BD-Vacutainer” Omar et al (2023).
PICC site associated necrotizing fasciitis – Full Text
“In addition to medical treatment and prompt surgical debridement, we used dialkyl carbamoyl chloride-coated dressing and povidone-iodine sugar ointment for antiseptic dressings and successfully treated neonatal necrotizing fasciitis with gas gangrene caused by peripherally inserted central catheter infection with Citrobacter koseri” Okamoto et al (2023).
Management of child procedural pain Cochrane review – Full Text
“Therefore, a comprehensive and systematic review of pain management strategies is integral to appropriate infant pain management. This is an update of a previously published review update in the Cochrane Database of Systematic Reviews (2015, Issue 12) of the same title” Pillai Riddell et al (2023).
Continuous or intermittent meropenem administration – Full Text
“Compared with intermittent administration, continuous administration of meropenem may improve clinical outcomes” Monti et al (2023).
Needleless connector microbial contamination
“The aim of this study was to determine bacterial contamination of needleless connectors before and after disinfection to assess the risk for the point of catheter-related bloodstream infections” Akbıyık et al (2023).
Subclavian artery iatrogenic injury during central venous access
“This case describes the management of a central venous catheter placed through the internal jugular vein into the subclavian artery via a supraclavicular puncture” Palesy et al (2023).
Virtual reality for procedural pain reduction in pediatrics – Full Text
“Virtual reality (VR) is a relatively new intervention that can be used to provide distraction during or to prepare patients for IV injections, however, so far no meta-analysis has been conducted to examine the evidence regarding the effectiveness of VR in reducing pain in pediatric IV injection” Jenabi et al (2023).
IV fluid therapy for critically ill adults with sepsis
“Although optimal fluid management in patients with sepsis remains uncertain, clinicians should consider the risks and benefits of fluid administration in each phase of critical illness, avoid use of hydroxyethyl starch, and facilitate fluid removal for patients recovering from acute respiratory distress syndrome” Zampieri et al (2023).
Landmark-guided CVAD insertion in low-resource settings
“Here, we report our experience with the reliability and consistency of anatomic landmark-guided technique for Central Venous Access Device (CVAD) insertion in a low-resource setting” Kaul et al (2023).
Platelet transfusion before CVC placement
“Transfusion guidelines regarding platelet-count thresholds before the placement of a central venous catheter (CVC) offer conflicting recommendations because of a lack of good-quality evidence. The routine use of ultrasound guidance has decreased CVC-related bleeding complications” van Baarle et al (2023).
Intravenous drug errors in critically ill patients
“The study reported high frequency of IV medications preparation and administration errors. Nurse education level, and experiences were influenced the total errors” Hamadalneel et al (2023).
Development of the Infection Prevention Appraisal Scale – Full Text
“The Infection Prevention Appraisal Scale demonstrates sound psychometric properties supporting a unidimensional measure of self-efficacy to medical asepsis in care situations” Lindberg and Lindberg (2023).
All cause hospital-onset bacteremia reporting metric
“If the HOB metric were to be used in lieu of CLABSI, large tertiary care health systems that house sicker patients may be unfairly financially penalized for caring for more medically complex patients” Stack et al (2023).
Probiotic-associated central venous catheter bloodstream infection
“In ICU patients with central venous catheters, the risks of probiotic-associated central venous catheter bloodstream infection and death outweigh any potential benefits of probiotic administration” Mayer et al (2023).
Disinfection of ultrasound transducers used on skin – Full Text
“This study compared the effectiveness of LLD to HLD on US transducers contaminated with microorganisms from skin” Peters et al (2023).
Risk prediction model for PICC-related venous thrombosis – Full Text
“The independent risk factors for PICC-related venous thrombosis are screened out, including catheter tip position, plasma D-dimer elevation, venous compression, history of thrombosis and history of PICC/CVC catheterization, and a nomogram prediction model with good effect is constructed to predict the risk of PICC-related venous thrombosis” Chen et al (2023).
Quality improvement initiative to reduce NICU CLABSI rates – Full Text
“Reducing CLABSI rate is necessary to improving newborn quality of care and outcome. Our bundles were successful in drastically reducing and sustaining a low CLABSI rate. It was even successful in achieving a zero CLABSI unit for 2 years” Al Bizri et al (2023).
Minimally invasive capillary blood sampling – Full Text
“We expect that microneedles will prove to be a preferred option for paediatric blood collection. The ability of microneedles to collect a capillary blood sample without pain will improve paediatric healthcare outcomes” Hoffman et al (2023).
End-of-life care preferences of the Asian elderly – Full Text
“Regardless of scenario, cardiopulmonary resuscitation (CPR) had the lowest score, indicating that older adults considered it a less desirable medical treatment. By contrast, antibiotics and intravenous infusions had the highest scores, indicating that older adults tended to prefer them” Ke et al (2023).
First-dose antimicrobial reactions in OPAT patients – Full Text
“These findings suggest it would be reasonable to forgo monitoring for most patients receiving first-dose intravenous antimicrobials outpatient” Kovacik et al (2023).
Economic burden of CRBSI – Full Text
“The medical costs of ICU patients were closely related to the incidence of CRBSI. Imperative measures are needed to reduce CRBSI in ICU patients” Zhang et al (2023).
Outpatient intravenous diuresis review – Full Text
“OP IV diuresis appears safe and effective for rural HF patients, potentially decreasing mortality rates and healthcare expenses while mitigating rural-urban disparities” Pathangey et al (2023).
Pain during PICC insertion in preterm infants – Full Text
“To evaluate whether warm povidone-iodine (PI) application before peripherally inserted central catheter (PICC) placement eased pain related to the procedure in premature infants and reduced the duration of the procedure and the number of attempts” Yavanoglu Atay et al (2023).