National Association of Neonatal Nurses PICC guidelines
“The NANN PICC Guideline has served as a respected resource for vascular access protocol development in neonatal intensive care units around the world. This most recent edition continues as the foundational resource for protocols, policies, and procedures development for nurses and other clinicians inserting PICCs and managing neonates and infants with PICCs around the world” Sharpe et al (2024).
Implantable port flip rate in children – Full Text
“The CVP inversion rate was 4.6% (n = 7/153), equivalent to 0.08 × 1,000 catheter-days. The inversion rate was significantly higher in the younger group (under two years old, 11.2%) than in the older group (≥two years old, 1.0%) according to the univariate analysis (p = 0.00576)” Koretsune et al (2024).
Dwell time for peripheral IV catheters – Full Text
“Up to 1/5 of peripheral intravenous catheters are lost within the first 24 h after their insertion, with most of them placed suboptimally. A properly functioning PIVC appears to be crucial for antimicrobial treatment” Piekiełko et al (2024).
Central venous catheter insertion and management audit results – Full Text
“To assess the compliance with French guidelines for the prevention of central venous catheter (CVC)-related infections in two university hospitals” Khanafer et al (2024).
PICC colonization with multi drug-resistant microorganisms and CLABSI – Full Text
“The findings of the present study suggest that CLABSIs caused by MDROs in PICCs are associated with a shorter mean catheter dwell time compared to those caused by non-MDROs, underscoring the importance of considering infections by MDROs when evaluating PICC dwell times” Pitiriga et al (2024).
Antimicrobial activity against bacterial biofilms on CVC – Full Text
“For the first time, a new dynamic in vitro model was constructed to evaluate the antimicrobial activity against bacterial biofilms on central venous catheters (CVCs) on both external surface and internal surface” Fang et al (2024).
Implantable port fracture case study
“This case underscores the importance of early identification and interdisciplinary collaboration in managing port catheter fractures and migrations, even in the absence of typical symptoms” Chandna et al (2024).
Pharmacy-led neonatal CLABSI reduction initiative
“Pharmacists and pharmacy technicians received training on how to properly prime tubing, document when a patient received a new central line, document if a central line was removed, and record when new tubing was due based on a department policy” Zackeroff et al (2024).
Intraosseous access in adults during out-of-hospital cardiac arrest – Full Text
“To compare the effectiveness of intraosseous versus intravenous vascular access in the treatment of adult patients with out-of-hospital cardiac arrest” Ko et al (2024).
Ultrasound-guided supraclavicular approach for tunneled CVC insertion
“We examined the clinical outcomes of tCVC insertions performed by junior residents through UGSC of the BCV” Iwamoto et al (2024).
Measuring venous oxygen saturation from midline catheters
“Midline catheters are inserted via a peripheral vein above the antecubital fossa and provide a safe alternative to CVCs. This study aimed to determine the equivalence of ScvO2 and midline catheter oxygen saturation (SmO2) in critically ill patients” Kim et al (2024).
IV lock solution in paediatric oncology patients – Full Text
“Taurolidine-citrate(-heparin) lock solutions (TCHL) are suggested as a promising and safe method for the prevention of central line-associated bloodstream infections (CLABSI)” van den Bosch et al (2024).
Elastomeric infusion pumps for colorectal cancer chemotherapy – Full Text
“The selection of portable elastomeric infusion pumps should consider the preferences of patients with colorectal cancer, as these devices have the potential to enhance their quality of life” Yamada et al (2024).
Preventing biofilm formation and adhesion – Full Text
“We are attempting to assess the effect of a new therapeutic agent, N-acetylcysteine (NAC), on adhesion and biofilm formation in Candida parapsilosis clinical strains” Zuo et al (2024).
Catheter-associated deep venous thrombosis in adults with inflammatory bowel disease – Full Text
“Our study shows that CADVT risk is nearly three times higher with PICCs compared with tunneled catheters. We recommend tunneled catheter placement for patients with IBD who require HPN infusion greater than 30 days” Siddiqui et al (2024).
Canadian nosocomial infection surveillance program – Full Text
“A significant rate increase was observed in adult mixed intensive care unit CLABSIs (1.07-1.93 infections per 1,000 line days, p=0.05) and a non-significant rate increase was observed in SSIs following knee arthroplasty (0.31-0.42 infections per 100 surgeries, p=0.45)” Canadian Nosocomial Infection Surveillance Program (2024).
Barriers related to implementing CLABSI prevention guidelines – Full Text
“Critical care nurses exhibited low knowledge of CLABSI prevention guidelines, with compliance reaching an acceptable level. Despite the higher perceived barriers, the nurses demonstrated a positive attitude. Nurses with greater knowledge and positive attitudes displayed higher compliance levels” Alqalah (2024).
OPAT structure review from multiple countries – Full Text
“This paper presents a comparative analysis of Outpatient Parenteral Antimicrobial Therapy (OPAT) structures and delivery options across different countries” Reidy et al (2024).
Pediatric infusion extravasation – Full Text
“Improving nursing measures and enhancing nursing management can reduce the incidence of fluid extravasation and infusion set dislodgement in pediatric patients, improve children’s compliance and satisfaction of their families, and reduce family complaints” Lv et al (2024).
Umbilical venous catheter malposition – Full Text
“We present a rare case of umbilical venous catheter (UVC) malposition complicated with respiratory distress, pleural effusion, and acute kidney injury” Simreen et al (2024).
Association between HAI and hospital financial performance – Full Text
“This study demonstrates that specific HAIs may be associated with increased hospital expenses. Proactively targeting these infections through tailored interventions may lead to reduced hospital costs, improved financial performance, and economic stability” Beauvais et al (2024).
StatSeal catheter exit site protection evaluation trial
“The findings demonstrate StatSeal’s effectiveness in improving patient outcomes by reducing exit site bleeding and associated complications, enhancing the efficiency of vascular access maintenance and potentially lowering associated healthcare costs” Hastings and Barton (2024).
Vascular Access and IV Therapy Resource

VTE prophylaxis in cancer patients with CVC – Full Text
“The introduction of direct oral anticoagulants (DOACs), with its proven efficacy and safety in multiple clinical indications, have renewed the attention to VTE prophylaxis in cancer patients with CVC” Abdel-Razeq and Al-Jaghbeer (2024).
CVC tip location study – Full Text
“A microbubbles test (MBT) can be used to confirm correct CVC positioning. However, there is serious doubt regarding whether the currently applied threshold of a 2 s push-to-bubbles time (PTB time) for rapid atrial swirl sign (RASS) in an MBT is reliable and accurate” Ley et al (2024).
11-component CLABSI reduction bundle
“We implemented the INICC multidimensional approach, incorporating an 11-component bundle, in 122 ICUs spanning nine Asian countries. We computed the CLABSI rate using the CDC/NSHN definition and criteria” Rosenthal et al (2024).
Antimicrobial dosing recommendations for obese patients
“This is a comprehensive review of the dosing of different types of antimicrobials (antibiotics, antifungals, antivirals, and antituberculosis drugs) in obese patients, where the literature on PK and possible dosing strategies in obese adults was critically assessed” Castro-Balado et al (2024).
Early blood administration by Emergency Medical Services – Full Text
“Prehospital blood programs must be thoughtfully planned, have multiple safeguards, ensure adequate training and credentialing processes, and be responsible stewards of blood resources” Levy et al (2024).
Neonatal central venous catheterization protocol
“Recently, the GAVeCeLT has proposed a protocol called SICA-PED (i.e. Safe Insertion of Central Access in Pediatric patients) and includes seven evidence-based strategies” Spagnuolo et al (2024).
Oncology infusion center daily nurse staffing ratio
“This study assessed three acuity models across multiple centers to determine whether acuity was superior to patient volumes or patient hours in predicting the number of nurses needed to care for scheduled patients in an OIC, as well as the effect on objective metrics of missed nurse lunch breaks and patient wait times” Tobias et al (2024).
Evolution of intravenous medication errors
“This narrative review demonstrates a growing interest in systems-based risk management for intravenous drug therapy and in introducing new technology, particularly smart infusion pumps and preparation systems, as systemic defenses” Kuitunen et al (2024).
Hospital-acquired bloodstream infections in cancer patients
“We summarise strengths and weaknesses of commonly used surveillance definitions and denominators in the setting of cancer care; existing surveillance practice; epidemiology of haBSI and CLABSI; prevention strategies; and current knowledge gaps” MacPhail et al (2024).
Impact of CVC removal on neonatal CLABSI – Full Text
“Staphylococcus capitis is an increasingly prevalent pathogen in the neonatal setting, frequently causing central-line-associated bloodstream infections (CLABSIs) that can be difficult to eradicate. Central venous catheter (CVC) removal versus in situ treatment with CoNS CLABSIs is a controversial treatment strategy with no clear consensus” Sala et al (2024).
Fillable elastomeric pump technology
“Due to advances in elastomeric pump technology, there are now devices available that can be filled with intravenous (IV) therapy at the bed or chair side. These devices are safe, reliable and enable the patient to be mobile when having their infusion” Barton et al (2023).
Parenteral nutrition as a vehicle for drug delivery
“This review focuses on the utilization of Total Parenteral Nutrition (TPN) as a method for delivering drugs. It discusses the benefits and difficulties associated with its commercial application and offers suggestions for future research endeavors” Bakrey et al (2024).
What is the effect of taurolidine on the time-to-positivity of blood cultures – Full Text
“In the presence of taurolidine, the TTP was considerably delayed or vials even remained negative as compared to vials containing heparin, citrate or NaCl. This effect was dose-dependent. The delayed TTP was much less pronounced in the presence of blood, but still notable” van den Bosch et al (2024).
Wrong-route drug administration errors – Full Text
“Oral drug formulations and enteral feeds may inadvertently be administered intravenously. Intravenous medications may be inadvertently administered intra-arterially. These examples of wrong-route drug administration errors have the potential to cause significant organ dysfunction and even death” Taylor and Blockman (2023).
PICC related CLABSI in neonates – Full Text
“Low birth weight, premature delivery, off-site nutrition, long catheterization time, and 5-minute APGAR score ≤7 are independent risk factors for catheter-related bloodstream infection in neonates with peripherally inserted central venous catheters. The pathogenic bacteria are fungi and multidrug-resistant bacteria” Zhang et al (2024).
Home parenteral nutrition best practice examples – Full Text
“This article is based on presentations and discussions held at the International Safety and Quality of PN Summit, providing insights into aspects of home PN (HPN) and examples of good HPN practice” Kumpf et al (2024).
Intravenous protection device to prevent self-injection – Full Text
“The misuse of medical IV access is a potential source of prolonged hospitalizations and fatal overdoses nationwide. On two separate occasions, patients were found dead in our ED bathroom after overdosing by accessing their IV site for self-injection. These events prompted the development of the IV SafeLock prototype” Bragg et al (2024).
Needlestick injuries in medical school – Full Text
“The aim was to determine numbers and causes of NSIs as well as the frequency with which medical students report NSIs in the final stages of study” Keicher et al (2024).
Microplastics from neonatal parenteral nutrition circuit – Full Text
“The leaching of particles from plastic health care equipment in the blood of intensive care patients has been associated with several health risks, and as such, similar health risks could occur with leaching of microplastics” Vercauteren et al (2024).
CIMUS consensus statement on POCUS competencies – Full Text
“The CIMUS group recommends 28 competencies be considered mandatory and 3 as optional for internal medicine physicians performing POCUS guided thoracentesis, paracentesis, and CVC placement” Canadian Internal Medicine Ultrasound (2024).
Catheter-related superior vena cava syndrome case study – Full Text
“Here we present a case of a patient on maintenance hemodialysis who developed catheter-related superior vena cava syndrome and subsequently suffered from hemorrhagic pericardial tamponade after undergoing percutaneous transluminal angioplasty and stenting” Zhao and Wang (2024).
Ultrasound guided implantation of venous access ports – Full Text
“The aim of this study was to present demographic information of patients undergoing totally implantable venous access port (TIVAP) implantation and to investigate the rates of early and late complications, assessing the benefits of performing the procedure under US guidance” İlhan et al (2024).
PICC insertion in patients with chronic kidney disease
“Peripherally Inserted Central Catheters play an increasingly important role in Central Venous Access Devices. However, the use of these devices should be carefully considered in specific situations such as central catheterisation in patients with chronic kidney disease” Ajello et al (2024).
Midline catheter insertion simulation-based learning method
“This study aimed to propose and assess a simulation-based learning method for the placement of MCs in novice practitioners” Slosse et al (2024).
Pediatric hemolyzed laboratory samples in ED – Full Text
“Hemolysis in the pediatric ED population is a frequent complication that occurs at similar rates as in adults. PIVCs placed in the hand/wrist were associated with higher odds of hemolysis compared to those placed in the antecubital fossa” Mielke et al (2024).
Limb length discrepancy after intraosseous line placement
“We will present the case of a 6-year-old girl who presented with a 3-cm limb length discrepancy after intraosseous line placement at age 14 months without other known history of trauma or infection to account for the growth arrest” Kleinsmith and Kowalski (2024).
Elastomeric pump use in home-based palliative care
“We aimed to evaluate the cost associated to the repeated filling of EIP used in a home-based palliative care team” Simões et al (2024).
Peripheral intravenous catheter dwell time
“This review examines the differences in dwell times between traditional PIVCs and ultrasound-guided PIVCs (USGPIVCs) and their implications for patient care” Harrell (2024).
Health-related quality of life in OPAT patients
“OPAT is associated with improved patient-reported quality of life and facilitates early return to work or school. Nevertheless, it is crucial to closely monitor patients with a lower baseline quality of life to optimize their overall OPAT experience” Durojaiye and Kritsotakis (2024).
Reducing umbilical catheter migration – Full Text
“This study evaluates the effectiveness of a novel device, LifeBubble, in reducing umbilical cord catheter (UC) migration and associated complications in neonates” Perl et al (2024).