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OPAT services for people who use drugs – Full Text

“OPTIONS-DC is a multidisciplinary care conference developed in 2018 that utilizes a standardized conference tool led by outpatient parenteral antimicrobial therapy (OPAT) registered nurses (RNs) to guide treatment and discharge planning while focusing on harm reduction, ethical principles, and patient preferences” Douglass et al (2025).

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Peripheral venous catheter fixation

“The study was carried out to compare the effect of transparent covers and elastic fixation bands used in peripheral venous catheter fixation on microbiological colonisation in patients in intensive care” Orhan and Goktas (2025).

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Staphylococcus aureus infection in hospitalized infants

“Historically, Staphylococcus aureus has been a leading cause of morbidity and mortality in the neonatal intensive care unit (NICU). The current incidence and attributable mortality of late-onset invasive S aureus infection in hospitalized infants is unknown” Jennings et al (2025).

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Late CVC complications in cancer patients – Full Text

“The COVID-19 pandemic negatively impacted catheter management in cancer patients, increasing late complications. The post-pandemic decline highlights the importance of consistent care, infection prevention, remote monitoring, and stronger healthcare resilience to reduce risks in future crises” Lo Cascio et al (2025).

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Vascular Access and IV Therapy Resource

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Central venous catheter malposition correction

“Malposition of central venous catheter is a notable technical complication and often need retrieval to avoid further complications. We present a retrospective assessment of case series and literature review of the safety and efficacy of open and endovascular procedures performed to retrieve malpositioned central venous catheters in the subclavian artery” Shehata et al (2025).

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Antimicrobial-induced neutropenia in OPAT

“Data regarding the incidence, onset, and management of complex outpatient antimicrobial therapy-induced neutropenia (COIN) are limited, and pharmacist involvement in COIN management has not been reported” Edwards et al (2025).

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Preventing biofilm formation on central venous catheters – Full Text

“The aim of this study was to evaluate the activity of a cationic arginine-based gemini surfactant, C9(LA)2, against mixed biofilms of fluconazole-resistant Candida albicans and extended-spectrum beta-lactamase (ESBL)-producing E. coli, and the preventive effect of this surfactant impregnated in CVCs on the formation of inter-kingdom biofilms” Pérez et al (2025).

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Vascular access team review

“Nurse-driven central line insertion (NDCLI) programs offer a proactive approach to address these challenges by empowering trained vascular access nurses to perform CVC and AC insertions” Girgenti et al (2025).

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Impact of OPAT on hospital admission avoidance

“This review underscores the potential for OPAT to optimise hospital resources, improve patient outcomes and lower healthcare costs, advocating for its expansion across NHS trusts to address growing demands for sustainable and efficient healthcare delivery” Acuram et al (2025).

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Prehospital sepsis recognition and antibiotic administration

“For patients in whom a sepsis alert was initiated, EMS clinicians adhered to the sepsis protocol and administered antibiotics prior to hospital arrival in 97% of cases. Patients received their first antibiotic a median of approximately 26 minutes after 9-1-1 call and 11 minutes prior to hospital arrival” Antevy et al (2025).

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CLABSI in critical care – Full Text

“This study highlights the importance of minimizing CVC use and limiting the number of insertions to reduce CLABSI risk. Effective management strategies should focus on reducing CVC duration and frequency” Alomari et al (2025).

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Blood sampling pain in preterm infants – Full Text

“Based on the results of this study, the use of combined non-pharmacological interventions of NSS has been more effective in reducing the pain caused by venous blood sampling than other conditions where two or one non-pharmacological intervention were used” Yadollahzadeh et al (2025).

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Complications of micropuncture vascular access in the ICU

“Micropuncture vascular access is increasingly being used in the intensive care unit (ICU) due to its perceived reduction of bleeding complications in common ICU procedures. The authors report two rare complications associated with micropuncture kit use associated with vascular access” Okamoto et al (2025).

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Overview of peripheral vasopressor usage

“Peripheral vasopressors were commonly and safely used in our 10-hospital health system, particularly in the community hospitals. Peripheral initiation of vasopressors was not associated with increased mortality at 90 days, but was associated with decreased hospital length of stay” Shyu et al (2025).

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