Antimicrobial dosing recommendations for obese patients
“This is a comprehensive review of the dosing of different types of antimicrobials (antibiotics, antifungals, antivirals, and antituberculosis drugs) in obese patients, where the literature on PK and possible dosing strategies in obese adults was critically assessed” Castro-Balado et al (2024).
Early blood administration by Emergency Medical Services – Full Text
“Prehospital blood programs must be thoughtfully planned, have multiple safeguards, ensure adequate training and credentialing processes, and be responsible stewards of blood resources” Levy et al (2024).
Neonatal central venous catheterization protocol
“Recently, the GAVeCeLT has proposed a protocol called SICA-PED (i.e. Safe Insertion of Central Access in Pediatric patients) and includes seven evidence-based strategies” Spagnuolo et al (2024).
Oncology infusion center daily nurse staffing ratio
“This study assessed three acuity models across multiple centers to determine whether acuity was superior to patient volumes or patient hours in predicting the number of nurses needed to care for scheduled patients in an OIC, as well as the effect on objective metrics of missed nurse lunch breaks and patient wait times” Tobias et al (2024).
Evolution of intravenous medication errors
“This narrative review demonstrates a growing interest in systems-based risk management for intravenous drug therapy and in introducing new technology, particularly smart infusion pumps and preparation systems, as systemic defenses” Kuitunen et al (2024).
Hospital-acquired bloodstream infections in cancer patients
“We summarise strengths and weaknesses of commonly used surveillance definitions and denominators in the setting of cancer care; existing surveillance practice; epidemiology of haBSI and CLABSI; prevention strategies; and current knowledge gaps” MacPhail et al (2024).
Impact of CVC removal on neonatal CLABSI – Full Text
“Staphylococcus capitis is an increasingly prevalent pathogen in the neonatal setting, frequently causing central-line-associated bloodstream infections (CLABSIs) that can be difficult to eradicate. Central venous catheter (CVC) removal versus in situ treatment with CoNS CLABSIs is a controversial treatment strategy with no clear consensus” Sala et al (2024).
Fillable elastomeric pump technology
“Due to advances in elastomeric pump technology, there are now devices available that can be filled with intravenous (IV) therapy at the bed or chair side. These devices are safe, reliable and enable the patient to be mobile when having their infusion” Barton et al (2023).
Parenteral nutrition as a vehicle for drug delivery
“This review focuses on the utilization of Total Parenteral Nutrition (TPN) as a method for delivering drugs. It discusses the benefits and difficulties associated with its commercial application and offers suggestions for future research endeavors” Bakrey et al (2024).
What is the effect of taurolidine on the time-to-positivity of blood cultures – Full Text
“In the presence of taurolidine, the TTP was considerably delayed or vials even remained negative as compared to vials containing heparin, citrate or NaCl. This effect was dose-dependent. The delayed TTP was much less pronounced in the presence of blood, but still notable” van den Bosch et al (2024).
Wrong-route drug administration errors – Full Text
“Oral drug formulations and enteral feeds may inadvertently be administered intravenously. Intravenous medications may be inadvertently administered intra-arterially. These examples of wrong-route drug administration errors have the potential to cause significant organ dysfunction and even death” Taylor and Blockman (2023).
PICC related CLABSI in neonates – Full Text
“Low birth weight, premature delivery, off-site nutrition, long catheterization time, and 5-minute APGAR score ≤7 are independent risk factors for catheter-related bloodstream infection in neonates with peripherally inserted central venous catheters. The pathogenic bacteria are fungi and multidrug-resistant bacteria” Zhang et al (2024).
Home parenteral nutrition best practice examples – Full Text
“This article is based on presentations and discussions held at the International Safety and Quality of PN Summit, providing insights into aspects of home PN (HPN) and examples of good HPN practice” Kumpf et al (2024).
Intravenous protection device to prevent self-injection – Full Text
“The misuse of medical IV access is a potential source of prolonged hospitalizations and fatal overdoses nationwide. On two separate occasions, patients were found dead in our ED bathroom after overdosing by accessing their IV site for self-injection. These events prompted the development of the IV SafeLock prototype” Bragg et al (2024).
Needlestick injuries in medical school – Full Text
“The aim was to determine numbers and causes of NSIs as well as the frequency with which medical students report NSIs in the final stages of study” Keicher et al (2024).
Microplastics from neonatal parenteral nutrition circuit – Full Text
“The leaching of particles from plastic health care equipment in the blood of intensive care patients has been associated with several health risks, and as such, similar health risks could occur with leaching of microplastics” Vercauteren et al (2024).
CIMUS consensus statement on POCUS competencies – Full Text
“The CIMUS group recommends 28 competencies be considered mandatory and 3 as optional for internal medicine physicians performing POCUS guided thoracentesis, paracentesis, and CVC placement” Canadian Internal Medicine Ultrasound (2024).
Catheter-related superior vena cava syndrome case study – Full Text
“Here we present a case of a patient on maintenance hemodialysis who developed catheter-related superior vena cava syndrome and subsequently suffered from hemorrhagic pericardial tamponade after undergoing percutaneous transluminal angioplasty and stenting” Zhao and Wang (2024).
Ultrasound guided implantation of venous access ports – Full Text
“The aim of this study was to present demographic information of patients undergoing totally implantable venous access port (TIVAP) implantation and to investigate the rates of early and late complications, assessing the benefits of performing the procedure under US guidance” İlhan et al (2024).
PICC insertion in patients with chronic kidney disease
“Peripherally Inserted Central Catheters play an increasingly important role in Central Venous Access Devices. However, the use of these devices should be carefully considered in specific situations such as central catheterisation in patients with chronic kidney disease” Ajello et al (2024).
Midline catheter insertion simulation-based learning method
“This study aimed to propose and assess a simulation-based learning method for the placement of MCs in novice practitioners” Slosse et al (2024).
Pediatric hemolyzed laboratory samples in ED – Full Text
“Hemolysis in the pediatric ED population is a frequent complication that occurs at similar rates as in adults. PIVCs placed in the hand/wrist were associated with higher odds of hemolysis compared to those placed in the antecubital fossa” Mielke et al (2024).
Peripheral intravenous catheter dwell time
“This review examines the differences in dwell times between traditional PIVCs and ultrasound-guided PIVCs (USGPIVCs) and their implications for patient care” Harrell (2024).
Health-related quality of life in OPAT patients
“OPAT is associated with improved patient-reported quality of life and facilitates early return to work or school. Nevertheless, it is crucial to closely monitor patients with a lower baseline quality of life to optimize their overall OPAT experience” Durojaiye and Kritsotakis (2024).
Reducing umbilical catheter migration – Full Text
“This study evaluates the effectiveness of a novel device, LifeBubble, in reducing umbilical cord catheter (UC) migration and associated complications in neonates” Perl et al (2024).
Risk of PICC complications in cancer patients
“To identify the trends in the prevalence of peripherally inserted central catheter (PICC) related complications in cancer patients and explore the risk factors for complications and occurrence speed” Nie et al (2024).
IV pumps and filters for stem cell infusion
“A nurse-driven quality improvement project sought to determine whether peristaltic pumps and filtered tubing compromised the safety of stem cell infusion” Miles and Hoffman (2024).
Environmental impact of blood transfusion
Environmental impact of blood transfusion Abstract: Background: Healthcare activities significantly contribute to greenhouse gas (GHG) emissions. Blood transfusions require complex, interlinked processes to collect, manufacture,
CVC placement with eye-tracking glasses
“In this observational study, the study authors describe their experience using first-person wearable video-recording technology to precisely measure the timing of discrete events during CVC placement by anesthesia residents and anesthesiologists” Vergara-Escudero et al (2024).
CLABSI rates compared with hospital-onset bloodstream infections – Full Text
“To evaluate the comparative epidemiology of hospital-onset bloodstream infection (HOBSI) and central line-associated bloodstream infection (CLABSI)” Krishnan et al (2024).
Peripheral arterial catheter securement
“Peripheral arterial catheters (PACs), and their associated complications, are common in the pediatric intensive care unit (PICU). Accidental catheter displacement and non-functional PACs are the most common complications, and this may be related to inadequate catheter securement” Pilarz et al (2024).
Joint Commission accreditation and CLABSI rates
“This study evaluated the relationship between Joint Commission accreditation and health care-associated infections (HAIs) in long-term care hospitals (LTCHs)” Schmaltz et al (2024).
Compartment syndrome due to intravenous infiltration – Full Text
“We report the cases of two children who developed compartment syndrome of the dorsum of the hand and forearm after receiving only glucose acetate Ringer’s solution during hospitalization, with one case requiring a releasing incision” Tomori et al (2024).
Blood culture bottle fill volume – Full Text
“Therefore, it is crucial to fill a blood culture bottle with enough blood to maximize the detection of bacteremia. Current CLSI guidelines for adult blood culture collection recommend 2 sets, that is, 4 bottles of blood cultures, each filled with 10 mL of blood to maximize detection of bacteremia” Keller et al (2024).
Stuck haemodialysis catheter case report – Full Text
“This case serves as a timely reminder of the risks of long-term tunnelled haemodialysis catheters and as a caution towards proceeding with kidney transplantation in those with long-term haemodialysis catheters in situ” Burnett et al (2024).
Tobramycin serum sample collection from PICC – Full Text
” Tobramycin serum samples collected by PICC appear to be similar in value to PV collections. Collecting aminoglycoside levels by PICC rather than PV may reduce patient discomfort and improve quality of life. Additional multicenter studies are needed to confirm these results” Sherwood et al (2024).
Infection prevention practice gaps – Full Text
“The top three IPC gaps were absence of drug diversion program (77%), lack of audits and feedback for insertion and maintenance of central venous catheters (76%), and missing laboratory risk assessments to identify tests that can be offered safely for patients under investigation for HRP/SCD (76%)” Soma et al (2024).
High flow PICC for apheresis
“High flow PICC is a viable alternative for apheresis to maintain an adequate flow of 5 ml/s and can be used as a single catheter throughout the HSCT process, reducing the risks from anesthesia and the catheter insertion procedure” Kremer et al (2024).
Economic burden of difficult intravenous access
“This is the first formal analysis estimating the significant economic burden of difficult venous access in emergency departments via peripheral intravenous catheter placement, a task frequently performed by nurses” Gala et al (2024).
Dalbavancin OPAT treatment – Full Text
“We present a case of a homeless patient with MRSA bacteremia and osteomyelitis successfully treated with dalbavancin. Our case highlights the potential of dalbavancin’s once-weekly dosing to improve adherence and treatment outcomes in challenging outpatient scenarios” Sabina et al (2024).
Vascular access device type for systemic anti-cancer therapy
“Our findings suggest a systematic review and meta-analysis of VAD use for intravenous SACT can be considered. However, the development of a core outcome set for SACT should be prioritised” Duggan et al (2024).
Turkish version of the Difficult Intravenous Access Scale
“The Turkish version of the scale is a valid and reliable scale for determining the risk of difficult intravenous access. The practical use of this scale by healthcare professionals will enable earlier diagnosis of patients with difficult vascular access” Taşkın and Günay İsmailoğlu (2024).
How clinicians adapt to new peripheral IV cannula – Full Text
“The study aims to explore clinicians’ experience with the insertion of a new guidewire peripheral intravenous catheter (PIVC) introduced in the emergency department (ED) setting” Xu et al (2024).
Infusion set replacement interval study protocol – Full Text
“Therefore, the objective of this trial is to compare the efficacy of 24-h and 96-h replacement intervals for infusion sets on CLABSI among critically ill adults who have central venous access devices” Xu et al (2024).
Umbilical vascular catheter adverse events – Full Text
“Adverse events related to insertion occurred in a relatively high percentage of umbilical catheters placed. Increased dwell time remains a significant risk factor for catheter migration and overall failure” Gibson et al (2024).
Central venous catheter-related thrombosis guidelines – Full Text
“The overall quality of the guidelines is high, but there are few preventive measures for central venous CRT involved in the guidelines. All preventive measures have yet to be systematically integrated and evaluated, and no risk assessment scale dedicated to this field has been recommended” Zhang et al (2024).
Vascular access type for melflufen administration – Full Text
“Melflufen PVC and CVC administrations are bioequivalent based on melphalan pharmacokinetic parameters. Melflufen via PVC was well tolerated, with no infusion-related reactions or new safety signals and may represent an alternative route of administration” Pour et al (2024).
AI-assisted CLABSI surveillance
“AI shows promise in enhancing HAI surveillance, potentially streamlining tasks, and freeing health care staff for patient-focused activities. Effective AI use requires user education and ongoing AI model refinement” Wiemken and Carrico (2024).
Virtual reality for procedural pain management
“VR as a non-pharmacological adjunct reduced some procedure-related pain and anxiety without increasing the procedural duration” Schaake et al (2024).
OPAT services in Germany – Full Text
“The study demonstrates that OPAT can be safely conducted in Germany. In preparation for its broader implementation, crucial next steps include creating medical guidelines, fostering interdisciplinary and inter-sectoral communication, as well as creating financial and structural regulations that facilitate and encourage the adoption of OPAT” Schmidt-Hellerau et al (2024).
CLABSI burden outside acute care hospitals
“Surveillance is required to understand the burden of CLABSI in the community to identify targets for CLABSI prevention initiatives outside acute care settings” Oladapo-Shittu et al (2024).
Nursing care of patients with peripherally inserted central catheter
“Patients in the observation group had reduced NPRS, SAS, SDS and PFS-R scores, total incidence of unplanned extubation of PICC and the total incidence of catheter-related complications, and a higher nursing satisfaction rate in comparison to those in the control group” Li et al (2024).