Frequency of OPAT linked adverse events – Full Text
“Almost 1 in 3 patients leaving on OPAT experienced an adverse event. A 6 Sigma analysis identified heterogeneity in our process and incorrect assumptions among stakeholders. Next steps should focus on improving ID documentation and ensuring all patients leaving on OPAT have an ID clinic visit scheduled within 14 days after discharge” Keri et al (2025).
Preventing bloodstream infections associated with central venous access devices – Full Text
“A prioritization study with infection preventionists using the SHEA CLABSI prevention framework identified priorities for IVCare intervention testing as: vascular access teams, education/competency for CVAD insertion/post-insertion care, sutureless securement, connector type and decontamination method” Rickard et al (2025).
PICC excellence in cancer care – Full Text
“This editorial examines the current landscape of PICC utilization in cancer care, highlighting the critical intersection between evidence-based practice and patient-centered outcomes” Mussa and Defrancisco (2025).
Unusual catheter course was persistent left superior vena cava – Full Text
“Contrast-enhanced computed tomography demonstrated the absence of the left brachiocephalic vein, with the left internal jugular vein joining the left subclavian vein and descending directly to the heart, confirming persistent left superior vena cava (PLSVC)”
Study supports IV flush and discard ahead of blood sampling from VAD – Full Text
“In conclusion, our results support flush and discard ahead of haemostatic assay blood sampling in newly inserted catheters. Furthermore, the results enhance the understanding of central venous catheter-related thrombosis formation” Naddi et al (2025).
How to manage an intravenous fluid shortage crisis – Full Text
“Hurricane Helene’s disruption of Baxter’s North Carolina manufacturing facility in September 2024 created significant supply disruptions and an urgent need to reduce intravenous fluid (IVF) usage across our 12 acute care hospital health system” Nahass et al (2025).
Rivaroxaban prophylaxis for PICC-related thrombosis – Full Text
“Two months of rivaroxaban prophylaxis effectively and safely reduce CRT incidence in breast cancer patients with PICC” Sang et al (2025).
Internal jugular vein thrombosis – Full Text
“IJVT presents with distinct biomarker profiles when associated with CVADs, characterized by lower systemic fibrinolysis and heightened inflammation. Recognition of these differences may refine diagnostic thresholds and guide prophylactic strategies. Larger prospective studies are warranted” Boccatonda et al (2025).
Azygos vein as an alternative route for haemodialysis catheterisation – Full Text
“This case demonstrates the azygos vein as a viable alternative for haemodialysis access in SVC stenosis” Pushevski et al (2025).
Comparison of chemo-port insertion performed by radiologists or surgeons – Full Text
“Chemo-port insertion is performed by a radiologist or surgeon in an interventional radiology (IR) suite or an operating room (OR). The complication rate is approximately 3%-4%. However, there is still a lack of data for comparison when it is performed in different conditions such as IR suite and OR” Park et al (2025).
Are routine X-rays necessary after central venous catheter removal – Full Text
“Despite the lack of evidence supporting their necessity, routine post-removal chest X-rays for central venous catheters (CVCs) are still performed in some hospitals due to persistent misconceptions about their benefits” Breitwieser et al (2025).
Pediatric blood culture contamination rates
“Younger patient age and ED nurse blood cultures had greater odds of contamination. Results can inform focused training on quality collection and testing techniques, as well as the creation of enhanced staffing models to increase phlebotomist collections” Childress et al (2025).
Simulation training for intravenous catheter placement
“This study seeks to describe the impact of a single preclinical IVC session on skill retention in students entering the transition to clerkship” Gibson et al (2025).
Using vein finder technology for venipuncture – Full Text
“The use of vein finder technology may significantly reduce pain, improve behavioural states and enhance procedural success in preterm infants compared with traditional venipuncture methods. These findings suggest that incorporating this technology into NICUs practice might benefit patient comfort and clinical efficiency” Sayed et al (2025).
Catheter-associated bloodstream infection risk assessment
“Our study showed a significantly high incidence of CABSI and CRBSI in non-ICU adult patients. By identifying the risk factors of these infections, it suggests the settings in which stringent infection prevention strategies are needed” Borgonovo et al (2025).
Blood culture standard operating procedure compliance
“Our study highlights how educational interventions can influence quality of BC. Continuous monitoring and interventions are key for quality improvement in BC processes” Fernandes et al (2025).
Hyaluronidase-facilitated subcutaneous immunoglobulin administration – Full Text
“This review describes the key role of nursing professionals in facilitating successful transition from IVIG to subcutaneous therapy in patients with CIDP and draws on experience from ADVANCE-CIDP 1 to help equip nursing staff with the knowledge and confidence to support patients with CIDP initiating fSCIG 10% as a maintenance treatment” Duff et al (2025).
Management resources for healthcare-associated infection prevention – Full Text
“We previously reported results of an in-depth study of management practices to prevent healthcare-associated infections. Here we describe the development of an online toolkit containing resources that can be used to implement six of these key management practices” Rush et al (2025).
Type of catheter lock solution for patients on therapeutic heparin – Full Text
“Citrate or saline HD catheter lock may be preferable to heparin HD catheter lock in patients on intravenous heparin infusions, especially in high-bleed-risk surgical patients” Tuggle et al (2025).
C diff infection rate associated with OPAT patients – Full Text
“Herein, we describe characteristics of OPAT patients with CDI at a large academic medical center. Despite prolonged antibiotic exposure, the incidence rate of CDI was low” Vo et al (2025).
Peripheral intravenous catheter management – Full Text
“This article reviews the evidence for the appropriate use of short PIVCs in hospitalized patients, assesses the ongoing need for PIVCs, provides recommendations for alternative options, and argues for promptly removing a PIVC that is no longer in use” Ray-Barruel and Alexander (2025).
Revised procedural checklists for invasive procedures – Full Text
“We have focused on procedures which are commonly performed in Critical Care Units (intubation, bronchoscopy, intercostal drain insertion, tracheostomy insertion, central venous catheter insertion). The checklists have been designed to enable departments to use and adapt to make them unit specific” Windsor et al (2025).
Vascular Access and IV Therapy Resource

Hyaluronidase-facilitated subcutaneous immunoglobulin administration – Full Text
“This review describes the key role of nursing professionals in facilitating successful transition from IVIG to subcutaneous therapy in patients with CIDP and draws on experience from ADVANCE-CIDP 1 to help equip nursing staff with the knowledge and confidence to support patients with CIDP initiating fSCIG 10% as a maintenance treatment” Duff et al (2025).
Management resources for healthcare-associated infection prevention – Full Text
“We previously reported results of an in-depth study of management practices to prevent healthcare-associated infections. Here we describe the development of an online toolkit containing resources that can be used to implement six of these key management practices” Rush et al (2025).
Type of catheter lock solution for patients on therapeutic heparin – Full Text
“Citrate or saline HD catheter lock may be preferable to heparin HD catheter lock in patients on intravenous heparin infusions, especially in high-bleed-risk surgical patients” Tuggle et al (2025).
C diff infection rate associated with OPAT patients – Full Text
“Herein, we describe characteristics of OPAT patients with CDI at a large academic medical center. Despite prolonged antibiotic exposure, the incidence rate of CDI was low” Vo et al (2025).
Peripheral intravenous catheter management – Full Text
“This article reviews the evidence for the appropriate use of short PIVCs in hospitalized patients, assesses the ongoing need for PIVCs, provides recommendations for alternative options, and argues for promptly removing a PIVC that is no longer in use” Ray-Barruel and Alexander (2025).
Revised procedural checklists for invasive procedures – Full Text
“We have focused on procedures which are commonly performed in Critical Care Units (intubation, bronchoscopy, intercostal drain insertion, tracheostomy insertion, central venous catheter insertion). The checklists have been designed to enable departments to use and adapt to make them unit specific” Windsor et al (2025).
Inadvertent arterial puncture during CVC insertion – Full Text
“Our review offers a simple management algorithm for the mechanical complications of CVC insertion. This algorithm focuses on inadvertent arterial puncture/cannulation, with steps ranging from external compression to endovascular repair or surgical intervention” Woodfall and van Zundert (2025).
Intravenous drug incompatibilities in neonatal intensive care units – Full Text
“Multi-lumen infusion devices limit but do not prevent the occurrence of PCIs, particularly in the event of a preparation error. Despite the use of this type of device, great vigilance is still required, particularly with regard to prescription analysis and reconstitution procedures” Salomez-Ihl et al (2025).
Patient satisfaction with vascular access – Full Text
“This multi-center study aimed to investigate the correlation between vascular access satisfaction (VAS) and demoralization syndrome (DS) in elderly patients undergoing maintenance hemodialysis (MHD)” Lv et al (2025).
Molecular characteristics of CVC biofilm formation – Full Text
“Very high prevalence of genes associated with biofilm formation was observed in clinical isolates of Staphylococcus spp. and K. pneumoniae. High-level resistance to all antimicrobials was observed in K. pneumoniae strains” Vodianyk et al (2025).
Psychological impact of vascular access devices – Full Text
“VADs for parenteral nutrition are associated with significant psychological burden in young patients. These findings highlight the need for routine psychological screening and targeted interventions to support this population” Baudolino et al (2025).
OPAT outcomes survey – Full Text
“We surveyed outpatient parenteral antimicrobial therapy team members to assess the importance of specific program metrics while eliciting collection barriers, which can guide establishing or restructuring programs” Makadia et al (2025).
PICC associated median nerve hematoma – Full Text
“This case report demonstrates the utility of ultrasound (US) in the diagnosis, characterization, and follow-up of an intraneural median nerve hematoma following peripherally inserted central catheter (PICC) placement” Nixon et al (2025).
Effectiveness of vascular catheter removal following CLABSI diagnosis – Full Text
“A Candida spp. isolation was found to be significantly associated with a higher likelihood of catheter removal (p = 0.04). Our findings suggest that, in non-ICU CRBSI and CABSI cases, VAD removal may be associated with improved outcomes when feasible” De Capitani et al (2025).
Prehospital antibiotics and intravenous fluids for patients with sepsis – Full Text
“Prompt recognition and treatment of patients with sepsis improve survival. Patients transported to hospital with sepsis often do not receive treatment until they are assessed in emergency departments. Initiation of treatments by paramedics at the point of first contact may improve outcomes for these patients” Scales et al (2025).
Persistent left superior vena cava identified during CVC insertion
“CT angiography confirmed PLSVC of Schummer’s Type 2, characterized by the absence of the right superior vena cava and left SVC draining into the right atrium via a dilated coronary sinus” Sinha et al (2025).
Predicting central venous catheter-related thrombosis in children
“This nomogram enables healthcare providers to estimate the risk of CRT in children with congenital heart disease, offering an effective tool for risk stratification and a basis for implementing targeted interventions” Jiang et al (2025).
Hemothorax following subclavian central venous catheter removal – Full Text
“This case highlights the potential for complications to arise not only during central venous catheter insertion but also during removal. Clinicians should ensure proper catheter positioning during insertion and implement post-removal monitoring protocols to detect rare but potentially life-threatening complications such as hemothorax” Kebede et al (2025).
Improving time to antibiotic administration in pediatric patients
“Timely administration of antibiotics in pediatric oncology patients undergoing chemotherapy is critical, particularly for those presenting with fever and a central line, due to their increased risk of severe infections” Cotton (2025).
IV versus IO vascular access
“Establishing vascular access early in out-of-hospital cardiac arrest (OHCA) is a crucial factor for improving prognosis. Clinical guidelines recommend both intravascular (IV) and intraosseous (IO) access, but the superiority of one technique over the other has yet to be determined” Hameed et al (2025).
CLABSI treatment with antibiotic lock therapy versus catheter removal
“Although ALT offers a non-invasive catheter salvage strategy, its association with higher relapse rates, particularly in CoNS BSI, suggests catheter removal should remain the preferred approach when feasible” Ranganath et al (2025).
Management of Staphylococcus aureus CRBSI
“Prospective observational studies seem to support the possibility of preserving the infected line in case of early pathogen identification and CRBSI management with empirical large-spectrum antibiotics, followed by targeted treatment once the antibiogram is available” Mandolfo et al (2025).
Skin disinfection prior to central venous catheterization survey – Full Text
“The Neonatal Vascular Access Group (AVN GdS) of the Italian Society of Neonatology reiterates the use of 2% chlorhexidine in a 70% alcohol solution for skin disinfection before central catheter insertion, as recommended by recent guidelines. However, specific precautions must be taken to avoid complications” D’Andrea et al (2025).
Pediatric PICC navigation
“Compared to traditional ultrasound-guided methods, magnetic navigation offers superior efficiency in pediatric PICC placement, highlighting its promising potential for clinical application and broader implementation” Chen et al (2025).
Timing of neonatal CVC removal
“We conclude that discontinuing PN and removing CVC at lower enteral feed volumes increases the risk of late-onset sepsis. Although the time to regain birthweight was longer, no differences in anthropometry were noted at discharge. Further evidence is required from low- and middle-income countries” Anne et al (2025).
Detailed narrative review of vascular access devices – Full Text
“Venous access devices can be categorized based on the termination site of the tip of the catheter into central and peripheral access devices. Selecting the type of venous access device depends on various factors, including the condition of the patient, the anticipated duration of therapy, the use of vesicant or hyperosmolar therapies and the potential risk of complications” Abdulelah et al (2025).
Ultrasound enhances umbilical venous catheter placement – Full Text
“In conclusion, ultrasound could be the standard of care for umbilical catheter placement, ensuring accurate vessel assessment and real-time visualization. Despite our limited sample, our findings highlight its superior precision and safety, reducing complications and the need for radiography” Cossovel et al (2025).
Incidence of CRBSI in immunosuppressed patients – Full Text
“Our findings suggest that intense immunosuppression in the setting of SOT is not associated with an increased risk of CRBSI in patients with renal failure utilizing TDC especially when a consistent and standardized protocol for the access and care of these catheters is utilized” El Mouhayyar et al (2025).
Central venous catheter insertion with eye-tracking glasses – Full Text
“We aimed to evaluate the effect of projection mapping (PM) on the quality and safety of central venous catheter (CVC) insertion under real-time ultrasound guidance” Miyazaki et al (2025).
Central line placement in difficult venous access patients – Full Text
“Infrared vein visualization (IVV) is a known technique commonly used for superficial vein mapping and peripheral venous access. This technical report explores the combined use of IVV and USG for CVC placement” Patankar (2025).