Extract:
The aim of this work was therefore to study vancomycin stability in syringes and assess its use (pH, osmolality, number of particles) during a continuous 24-hour infusion with and without inline filters at four concentrations—25, 40, 60 and 80 mg/mL—reconstituted in two solvents (WFI and saline solution) and diluted in saline solution.
Reference:Masse, M., Genay, S., Martin Mena, A., Carta, N., Lannoy, D., Barthélémy, C., Décaudin, B. and Odou, P. (2020) Evaluation of the stability of vancomycin solutions at concentrations used in clinical services. European Journal of Hospital Pharmacy. 27(e1), p.e87-e92. doi: 10.1136/ejhpharm-2019-002076.