Abstract:
Few data are available on the efficacy of 0.5% aqueous sodium hypochlorite (SH) for skin disinfection before peripheral catheter insertion. A total of 239 patients were randomly assigned to either one application of SH alone or one application of SH preceded by one application of 70% ethanol (ET-SH). Catheter colonisation, defined as a catheter tip culture growing more than 1000 CFU of a micro-organism per mL, occurred in 29 patients (33% – 89 colonisations per 1000 catheter days) in the SH group and in 31 patients (33% – 126 colonisations per 1000 catheter days) in the ET-SH.
Reference:Drugeon B, Pichon M, Marjanovic N, Mousse S, Seguin S, Raynaud C, Rahoui A, Frasca D, Mimoz O, Guenezan J. Peripheral venous catheter colonisation after skin disinfection with 0.5% aqueous sodium hypochlorite, preceded or not by one application of 70% ethanol (DACLEAN): A single centre, randomised, open-label, pilot study. J Hosp Infect. 2021 Nov 22:S0195-6701(21)00410-2. doi: 10.1016/j.jhin.2021.11.012. Epub ahead of print. PMID: 34822950.