Search

Risk factors for early IV port infections in adult oncologic patients

"Hematologic malignancy, hypoalbuminemia, leukopenia, and diabetes mellitus at the time of port placement were independent risk factors for early port infections" Skummer et al (2020).

"Hematologic malignancy, hypoalbuminemia, leukopenia, and diabetes mellitus at the time of port placement were independent risk factors for early port infections" Skummer et al (2020).

ReTweet

Abstract:

Purpose: The purpose of this study was to retrospectively investigate risk factors for chest port (port) infections within 30 days of placement (early port infections) in adult oncologic patients.

Materials and methods: This single-institution, three-center retrospective study identified 1,714 patients (868 males, 846 females; median age 60.0 years old) who underwent port placement between January 2013 and August 2017. All patients received an intravenous antibiotic prior to port placement. The median absolute neutrophil count was 5,260 cells/μL, the median white blood cell (WBC) count was 7,700 cells/μL, and the median serum albumin was 4.00 g/dL at the time of port placement. Double-lumen ports were most commonly implanted (74.85%) more frequently in an outpatient setting (72.69%). Risk factors for early port infections were elucidated using univariate and multivariate proportional subdistribution hazard regression analyses.

Results: A total of 20 patients (1.2%) had early port infections; 15 patients (0.9%) had positive blood cultures. The mean time to infection was 20 days (range, 9-30 days). The port-related 30-day mortality rate was 0.2% (4 of 1,714 patients). Most bloodstream infections were attributed to Staphylococcus spp. (n = 11). In multivariate analysis, hematologic malignancy (hazard ratio [HR], 2.61; 95% confidence interval (CI), 1.15-5.92.; P = .02), hypoalbuminemia (albumin <3.5 g/dL; HR, 3.52; 95% CI: 1.48-8.36; P = .004), leukopenia (WBC <3,500 cells/μL; HR, 3.00; 95% CI: 1.11-8.09; P = .03), and diabetes mellitus (HR, 3.71; 95% CI: 1.57-8.83) remained statistically significant risk factors for early port infection.

Conclusions: Hematologic malignancy, hypoalbuminemia, leukopenia, and diabetes mellitus at the time of port placement were independent risk factors for early port infections.

Reference:

Skummer P, Kobayashi K, DeRaddo JS, et al. Risk Factors for Early Port Infections in Adult Oncologic Patients [published online ahead of print, 2020 Aug 10]. J Vasc Interv Radiol. 2020;S1051-0443(20)30466-8. doi:10.1016/j.jvir.2020.05.018

Facebook Twitter Linkedin Rss Envelope

About IVTEAM citation library

IVTEAM has established itself as a core global resource for infusion and vascular access practitioners. Each day 6K users have access thousands of pages of easy to access relevant intravenous news and updates. IVTEAM offers its visitors a premier service that has no financial or subscriber based restrictions. The editorial stance of IVTEAM is to ensure no editorial restrictions exist; content remains unbiased and independent.

It is crucial that IVTEAM stays up-to-date and offers visitors regular, current updates. Each day news feeds are analysed, websites searched and various additional sources of information visited. This results in large amounts of data being sifted through for relevant information every day. Only a small amount of data is relevant to IV practice and makes it onto IVTEAM.

Read more
Copyright 2025 © IVTEAM. All rights Reserved.

Register for free citation alerts

Supporting your vascular access and infusion therapy learning journey