Objective: To verify the effectiveness of AccuVeinAV300® in the success of peripheral intravenous catheterization in adults with difficult intravenous access, compared to the traditional clinical method.

Method: This is a description of the protocol for a randomized controlled clinical trial in a parallel, non-blinded group. It will be carried out with patients from the medical and surgical clinics of a university hospital. The sample will be determined after a pilot study with 60 patients. Inclusion criteria will be age 18 or above, difficult intravenous access and no clinical deterioration. Participants in the intervention group will undergo peripheral intravenous catheterization with the AccuVeinAV300®, which is a vein viewer with a near-infrared light emitter. For patients in the control group, the procedure will take place using the traditional clinical method, using inspection and palpation. The procedure will be considered successful when the catheter is inserted on the first attempt with blood reflux, as long as it is possible to infuse 10 ml of saline solution without complications. Data collected will include observation of peripheral intravenous catheterization, information collected from the patient, and from medical records. Data analysis will be descriptive, univariate and multiple.

Bittencourt IS, Santos LMD, Kusahara DM, Avelar AFM. AccuVein® versus traditional clinical methods in successful intravenous catheterization in adults: a randomized trial protocol. Rev Gaucha Enferm. 2025 May 12;46:e20240146. English, Portuguese. doi: 10.1590/1983-1447.2025.20240146.en. PMID: 40366964.