Complications and tolerability of PICC in neuro-oncological patients

As a primary objective, this study aimed to collect complications related to PICCs in primary neuro-oncological patients. As a secondary objective, the study aimed to evaluate PICC tolerability” Simonetti et al 92019). Abstract: PURPOSE: The use of central venous catheters with peripheral insertion (PICC) has increased rapidly in recent years, particularly in cancer patients. The […]
Alarm burden associated with smart infusion pumps

Smart pumps have the ability to improve neonatal medication safety when compliance with dose error reducing software is high” Melton et al (2019). Abstract: BACKGROUND: Smart pumps have been widely adopted but there is limited evidence to understand and support their use in pediatric populations. Our objective was to assess whether smart pumps are effective […]
CLABSI due to coagulase-negative staphylococci

Little research has been carried out on recurrences of catheter-related bloodstream infection due to coagulase-negative staphylococci (CoNS-CRBSI)” Hebeisen et al (2019). Abstract: Little research has been carried out on recurrences of catheter-related bloodstream infection due to coagulase-negative staphylococci (CoNS-CRBSI). The main objective of this study was to characterize patients with CoNS-CRBSI and infection recurrence after […]
Ultrasound guided central line insertion in neonates

The aim is to compare pain scores between ultrasound-guided central line insertion and peripherally inserted catheter in neonates in a prospective randomized single center study” Sabouneh et al (2019). Abstract: BACKGROUND: Central lines can be placed through different techniques, either peripherally or centrally. Although they have the same aim, decision to use one of these […]
Progress in pathogen diagnostics in BSI

During the past two decades major improvements has been made in the diagnostic performance of blood culture diagnostics through actions on pre-analysis and time-to-result” Lamy et al (2019). Abstract: Background: Bloodstream infection (BSI) is a major public health burden worldwide, with high mortality. Patient outcome is critically influenced by delayed therapy, and fast and accurate […]
Incidence of phlebitis following the use of peripheral IV catheters

This study aims to investigate the incidence of phlebitis and to evaluate factors contributing to the development of phlebitis” Mandal and Raghu (2019). Abstract: CONTEXT: Peripheral vein cannulation is commonly performed for rapid and accurate administration of medications. Phlebitis is one of the commonest complications that develop after intravenous catheter application. AIMS: This study aims […]
Central venous access and increased risk for thromboembolism

To investigate if patients receiving neoadjuvant chemotherapy (NAC) for muscle-invasive bladder cancer (MIBC) had an increased risk of thromboembolic events (TEE) and to evaluate when these events occur on a timeline starting from 6 months pre-cystectomy, during NAC-administration and 60 months post-cystectomy” Ottosson et al (2019). Abstract: PURPOSE: To investigate if patients receiving neoadjuvant chemotherapy […]
Blood culture results before and after antimicrobial administration

Administering antimicrobial agents before obtaining blood cultures could potentially decrease time to treatment and improve outcomes, but it is unclear how this strategy affects diagnostic sensitivity” Cheng et al (2019). Abstract: Background: Administering antimicrobial agents before obtaining blood cultures could potentially decrease time to treatment and improve outcomes, but it is unclear how this strategy […]
Extravasated Peripherally Inserted Central Catheter

Intraoperatively, an un-anticipated diagnosis of extravasated peripherally inserted central venous cannula (PICC) was made. Total parenteral nutrition had extravasated into the mediastinum and thorax” Licina (2019). Abstract: A 48-year-old woman was scheduled for flexible bronchoscopy, video-assisted thoracoscopic surgery and mediastinal washout. She had developed voice changes, difficulty swallowing, shortness of breath with a fever and […]
Dosage regimens for meropenem in children with pseudomonas infections

There have been literature reports that some recommended meropenem dosage regimens may fail to meet therapeutic targets in some high-risk children and adults” Hassan et al (2019). Abstract: There have been literature reports that some recommended meropenem dosage regimens may fail to meet therapeutic targets in some high-risk children and adults. We evaluated this observation […]
Security framework for networked infusion pumps

To cover these gaps, this research proposes Integrated Safety, Security, and Privacy (ISSP) Risk Assessment Framework to determine the risk level of the device and required security controls. It is, then applied to a case scenario of an infusion pump and further evaluated by comparing it with current standards and practices” Yasqoob et al (2019). […]
PICC insertion and changes of thrombomodulin and plasma protein C

This study aimed to evaluate the changes and clinical significance of thrombomodulin (TM) and plasma protein C (PC) in patients with cancer before and after peripherally inserted central catheter placement (PICC)” Yan et al (2019). Abstract: OBJECTIVE: This study aimed to evaluate the changes and clinical significance of thrombomodulin (TM) and plasma protein C (PC) […]
Evaluation of incompatible intravenous infusion administration

We aimed to evaluate and quantify incompatible coadministrations of continuous intravenous medication in the daily clinical practice of a PICU/NICU” Häni et al (2019). Abstract: OBJECTIVES: We aimed to evaluate and quantify incompatible coadministrations of continuous intravenous medication in the daily clinical practice of a PICU/NICU. METHODS: We conducted a retrospective, observational study in the […]
Survey of propofol infusions in PICUs in North America

The objective of this survey was to assess the current use of continuous infusion propofol in PICUs across the United States and Canada” Kurek et al (2019). Abstract: OBJECTIVE: The objective of this survey was to assess the current use of continuous infusion propofol in PICUs across the United States and Canada. METHODS: A list […]
CLABSI in children on home parenteral nutrition

Reliable venous access is prerequisite for patients receiving long-term parenteral nutrition (PN)” Trivić et al (2019). Abstract: Reliable venous access is prerequisite for patients receiving long-term parenteral nutrition (PN). However, central venous catheters (CVCs) are an important risk factor for the development of potentially lethal complications, including catheter related bloodstream infection (CRBSI). We have retrospectively […]
CLABSI and central venous catheter management

Despite pathogen-specific guideline recommendations for CVC removal, compliance with national guidelines was poor. CVC salvage was attempted in the majority of CLABSI episodes in our cohort and resulted in a significantly higher treatment failure rate” Hecht et al (2019). Abstract: BACKGROUND: National guidelines recommend removal of central venous catheters (CVCs) for central line-associated bloodstream infections […]
PICC in haematopoietic stem cell transplantation

To analyze the incidence of complications related to the central peripheral insertion catheter and the viability of the infusion of haematopoietic stem cells through volumetric perfusion pumps” Santacatalina-Roig et al (2019). Abstract: AIMS: To analyze the incidence of complications related to the central peripheral insertion catheter and the viability of the infusion of haematopoietic stem […]
History of blood culture technique

In the clinical microbiology laboratory blood cultures are a vital technology for isolating bacteria and fungi” Allerberger et al (2019). Abstract: In the clinical microbiology laboratory blood cultures are a vital technology for isolating bacteria and fungi. They are the reference standard for diagnosing bloodstream infection and are considered a prerequisite for targeted antibiotic treatment […]
Use of intraosseous needles in neonates

IO access should be available on neonatal units and considered for early use in neonates where other access routes have failed” Scrivens et al(2019). Abstract: BACKGROUND: The use of intraosseous (IO) access during resuscitation is widely accepted and promoted in paediatric medicine but features less prominently in neonatal training. Whilst umbilical venous catheterization (UVC) is […]
Unexpected complication of arteriovenous fistula

Incidence of inadvertent arterial puncture secondary to central venous catheter insertion is not common with an arterial puncture rate of
Central line associated blood stream infections in gastroschisis patients

The aim of this study was to determine the risk of central line associated blood-stream infections (CLABSI) in neonatal gastroschisis patients, risk factors, outcomes, and financial implications” Snyder and Burjonrappa (2019). Abstract: PURPOSE: The aim of this study was to determine the risk of central line associated blood-stream infections (CLABSI) in neonatal gastroschisis patients, risk […]
Compartment syndrome of the leg following IO needle Insertion

Intraosseous (IO) needles are used in patients who are critically ill when it is not possible to obtain venous access” Kibrik et al (2019). Abstract: Intraosseous (IO) needles are used in patients who are critically ill when it is not possible to obtain venous access. While IO allows for immediate access, IO infusions are associated […]
Inadvertent arterial placement of central venous catheter

During such an emergency and placing without imaging guidance, sometimes inadvertent placement of CVC in subclavian artery (SCA) can occur” Shaw et al (2019). Abstract: The frequency of placing a central venous catheter (CVC) has increased and it is often performed in emergency situation for venous access. During such an emergency and placing without imaging […]
Safety of peripheral administration of vasopressor medications

Reports of the administration of vasopressors via PiVCs, when given for a limited duration, under close observation, suggest that extravasation is uncommon and is unlikely to lead to major complications” Tian et al (2019). Abstract: OBJECTIVE: Vasopressor medications have traditionally been administered via central venous catheters (CVCs), primarily due to concerns of peripheral extravasation of […]
Novel treatment of a vaccinia virus infection from an occupational needlestick

CDC was notified about an unvaccinated laboratory worker with a needlestick exposure to VACV, who developed a lesion on her left index finger” Whitehouse et al (2019). Abstract: Vaccinia virus (VACV) is an orthopoxvirus used in smallpox vaccines, as a vector for novel cancer treatments, and for experimental vaccine research (1). The Advisory Committee on […]
PICC-PORT totally implantable vascular access device in breast cancer patients

The peripherally inserted central catheter-PORT is a safe vascular device for chemotherapy delivery that achieves similar clinical results as traditional long-term vascular access devices (peripherally inserted central catheter and arm totally implantable vascular access device” Bertoglio et al (2019). Abstract: BACKGROUND AND OBJECTIVES: The increasing use of arm totally implantable vascular access devices for breast […]
Complication of right internal jugular vein catheter insertion

Iatrogenic superior vena cava pericardial fistula caused by central venous catheterization is rare but can lead to life-threatening condition” Bosemani and Sakthivel (2019). Abstract: Iatrogenic superior vena cava pericardial fistula caused by central venous catheterization is rare but can lead to life-threatening condition. Despite the potential risk of pericardial effusion causing pericardial tamponade, a conservative […]
Asymptomatic pulmonary artery embolization port catheter fragment

Broken catheter embolism is a rare but often fatal complication of implantable venous access devices” Tandon et al (2019). Abstract: Broken catheter embolism is a rare but often fatal complication of implantable venous access devices. Prompt removal is key to avoiding an adverse outcome. You may also be interested in… [rp4wp] Reference: Tandon, S., Livingston, […]
Outcome of underfilling of vacuum blood collection tubes

Underfilling of tubes leads to a higher proportion of blood aspirated with high velocity and relevant elevations in LD. This finding should be considered in cases of clinically implausible elevated LD activities” Neuwinger et al (2019). Abstract: Background: Lactate dehydrogenase (LD) activity is routinely monitored for therapeutic risk stratification of malignant diseases, but is also […]
Complications of indwelling port-catheter system for hepatic infusion

We discuss various cases with complications arising in the indwelling port area in hepatic arterial infusion of chemotherapy and report whether the system was salvaged” Ueda et al (2019). Abstract: INTRODUCTION: Regional hepatic arterial infusion of chemotherapy is performed for unresectable liver tumors via percutaneously implanted port-catheter systems; while these port-catheter systems are effective administration […]