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Intravenous push administration for OPAT – Full Text

"This narrative review summarizes the available data and practical implications of IVP administration of antimicrobials in the OPAT setting" Johnson et al (2023).

"This narrative review summarizes the available data and practical implications of IVP administration of antimicrobials in the OPAT setting" Johnson et al (2023).

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Intravenous push administration for OPAT

Abstract:

Intravenous push (IVP) antimicrobial administration refers to rapid bolus infusion of medication. This drug delivery method offers improved patient convenience, superior patient and nursing satisfaction, and cost savings when used in outpatient parenteral antimicrobial therapy (OPAT). Antimicrobial agents must demonstrate optimal physiochemical and pharmacologic characteristics, as well as sufficient syringe stability, to be administered in this manner. Additionally, impacts on medication tolerability, patient safety, and effectiveness must be considered. This narrative review summarizes the available data and practical implications of IVP administration of antimicrobials in the OPAT setting.

Reference:

Johnson TM, Whitman Webster LC, Mehta M, Johnson JE, Cortés-Penfield N, Rivera CG. Pushing the agenda for intravenous push administration in outpatient parenteral antimicrobial therapy. Ther Adv Infect Dis. 2023 Aug 15;10:20499361231193920. doi: 10.1177/20499361231193920. PMID: 37600976; PMCID: PMC10434178.

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