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Elastomeric pump continuous infusion case study – Full Text

"We describe a case of shoulder PJI due to WT carbapenem-susceptible PA and CRAB that was successfully treated using a two-step surgical procedure and antibiotic therapy with ciprofloxacin by mouth (PO), minocycline PO, and fosfomycin administered by an elastomeric pump as OPAT" Pallotto et al (2025).

"We describe a case of shoulder PJI due to WT carbapenem-susceptible PA and CRAB that was successfully treated using a two-step surgical procedure and antibiotic therapy with ciprofloxacin by mouth (PO), minocycline PO, and fosfomycin administered by an elastomeric pump as OPAT" Pallotto et al (2025).

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Elastomeric pump continuous infusion case study

Extract:

“In combination with other antibiotics (e.g. cefiderocol) fosfomycin has been used in the treatment of CRAB infections, and increasing evidence is available about its use as outpatient parenteral antibiotic treatment (OPAT). We describe a case of shoulder PJI due to WT carbapenem-susceptible PA and CRAB that was successfully treated using a two-step surgical procedure and antibiotic therapy with ciprofloxacin by mouth (PO), minocycline PO, and fosfomycin administered by an elastomeric pump as OPAT.”

Reference:

Pallotto C, Benvenuto MC, Francisci D. Shoulder prosthetic joint infection due to Pseudomonas aeruginosa and carbapenem-resistant Acinetobacter baumannii treated with ciprofloxacin, minocycline and continuous infusion fosfomycin as OPAT regimen: a case report. JAC Antimicrob Resist. 2025 May 21;7(3):dlaf087. doi: 10.1093/jacamr/dlaf087. PMID: 40400766; PMCID: PMC12093307.

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