Objective: The aim of this study was to assess the safety and clinical applications of TIVPA.

Methods: A retrospective analysis was conducted by reviewing the clinical data of 40 patients who underwent ultrasound-guided implantation of a TIVAP by a single-centre retrospective study (the Seventh People’s Hospital of Chongqing) between September and December 2018. Among the 40 patients, 15 patients underwent implantation of a TIVAP via the left axillary and 25 patients uderwent right axillary vein. Fifty patients who underwent puncture of the right internal jugular vein and indwelling of a TIVAP during the same period were recruited as controls. The success rate, percentage of patients who required ≤ 2 punctures, surgical time, and incidence of intra- and post-operative complications were compared between the two groups. A Fisher’s exact test was used to compare ratios and a t-test was used to compare the surgical time between the two groups.

Results: TIVAP was successfully implanted via the axillary or internal jugular vein under ultrasound guidance in all patients, and the success rate was 100% (40/40 and 50/50, respectively).. The experimental group’s surgery time is longer than that of the control group, However, the length of time is not statistically significant. [26±4 min vs. 22±3 min, P=0.000]. There were no significant differences in the percentage of patients requiring ≤ 2 punctures, the incidence of intra-operative pneumothoraces, and the incidence of mistaken punctures of arteries between the two groups [97.5% (39/40) vs. 96.0% (48/50), P=1.000; 0 (0/40) vs. 2.0% (1/50), P=1.000; 0 (0/40) vs. 4.0% (2/50), P=0.501]. Also, there were no appreciable variations in the frequency of long-term post-operative complications. (e.g., thrombosis and infection) between the two groups [2.5% (1/40) vs. 0 (0/50), P=0.444; 2.5% (1/40) vs. 2.0% (1/50), P=1.000].

Conclusion: Transaxillary vein ultrasound-guided implantation of a TIVAP is a low-risk, high efficiency procedure with low rate of complication.

Tian K, Jiang J, Liu D, Zhou H, Zhou L, Deng K, Cao Z. The Advantages and Safety of Ultrasound-Guided Infusion Port Implantation via Axillary Vein. Ann Vasc Surg. 2025 May 19:S0890-5096(25)00338-3. doi: 10.1016/j.avsg.2025.05.004. Epub ahead of print. PMID: 40398810.