PICC securement with cyanoacrylate glue
Abstract:
Background: Treatment via a peripherally inserted central venous catheter is important for anticancer treatment, perioperative management, and nutritional management. In this study, we aimed to investigate the usefulness of cyanoacrylate glue (CG) in managing peripherally inserted central venous catheters in adults.
Methods: This retrospective cohort study enrolled 411 adults requiring a central venous catheter for treatment in the Chiba University Esophageal-Gastro-Intestinal Surgery department between January 2021 and October 2022. The preventive effect of CG in reducing adverse events, including infection, tip migration, and thrombus formation, was evaluated by reviewing electronic medical records, chest radiographs, and contrast-enhanced computed tomography scans.
Results: CG and other dressings were used in 158 (CG group) and 253 (control group) patients, respectively. The incidence of catheter infection based on the clinical course was lower in the CG group (3.2%) than in the control group (9.1%; p=0.03). However, cases of infection confirmed by blood or catheter culture did not differ between the CG (1.3%) and control (1.9%) groups (p=1.0). Chest radiographs revealed that catheter tip migration was lesser in the CG group (8.2±6.7 mm) than in the control group (15.0±15.8 mm; p<0.01). There were two cases of venous thrombus formation in the control group.
Conclusion: In a population dominated by esophago-gastroenterological malignancy, peripherally inserted central catheter securement via CG was associated with decreased catheter removal due to suspected catheter infection. Further research on larger cohorts is needed to determine if other adverse events decrease following peripherally inserted central catheter securement via CG.
Reference:
Kurata Y, Ohira G, Hayano K, Imanishi S, Tochigi T, Takahashi Y, Mamiya H, Iwata M, Uesato M, Murakami K, Toyozumi T, Matsumoto Y, Nakano A, Otsuka R, Hayashi H, Matsubara H. Peripherally inserted central catheter securement with cyanoacrylate glue and bloodstream infection: A retrospective cohort study. JPEN J Parenter Enteral Nutr. 2023 Dec 4. doi: 10.1002/jpen.2583. Epub ahead of print. PMID: 38047542.