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"During iron derisomaltose infusion, patient reported iron extravasation. Five months after the incident, the skin stain related to the extravasation was still present" Shi et al (2023).
Intravenous iron extravasation case study

Abstract:

Rationale: Intravenous iron is commonly use in anemia related to chronic kidney disease. Skin staining due to iron extravasation is a rare adverse reaction that can leave a long-term staining of the skin.

Presenting concerns of the patients: During iron derisomaltose infusion, patient reported iron extravasation. Five months after the incident, the skin stain related to the extravasation was still present.

Diagnosis: A case of skin staining due to iron derisomaltose extravasation was diagnosed.

Interventions/outcomes: She was reviewed by dermatology and laser therapy was offered.

Teaching points: Patients and clinicians need to be aware of this complication, and protocol needs to be put in place to minimize extravasation and its complication.

Reference:

Shi R, Marin JG, Beaulieu M. Skin Staining Following Intravenous Iron Extravasation in a Patient With Chronic Kidney Disease: A Case Report. Can J Kidney Health Dis. 2023 Apr 18;10:20543581231165705. doi: 10.1177/20543581231165705. PMID: 37101846; PMCID: PMC10123906.