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"The functionally expanding intravenous catheter failed due to hypersensitivity reactions in patients" Vazquez et al (2021).
Expanding intravenous catheters

Abstract:

Background: Intravenous catheters are common and essential devices within medical practice. Their placement can be difficult, leading to application of several technologies to improve success. Functionally expanding catheters were once an exciting technology, derailed clinically by hypersensitivity reactions. The exact cause of reactions, attributed to Aquavene catheter materials, remains unknown.

Aims: To reinvestigate functionally expanding intravenous catheters.

Materials and methods: The history of the functionally expanding intravenous catheter is presented here along with its utility in current medical practice, potential for further investigation, and possible redesign of these once promising devices.

Results: This review demonstrates clinical utility and a lack of definitive cause for failure of the previous functionally expanding intravenous catheter design. As Aquavene materials themselves are commonly considered the cause of hypersensitivity reactions which removed expanding intravenous catheters from the market, this review found several possible substitutes for this material for use in any redesign.

Discussion and conclusion: The functionally expanding intravenous catheter failed due to hypersensitivity reactions in patients. Alternative materials exist for a possible redesign on this once promising clinical product.

Reference:

Vazquez R, Tennankore R, Shikanov A, Mermel LA, Love B, Burns ML. Re-evaluating expanding intravenous catheters in medical practice. Health Sci Rep. 2021 Jul 1;4(3):e318. doi: 10.1002/hsr2.318. PMID: 34250270; PMCID: PMC8247936.