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"Here we describe a case of asymptomatic port infection detected by manual screening of a peripheral blood smear" Carll et al (2022).

Detecting asymptomatic central line infection

Abstract:

Sickle cell disease is a lifelong disorder which may be managed by chronic red cell transfusion including exchange transfusion. Chronic indwelling vascular catheters including ports offer convenient and reliable access for red cell exchange but confer risk of complications including infection and thrombosis. Detection of these complications is essential for preserving vascular access and relies on both clinical and laboratory observation. Here we describe a case of asymptomatic port infection detected by manual screening of a peripheral blood smear.


Reference:

Carll TC, Mariani R, Schafernak K, Snowberger T, Jacobsen J, Gomez E, Su L. Peripheral Blood Smear Detection of Asymptomatic Central Line Infection in a Patient With Sickle Cell Disease. J Pediatr Hematol Oncol. 2022 Feb 18. doi: 10.1097/MPH.0000000000002432. Epub ahead of print. PMID: 35180760.