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"We suggest this is due to impaired lymphatic flow from the thoracic duct as a result of a central venous catheter in the left subclavian vein" Koop et al (2025).
Neonatal subclavian central venous catheter complication

Abstract:

There are several causes of generalized edema in sick neonates. We describe two newborns that developed progressive and treatment-resistant generalized edema. We suggest this is due to impaired lymphatic flow from the thoracic duct as a result of a central venous catheter in the left subclavian vein.

Reference:

Koop K, de Jel DVC, Nijman J, Peels B, Peters E. Lymphatic Obstruction and Edema in Neonate due to Left Subclavian Central Venous Catheter. Case Rep Pediatr. 2025 Jun 17;2025:2811167. doi: 10.1155/crpe/2811167. PMID: 40556931; PMCID: PMC12187447.

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