Single and double lumen port CLABSI risk
Abstract:
Purpose: To compare the port infection rate between single-lumen and double-lumen ports and to determine if the use of a double-lumen port is an independent risk factor for port infection among cancer patients.
Materials and methods: This retrospective study included 2,573 adult oncologic patients (age >18 years old) who had either a single-lumen (n=841) or a double-lumen (n=1,732) chest port implanted between 2013 and 2020 at a single institution. Patients who had port infection including port-site infection and port-related blood stream infection were identified through chart review. After propensity score matching based on 13 potentially confounding variables, a total of 493 pairs of patients with either single-lumen (SL group) or double-lumen (DL group) ports were subjected to analysis. The port infection rate was compared between groups by using Poisson regression. Multivariate proportional subdistribution hazards regression (PSHREG) analysis was conducted to determine if use of a double lumen port is an independent risk factor for port infection.
Results: The cumulative follow-up period for the matched cohort was 371,853 catheter-days (median: 297 catheter-days per port, range: 0-1903 catheter-days). The port infection rate of the DL group was significantly higher than that of the SL group (0.232 versus 0.113 infections per 1,000 catheter days, p=.001). PSHREG analysis demonstrated that use of a double-lumen port was an independent risk factor of port infection (subdistribution hazard ratio = 2.30, 95% confidence interval = 1.33-3.78, p=.002).
Conclusions: Double-lumen ports were associated with a higher risk of port infection compared to single-lumen ports in adult oncologic patients.
Reference:
She R, Kobayashi K. Comparison of Infection Rates between Single-lumen and Double-lumen Chest Ports Among Cancer Patients: a Propensity Score Matching Analysis. J Vasc Interv Radiol. 2023 Dec 19:S1051-0443(23)00905-3. doi: 10.1016/j.jvir.2023.12.011. Epub ahead of print. PMID: 38128721.