Readmission and mortality following CLABSI
Abstract:
Background: Multidrug-resistant organisms (MDROs) are a common cause of central line-associated bloodstream infections (CLABSIs). The purpose of the study was to determine the relationship between the risk of a patient who had a CLABSI and 90-day mortality and readmission after discharge and the role of age and MDRO status.
Methods: A retrospective analysis including 143 patients from a nine-hospital system examined patients who had a CLABSI between January 2018 to December 2019. Descriptive statistics were performed, with logistic regression analyses performed to identify risk factors.
Results: The results showed there was not a significant difference in mortality (OR = 0.67, p =.550) or readmission (OR = 1.79, p =.215) within 90 days in patients who had an MDRO CLABSI. Age as a covariate showed a 2.7% decreased readmission risk for every 1-year increase in patient age (p =.019). Patients with a non-MDRO CLABSI did not have a significant increased risk in 90-day mortality or readmission (p =.536, p =.211).
Conclusion: Decreased readmission risk from an MDRO associated with increasing age may result from increased patient-provider interactions as patients age. Additional research with a larger study sample is recommended.
Reference:
Crews-Stowe C, Sklar E. Ninety-Day All-Cause Readmission and Mortality Following Central Line-Associated Bloodstream Infection: The Impact of MDRO Status and Age. Am J Infect Control. 2026 Apr 16:S0196-6553(26)00407-4. doi: 10.1016/j.ajic.2026.04.005. Epub ahead of print. PMID: 41997216.