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CHG interventions to reduce CLABSI

clabsi

“This review aimed to identify effective CHG interventions to reduce CLABSIs in patients with cancer, particularly those undergoing bone marrow transplantations” Kuroki et al (2025).

Studying CRBSI with skin-like replicas – Full Text

CLABSI

“In IV therapy simulations, we observed bacterial growth dynamics over the incubation period. Our findings suggest that Ecoflex-based skin-like replicas can serve as a valuable tool for developing and testing new catheters, while the potential for use in other medical innovation devices, including wearable sensing devices, ultimately contributes to improved patient outcomes and infection control strategies” Althumayri et al (2025).

PICU CLABSI risk prediction

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“The risk prediction model for central venous catheter-associated infections in PICU patients is simple, accurate and clinically valuable” Zhang et al (2025).

CLABSI rates in adult intensive care units

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“The aim of this study was to analyze the evolution of device-related infection rates in ICUs over the last 13 years, including ventilator-associated pneumonia (VAP), catheter-related bloodstream infection (CRBSI) and catheter-associated urinary tract infection (CAUTI)” Nuvials et al (2025).

CLABSI rates in pediatric and neonatal intensive care units

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“A standardized surveillance system based on the calculation of the incidence rate of CLABSI in PICUs and NICUs can broaden our understanding of this HAI and will guide the implementation of measures of infection control and prevention” Urrea Ayala et al (2025).

CLABSI reduction in a transplant unit

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“The unit achieved and sustained >90% compliance with both CHG bathing treatments and K-card door tag processes. The CLABSI rate decreased from 2.15 to 0.41, an 81% reduction” Spinks et al (2025).

Adherence to CLABSI prevention bundles

IVTEAM CLABSI

“The purpose of this project was to increase adherence to CLABSI prevention nursing practices and to implement a sustainable program to elevate nurses’ skills and documentation of CLABSI prevention bundle components” Brown et al (2025).

How to reduce central line bloodstream infections in pediatrics

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“In 2022, our pediatric and women’s medical center observed a 166.67% increase in central line bloodstream infections (CLABSIs) in the pediatric population. A quality-focused group was initiated to implement changes to reduce CLABSIs” Kovar et al (2025).

CLABSI rates as a patient safety measure

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“We quantified the impact that stressors associated with the COVID-19 pandemic had on patient safety, as measured by central line-associated bloodstream infections (CLABSIs) reported to the Centers for Disease Control and Prevention’s National Healthcare Safety Network” Sapiano et al (2025).

CLABSI prevention in Finnish intensive care units

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“We conducted a cross-sectional, nationwide survey on awareness of recommended infection prevention practices involving central venous catheters and invasive ventilators in intensive care units” Terho et al (2025).

Hospital-acquired infections in adult intensive care units

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“Due to limited recent literature, we aimed to evaluate the incidence rates and causative organisms of intensive care unit (ICU)-acquired infections at our tertiary care center and to determine the factors associated with mortality in patients with ICU-acquired infections” Zirpe et al (2025).

Neonatal invasive fungal infections

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“Standardized care should include an infection prevention bundle for invasive Candida infections with targeted fluconazole prophylaxis in high-risk patients, antimicrobial stewardship, and central venous catheter-related infection prevention measures” Kaufman and Mukhopadhyay (2025).

App-based CLABSI prevention program – Full Text

CLABSI

“A mobile-app-based CLABSI prevention program decreased the frequency of inflamed/infected central line insertion sites, improved dressing integrity, increased speed of removal when inflammation/infection were found, and reduced infection-related hospitalization risk” Singh et al (2025).

Neonatal sepsis caused by central venous catheter

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“This case report documents the death of a preterm infant due to Bacillus cereus sepsis, septic shock, meningitis, and pneumonia, all of which were linked to the use of a central venous catheter” Xiaoxiao et al (2025).

ICU national BSI surveillance programme – Full Text

CLABSI

“Patients in critical care units (CCUs) are at an increased risk of bloodstream infections (BSIs), which can be associated with central vascular catheters (CVCs). This study describes BSIs, CVC-BSIs, organism distribution, percentage of antimicrobial resistant (AMR) organisms, and case fatality rates (CFRs) over the first six years of a voluntary national CCU surveillance programme in England” Conroy et al (2025).

Whole genome sequencing to characterize CLABSI

CLABSI

“Whole genome sequencing (WGS) and clinical review were used to characterize 14 cases of central line-associated bloodstream infection (CLABSI) due to Staphylococcus epidermidis” Zhou et al (2025).

Chlorhexidine bathing in ICU – Full Text

CLABSI

“This study evaluated the efficacy of daily 2% chlorhexidine gluconate (CHG) bathing in reducing HAI incidence, specifically CAUTI, CLABSI, and multidrug-resistant organisms (MDROs), in a 20-bed ICU at a regional hospital” Chang et al (2025).

Nurse-driven CLABSI prevention in intensive care units

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“As a result, it was observed that the nurse-driven, central catheter-related bloodstream infection prevention algorithm, prepared using evidence-based clinical guidelines, reduced the rates of infection. Therefore, it is recommended to use algorithm studies as a long-term guide in intensive care units” Acun et al (2025).

Adequacy of CLABSI as a quality measure – Full Text

CLABSI

“Efforts should be redirected toward revising the CLABSI definition and possibly reevaluating its criteria. Resources should be assigned to further investigate and systematically prevent BSIs from secondary sources while adhering to existing CLABSI prevention bundles” Mathur et al (2025).

Predicting CLABSI in hemodialysis

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“This study identified six risk factors associated with central venous CRI in MHD patients. This predictive model demonstrates good prognostic performance and can be used by clinicians to screen for high-risk patients with central venous CRI, thereby enabling the early implementation of risk management strategies” Guo et al (2025).

Short-term central venous catheter CLABSI – Full Text

CLABSI

“The aim of this study is to evaluate the incidences of colonization and central line-associated bloodstream infections (CLABSI) in short-term CVCs in the elective surgery setting, as well as to analyze the related risk factors” Becerra-Bolaños et al (2025).

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