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CLABSI reduction using tissue adhesive

IV glue

“To investigate whether tissue adhesive (TA, 2-octyl blended with n-butyl cyanoacrylate) application to centrally/femorally inserted central catheters (CICCs/FICCs) exit sites could reduce the occurrence of central line-associated bloodstream infection (CLABSI)” Kwon et al (2025).

Analysis of CLABSI risk – Full Text

CLABSI

“The goal of this study was to address the misconception that femoral CVCs have a higher associated risk for developing CLABSI compared to other central line sites. This study evaluates risk for CLABSI across FV, IJV, and SCV sites” Vaughan-Masamitsu et al (2025).

Study of CRBSI causative microorganisms – Full Text

CLABSI

“To address CRBSI, one must know the causative microorganisms and their antimicrobial susceptibility profiles. This study aimed to identify the microbes that cause CRBSI and their antimicrobial susceptibility patterns” Poddar et al (2025).

Implementation of structured interventions during ward rounds

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“The main clinical outcomes reported were mortality, infectious complications, length of stay (LOS) and duration of mechanical ventilation (DoMV). Mortality, LOS and rates of urinary tract and central-line associated bloodstream infections did not seem to be affected, positively or negatively, by interventions structuring BWRs” Ando et al (2025).

How to deal with potential CLABSI in haematology patients

clabsi

“Many central lines were removed despite infrequent formal CLABSI diagnoses. Thorough assessments for alternative sources and use of non-invasive diagnostics including repeat blood cultures prior to line removal, may allow increased appropriate retention of lines” Thorburn et al (2025).

Alcohol-impregnated port protectors

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“To investigate the effect of alcohol-impregnated port protectors (AIPPs) on neonatal central line-associated bloodstream infection (CLABSI) rates” Payne et al (2025).

CLABSI prevention among ICU nurses in China

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“In summary, Chinese ICU nurses demonstrated inadequate levels of knowledge and attitude towards CLABSI prevention. Study findings suggest that arranging training in refreshing, taking advantage of experienced nurses’ leading roles and changing safety culture might be useful in enhancing ICU nurses’ knowledge, attitude and practice” He et al (2025).

CLABSI rates in pediatric patients with short bowel syndrome

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“CLABSI rates in pediatric short bowel syndrome have decreased over the past 8 years, yet socioeconomic and racial disparities persist. Efforts to prevent CLABSI across the socioeconomic spectrum should be prioritized to improve short bowel syndrome outcomes” Gutierrez et al (2025).

Neonatal vascular access device infection surveillance – Full Text

CLABSI

“This study aimed to evaluate infection trends, pathogen distribution, and antimicrobial resistance patterns in central and peripheral line-associated bloodstream infections (CLABSIs and PLABSIs) in Victorian Level 6 neonatal intensive care units between July 1st, 2008, and June 30th, 2024” Liu et al (2025).

Prevention of central venous catheter-related infection

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“The findings emphasize the need for targeted educational programs and continuous professional development to address knowledge gaps in CVC-RI prevention. Healthcare institutions should prioritize up-to-date curricula, ongoing training initiatives, and reliable information sources to enhance ICU nurses’ ability to prevent catheter-related infections and improve patient care outcomes” Alshammari et al (2025).

Individualized CLABSI prediction – Full Text

CLABSI

“Central line-associated bloodstream infections (CLABSI) are preventable hospital-acquired infections. Predicting CLABSI helps improve early intervention strategies and enhance patient safety” Albu et al (2025).

Staphylococcus aureus infection in hospitalized infants

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“Historically, Staphylococcus aureus has been a leading cause of morbidity and mortality in the neonatal intensive care unit (NICU). The current incidence and attributable mortality of late-onset invasive S aureus infection in hospitalized infants is unknown” Jennings et al (2025).

CLABSI prevention in oncology patients – Full Text

CLABSI

“To evaluate the impact of a mobile-app-based central line-associated bloodstream infection (CLABSI) prevention program in oncology clinic patients with peripherally inserted central catheters (PICCs)” Saito et al (2025).

Catheter-related bloodstream infection case study – Full Text

CLABSI

“Acinetobacter lwoffii, a low-virulence, non-fermentative gram-negative bacillus, is an uncommon cause of CRBSI. We report the case of a 43-year-old female patient on long-term hemodialysis who developed A. lwoffii-associated CRBSI” Diwan et al (2025).

Surveillance of catheter-related bacteremia

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“We summarize the results of CRB surveillance conducted by the Catalan Program of Surveillance of Nosocomial Infections (VINCat) over the past fifteen years” Gasch et al (2025).

Time to positivity technique for CLABSI diagnosis – Full Text

CLABSI

“The differential time to positivity (DTTP) technique is the recommended conservative procedure to diagnose catheter-related bloodstream infection (C-RBSI). However, its reliability and accuracy remain under debate” Irigoyen-von-Sierakowski et al (2025).

Preventing biofilm formation on central venous catheters – Full Text

CLABSI

“The aim of this study was to evaluate the activity of a cationic arginine-based gemini surfactant, C9(LA)2, against mixed biofilms of fluconazole-resistant Candida albicans and extended-spectrum beta-lactamase (ESBL)-producing E. coli, and the preventive effect of this surfactant impregnated in CVCs on the formation of inter-kingdom biofilms” Pérez et al (2025).

CLABSI in critical care – Full Text

CLABSI

“This study highlights the importance of minimizing CVC use and limiting the number of insertions to reduce CLABSI risk. Effective management strategies should focus on reducing CVC duration and frequency” Alomari et al (2025).

Reducing CLABSI rates in adult ICU

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“Central Line-Associated Bloodstream Infection (CLABSI) remains a leading cause of death among critically ill patients. Implementing preventive measures and adhering to best practices is a crucial action to proactively prevent its occurrence” Mhawish et al (2025).

CRBSI in long-term and acute care wards – Full Text

CLABSI

“This study examined differences in nosocomial-onset urinary tract-related bloodstream infections (UTRBSIs) and catheter-related bloodstream infections (CRBSIs) between patients admitted to long-term and acute care wards” Kumagai et al (2025).

CLABSI risk in ICU patients – Full Text

CLABSI

“The findings underscore the importance of robust surveillance, embedded infection-control and -prevention initiatives, and strict adherence to the CVC care bundle to prevent CLABSI in ICUs” Rajandra et al (2025).

Community CLABSI prevention bundle

IVTEAM CLABSI

“This collaborative project provides the necessary education and resources to manage and streamline central line care in the home and may help prevent complications such as CLABSI” Murray et al (2025).

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